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Literature for peptidase C14.004: caspase-7

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

(Topics flags: S Structure, A Assay, T Target, P Specificity, K Knockout, E Expression, V Review, M Mutation, I Inhibitor, L Localization. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Vidak,E., Vizovisek,M., Kavcic,N., Biasizzo,M., Fonovic,M. and Turk,B.<br>Apoptotic Caspases-3 and -7 Cleave Extracellular Domains of Membrane-Bound Proteins from MDA-MB-231 Breast Cancer Cells<br>Int J Mol Sci (2025) 26 PubMed  Europe PubMed DOI  PMC  EPMC
    2. 2024
  2. Ai,Y., Meng,Y., Yan,B., Zhou,Q. and Wang,X.<br>The biochemical pathways of apoptotic, necroptotic, pyroptotic, and ferroptotic cell death<br>Mol Cell (2024) 84, 170-179. PubMed  Europe PubMed DOI  V
  3. Bertani,F.R., Moghaddam,F.D., Panella,C., Giannitelli,S.M., Peluzzi,V., Gerardino,A., Rainer,A., Roscilli,G., De Ninno,A. and Businaro,L.<br>Kinetic Detection of Apoptosis Events Via Caspase 3/7 Activation in a Tumor-Immune Microenvironment on a Chip<br>Methods Mol Biol (2024) 2748, 109-118. PubMed  Europe PubMed DOI
  4. Ge,J., Wang,Y., Li,X., Lu,Q., Yu,H., Liu,H., Ma,K., Deng,X., Luo,Z.Q., Liu,X. and Qiu,J.<br>Phosphorylation of caspases by a bacterial kinase inhibits host programmed cell death<br>Nat Commun (2024) 15, 8464-8464. PubMed  Europe PubMed DOI  PMC  EPMC
  5. Purnamasari,Y., Hermawati,E., Mujahidin,D., Happyana,N. and Syah,Y.M.<br>Xanthorrhizol derivatives and their biological properties as caspase-7 inhibitors<br>Nat Prod Res (2024) , 1-9. PubMed  Europe PubMed DOI
  6. Xu,H., Yuan,Z., Qin,K., Jiang,S. and Sun,L.<br>The molecular mechanism and evolutionary divergence of caspase 3/7-regulated gasdermin E activation<br>elife (2024) 12 PubMed  Europe PubMed DOI  PMC  EPMC
    7. 2023
  7. Hobbs,K.F., Propp,J., Vance,N.R., Kalenkiewicz,A., Witkin,K.R. and Ashley Spies,M.<br>Allosteric Tuning of Caspase-7: Establishing the Nexus of Structure and Catalytic Power<br>Chemistry (2023) 29, e202300872-e202300872. PubMed  Europe PubMed DOI
  8. Sahoo,G., Samal,D., Khandayataray,P. and Murthy,M.K.<br>A Review on Caspases: Key Regulators of Biological Activities and Apoptosis<br>Mol Neurobiol (2023) 60, 5805-5837. PubMed  Europe PubMed DOI  V
    9. 2022
  9. Ghazavi,F., Huysentruyt,J., De Coninck,J., Kourula,S., Martens,S., Hassannia,B., Wartewig,T., Divert,T., Roelandt,R., Popper,B., Hiergeist,A., Tougaard,P., Vanden Berghe,T., Joossens,M., Berx,G., Takahashi,N., Wahida,A. and Vandenabeele,P.<br>Executioner caspases 3 and 7 are dispensable for intestinal epithelium turnover and homeostasis at steady state<br>Proc Natl Acad Sci U S A (2022) 119 PubMed  Europe PubMed DOI  PMC  EPMC
  10. Nozaki,K., Maltez,V.I., Rayamajhi,M., Tubbs,A.L., Mitchell,J.E., Lacey,C.A., Harvest,C.K., Li,L., Nash,W.T., Larson,H.N., McGlaughon,B.D., Moorman,N.J., Brown,M.G., Whitmire,J.K. and Miao,E.A.<br>Caspase-7 activates ASM to repair gasdermin and perforin pores<br>Nature (2022) 606, 960-967. PubMed  Europe PubMed DOI  PMC  EPMC
  11. Roychowdhury,H. and Romero,P.A.<br>Microfluidic deep mutational scanning of the human executioner caspases reveals differences in structure and regulation<br>Cell Death Discov (2022) 8, 7-7. PubMed  Europe PubMed DOI  PMC  EPMC
    12. 2021
  12. Davies,C.W., Stowe,I., Phung,Q.T., Ho,H., Bakalarski,C.E., Gupta,A., Zhang,Y., Lill,J.R., Payandeh,J., Kayagaki,N. and Koerber,J.T.<br>Discovery of a caspase cleavage motif antibody reveals insights into noncanonical inflammasome function<br>Proc Natl Acad Sci U S A (2021) 118 PubMed  Europe PubMed DOI  PMC  EPMC
  13. Desroches,A. and Denault,J.B.<br>Characterization of caspase-7 interaction with RNA<br>Biochem J (2021) 478, 2681-2696. PubMed  Europe PubMed DOI
  14. Maluch,I., Grzymska,J., Snipas,S.J., Salvesen,G.S. and Drag,M.<br>Evaluation of the effects of phosphorylation of synthetic peptide substrates on their cleavage by caspase-3 and -7<br>Biochem J (2021) 478, 2233-2245. PubMed  Europe PubMed DOI
  15. Ozdemir,A., Ibisoglu,B., Simay Demir,Y.D., Benhur,E., Valipour,F. and Ark,M.<br>A novel proteolytic cleavage of ROCK 1 in cell death: Not only by caspases 3 and 7 but also by caspase 2<br>Biochem Biophys Res Commun (2021) 547, 118-124. PubMed  Europe PubMed DOI
    16. 2020
  16. Chen,X., Chen,D., Huang,L., Chen,X., Zhou,M., Xi,X., Ma,C., Chen,T. and Wang,L.<br>Identification and Target-Modification of SL-BBI: A Novel Bowman-Birk Type Trypsin Inhibitor from Sylvirana latouchii<br>Biomolecules (2020) 10 PubMed  Europe PubMed DOI
  17. de Vasconcelos,N.M., Van Opdenbosch,N., Van Gorp,H., Martin-Perez,R., Zecchin,A., Vandenabeele,P. and Lamkanfi,M.<br>An Apoptotic Caspase Network Safeguards Cell Death Induction in Pyroptotic Macrophages<br>Cell Rep (2020) 32, 107959-107959. PubMed  Europe PubMed DOI
  18. Firoozpour,L., Gao,L., Moghimi,S., Pasalar,P., Davoodi,J., Wang,M.W., Rezaei,Z., Dadgar,A., Yahyavi,H., Amanlou,M. and Foroumadi,A.<br>Efficient synthesis, biological evaluation, and docking study of isatin based derivatives as caspase inhibitors<br>J Enzyme Inhib Med Chem (2020) 35, 1674-1684. PubMed  Europe PubMed DOI  PMC  EPMC  I
  19. Garcia-Arguello,S.F., Lopez-Lorenzo,B., Cornelissen,B. and Smith,G.<br>Development of [(18)F]ICMT-11 for Imaging Caspase-3/7 Activity during Therapy-Induced Apoptosis<br>Cancers (Basel) (2020) 12 PubMed  Europe PubMed DOI  PMC  EPMC  V
  20. Hong,W., Gu,Y., Guan,R., Xie,D., Zhou,H. and Yu,M.<br>Pan-cancer analysis of the CASP gene family in relation to survival, tumor-infiltrating immune cells and therapeutic targets<br>Genomics (2020) PubMed  Europe PubMed DOI
  21. McKenzie,B.A., Fernandes,J.P., Doan,M.A.L., Schmitt,L.M., Branton,W.G. and Power,C.<br>Activation of the executioner caspases-3 and -7 promotes microglial pyroptosis in models of multiple sclerosis<br>J Neuroinflammation (2020) 17, 253-253. PubMed  Europe PubMed DOI  PMC  EPMC  K
  22. Nerlich,A., von Wunsch Teruel,I., Mieth,M., Honzke,K., Ruckert,J.C., Mitchell,T.J., Suttorp,N., Hippenstiel,S. and Hocke,A.C.<br>Reversion of pneumolysin induced executioner caspase activation redirects cells to survival<br>J Infect Dis (2020) PubMed  Europe PubMed DOI
  23. Razai,A.S., Snipas,S.J., Poreba,M., Fasci,D. and Salvesen,G.S.<br>Engineering caspase 7 as an affinity reagent to capture proteolytic products<br>FEBS J (2020) PubMed  Europe PubMed DOI
  24. Safari,F., Farajnia,S., Behzad Behbahani,A., Zarredar,H., Barekati-Mowahed,M. and Dehghani,H.<br>Caspase-7 deficiency in Chinese hamster ovary cells reduces cell proliferation and viability<br>Biol Res (2020) 53, 52-52. PubMed  Europe PubMed DOI  PMC  EPMC
  25. Taki,K., Horie,T., Kida,T., Mimura,M., Ikeda,T. and Oku,H.<br>Impairment of Autophagy Causes Superoxide Formation and Caspase Activation in 661 W Cells, a Cell Line for Cone Photoreceptors, under Hyperglycemic Conditions<br>Int J Mol Sci (2020) 21 PubMed  Europe PubMed DOI  PMC  EPMC
    26. 2019
  26. Bingol,E.N., Sercinoglu,O. and Ozbek,P.<br>How do mutations and allosteric inhibitors modulate caspase-7 activity? A molecular dynamics study<br>J Biomol Struct Dyn (2019) 37, 3456-3466. PubMed  Europe PubMed DOI
  27. Pham,B., Eron,S.J., Hill,M.E., Li,X., Fahie,M.A., Hardy,J.A. and Chen,M.<br>A nanopore approach for analysis of caspase-7 activity in cell lysates<br>Biophys J (2019) 117, 844-855. PubMed  Europe PubMed DOI  A
    28. 2018
  28. Akazawa,K., Sugihara,F., Nakamura,T., Mizukami,S. and Kikuchi,K.<br>Highly sensitive detection of caspase-3/7 activity in living mice using enzyme-responsive (19)F MRI nanoprobes<br>Bioconjug Chem (2018) 29, 1720-1728. PubMed  Europe PubMed DOI  L
  29. Bi,X., Liu,X., Bi,D. and Sun,Y.<br>Identification of caspase-6 and caspase-7 from miiuy croaker and evolution analysis in fish<br>Fish Shellfish Immunol (2018) 83, 406-409. PubMed  Europe PubMed DOI
  30. Pal,A. and Rehemtulla,A.<br>Imaging proteolytic activities in mouse models of cancer<br> (2018) 1731, 247-260. PubMed  Europe PubMed DOI  L
    31. 2017
  31. Martini,C., Bedard,M., Lavigne,P. and Denault,J.B.<br>Characterization of Hsp90 co-chaperone p23 cleavage by caspase-7 uncovers a peptidase-substrate interaction involving intrinsically disordered regions<br>Biochemistry (2017) 56, 5099-5111. PubMed  Europe PubMed DOI
  32. Vance,N.R., Gakhar,L. and Spies,M.A.<br>Allosteric tuning of caspase-7: a fragment-based drug discovery approach<br>Angew Chem Int Ed Engl (2017) 56, 14443-14447. PubMed  Europe PubMed DOI  I
    33. 2016
  33. Baek,H.J., Lee,Y.M., Kim,T.H., Kim,J.Y., Park,E.J., Iwabuchi,K., Mishra,L. and Kim,S.S.<br>Caspase-3/7-mediated cleavage of beta2-spectrin is required for acetaminophen-induced liver damage<br>Int J Biol Sci (2016) 12, 172-183. PubMed  Europe PubMed DOI  PMC  EPMC
  34. Hill,M.E., MacPherson,D.J., Wu,P., Julien,O., Wells,J.A. and Hardy,J.A.<br>Reprogramming caspase-7 specificity by regio-specific mutations and selection provides alternate solutions for substrate recognition<br>ACS Chem Biol (2016) 11, 1603-1612. PubMed  Europe PubMed DOI
  35. Julien,O., Zhuang,M., Wiita,A.P., O'Donoghue,A.J., Knudsen,G.M., Craik,C.S. and Wells,J.A.<br>Quantitative MS-based enzymology of caspases reveals distinct protein substrate specificities, hierarchies, and cellular roles<br>Proc Natl Acad Sci U S A (2016) 113, E2001-E2010. PubMed  Europe PubMed DOI  P
  36. Seaman,J.E., Julien,O., Lee,P.S., Rettenmaier,T.J., Thomsen,N.D. and Wells,J.A.<br>Cacidases: caspases can cleave after aspartate, glutamate and phosphoserine residues<br>Cell Death Differ (2016) 23, 1717-1726. PubMed  Europe PubMed DOI  P
    37. 2015
  37. Guyenet,S.J., Mookerjee,S.S., Lin,A., Custer,S.K., Chen,S.F., Sopher,B.L., La Spada,A.R. and Ellerby,L.M.<br>Proteolytic cleavage of ataxin-7 promotes SCA7 retinal degeneration and neurological dysfunction<br>Hum Mol Genet (2015) 24, 3908-3917. PubMed  Europe PubMed DOI  T
  38. Limpachayaporn,P., Schafers,M. and Haufe,G.<br>Isatin sulfonamides: potent caspases-3 and -7 inhibitors, and promising PET and SPECT radiotracers for apoptosis imaging<br>Future Med Chem (2015) 7, 1173-1196. PubMed  Europe PubMed DOI  L  I
  39. Udemba,A., Smith,G., Nguyen,Q.D., Kaliszczak,M., Carroll,L., Fortt,R., Fuchter,M.J. and Aboagye,E.O.<br>Design, synthesis and initial characterisation of a radiolabelled [(18)F]pyrimidoindolone probe for detecting activated caspase-3/7<br>Org Biomol Chem (2015) 13, 5418-5423. PubMed  Europe PubMed DOI  L
  40. Waldmann,C.M., Hermann,S., Faust,A., Riemann,B., Schober,O., Schafers,M., Haufe,G. and Kopka,K.<br>Novel fluorine-18 labeled 5-(1-pyrrolidinylsulfonyl)-7-azaisatin derivatives as potential PET tracers for in vivo imaging of activated caspases in apoptosis<br>Bioorg Med Chem (2015) 23, 5734-5739. PubMed  Europe PubMed DOI  L
  41. Yuan,Y., Sun,H., Ge,S., Wang,M., Zhao,H., Wang,L., An,L., Zhang,J., Zhang,H., Hu,B., Wang,J. and Liang,G.<br>Controlled intracellular self-assembly and disassembly of 19F nanoparticles for MR imaging of caspase 3/7 in zebrafish<br>ACS Nano (2015) 9, 761-768. PubMed  Europe PubMed DOI  L
    42. 2014
  42. Adamova,E., Liskova,M., Matalova,E. and Kleparnik,K.<br>A miniaturized device for bioluminescence analysis of caspase-3/7 activity in a single apoptotic cell<br>Anal Bioanal Chem (2014) 406, 5389-5394. PubMed  Europe PubMed DOI  L
  43. Flutsch,A., Ackermann,R., Schroeder,T., Lukarska,M., Hausammann,G.J., Weinert,C., Briand,C. and Grutter,M.G.<br>Combined inhibition of caspase 3 and caspase 7 by two highly selective DARPins slows down cellular demise<br>Biochem J (2014) 461, 279-290. PubMed  Europe PubMed DOI
  44. Fuchs,J.E., von Grafenstein,S., Huber,R.G., Wallnoefer,H.G. and Liedl,K.R.<br>Specificity of a protein-protein interface: local dynamics direct substrate recognition of effector caspases<br>Proteins (2014) 82, 546-555. PubMed  Europe PubMed DOI  P
  45. Li,Z., Pan,Y., Zhong,W., Zhu,Y., Zhao,Y., Li,L., Liu,W., Zhou,H. and Yang,C.<br>Synthesis and evaluation of N-acyl-substituted 1,2-benzisothiazol-3-one derivatives as caspase-3 inhibitors<br>Bioorg Med Chem (2014) 22, 6735-6745. PubMed  Europe PubMed DOI  I
  46. Ye,D., Shuhendler,A.J., Pandit,P., Brewer,K.D., Tee,S.S., Cui,L., Tikhomirov,G., Rutt,B. and Rao,J.<br>Caspase-responsive smart gadolinium-based contrast agent for magnetic resonance imaging of drug-induced apoptosis<br>Chem Sci (2014) 4, 3845-3852. PubMed  Europe PubMed DOI  PMC  EPMC  L
    47. 2013
  47. Brentnall,M., Rodriguez-Menocal,L., De Guevara,R.L., Cepero,E. and Boise,L.H.<br>Caspase-9, caspase-3 and caspase-7 have distinct roles during intrinsic apoptosis<br>BMC Cell Biol (2013) 14, 32-32. PubMed  Europe PubMed DOI  PMC  EPMC
  48. Choudhury,S., Bhootada,Y., Gorbatyuk,O. and Gorbatyuk,M.<br>Caspase-7 ablation modulates UPR, reprograms TRAF2-JNK apoptosis and protects T17M rhodopsin mice from severe retinal degeneration<br>Cell Death Dis (2013) 4, e528-e528. PubMed  Europe PubMed DOI  K
  49. Galban,S., Jeon,Y.H., Bowman,B.M., Stevenson,J., Sebolt,K.A., Sharkey,L.M., Lafferty,M., Hoff,B.A., Butler,B.L., Wigdal,S.S., Binkowski,B.F., Otto,P., Zimmerman,K., Vidugiris,G., Encell,L.P., Fan,F., Wood,K.V., Galban,C.J., Ross,B.D. and Rehemtulla,A.<br>Imaging proteolytic activity in live cells and animal models<br>PLoS ONE (2013) 8, e66248-e66248. PubMed  Europe PubMed DOI  PMC  EPMC  L
  50. Guicciardi,M.E. and Gores,G.J.<br>Unshackling caspase-7 for cancer therapy<br>J Clin Invest (2013) 123, 3706-3708. PubMed  Europe PubMed DOI  PMC  EPMC
  51. Kang,H.J., Lee,Y.M., Bae,K.H., Kim,S.J. and Chung,S.J.<br>Structural asymmetry of procaspase-7 bound to a specific inhibitor<br>Acta Crystallogr Sect D Biol Crystallogr (2013) 69, 1514-1521. PubMed  Europe PubMed DOI  S  I
  52. Krause-Heuer,A.M., Howell,N.R., Matesic,L., Dhand,G., Young,E.L., Burgess,L., Jiang,C.D., Lengkeek,N.A., Fookes,C.J.R., Pham,T.Q., Sobrio,F., Greguric,I. and Fraser,B.H.<br>A new class of fluorinated 5-pyrrolidinylsulfonyl isatin caspase inhibitors for PET imaging of apoptosis<br>MedChemComm (2013) 4, 347-352. DOI  L  I
  53. Limpachayaporn,P., Schafers,M., Schober,O., Kopka,K. and Haufe,G.<br>Synthesis of new fluorinated, 2-substituted 5-pyrrolidinylsulfonyl isatin derivatives as caspase-3 and caspase-7 inhibitors: Nonradioactive counterparts of putative PET-compatible apoptosis imaging agents<br>Bioorg Med Chem (2013) 21, 2025-2036. PubMed  Europe PubMed DOI  I
  54. Limpachayaporn,P., Riemann,B., Kopka,K., Schober,O., Schafers,M. and Haufe,G.<br>Influence of 4- or 5-substituents on the pyrrolidine ring of 5-[1-(2-methoxymethylpyrrolidinyl)sulfonyl]isatin derivatives on their inhibitory activities towards caspases-3 and -7<br>Eur J Med Chem (2013) 64, 562-578. PubMed  Europe PubMed DOI  I
  55. Lin,Y.F., Lai,T.C., Chang,C.K., Chen,C.L., Huang,M.S., Yang,C.J., Liu,H.G., Dong,J.J., Chou,Y.A., Teng,K.H., Chen,S.H., Tian,W.T., Jan,Y.H., Hsiao,M. and Liang,P.H.<br>Targeting the XIAP/caspase-7 complex selectively kills caspase-3-deficient malignancies<br>J Clin Invest (2013) 123, 3861-3875. PubMed  Europe PubMed DOI  PMC  EPMC
  56. Thomsen,N.D., Koerber,J.T. and Wells,J.A.<br>Structural snapshots reveal distinct mechanisms of procaspase-3 and -7 activation<br>Proc Natl Acad Sci U S A (2013) 110, 8477-8482. PubMed  Europe PubMed DOI  S
    57. 2012
  57. Cassidy,S.K., Hagar,J.A., Kanneganti,T.D., Franchi,L., Nunez,G. and O'Riordan,M.X.<br>Membrane Damage during Listeria monocytogenes Infection Triggers a Caspase-7 Dependent Cytoprotective Response<br>PLoS Pathog (2012) 8, e1002628-e1002628. PubMed  Europe PubMed DOI  PMC  EPMC
  58. Feldman,T., Kabaleeswaran,V., Jang,S.B., Antczak,C., Djaballah,H., Wu,H. and Jiang,X.<br>A class of allosteric caspase inhibitors identified by high-throughput screening<br>Mol Cell (2012) 47, 585-595. PubMed  Europe PubMed DOI  I
  59. Kang,H.J., Lee,Y.M., Jeong,M.S., Kim,M., Bae,K.H., Kim,S.J. and Chung,S.J.<br>Molecular insight into the role of the leucine residue on the L2 loop in the catalytic activity of caspases 3 and 7<br>Biosci Rep (2012) 32, 305-313. PubMed  Europe PubMed DOI
  60. Nguyen,Q.D., Challapalli,A., Smith,G., Fortt,R. and Aboagye,E.O.<br>Imaging apoptosis with positron emission tomography: 'Bench to bedside' development of the caspase-3/7 specific radiotracer [(18)F]ICMT-11<br>Eur J Cancer (2012) 48, 432-440. PubMed  Europe PubMed DOI  L
  61. Roschitzki-Voser,H., Schroeder,T., Lenherr,E.D., Frolich,F., Schweizer,A., Donepudi,M., Ganesan,R., Mittl,P.R., Baici,A. and Grutter,M.G.<br>Human caspases in vitro: expression, purification and kinetic characterization<br>Protein Expr Purif (2012) 84, 236-246. PubMed  Europe PubMed DOI  E
  62. Vanden Berghe,T., Kersse,K. and Vandenabeele,P.<br>Caspase-3 and caspase-7<br>[ISSN:978-0-12-407743-0] (2012) 3, 2256-2265. DOI
    63. 2011
  63. Boucher,D., Blais,V., Drag,M. and Denault,J.B.<br>Molecular determinants involved in activation of caspase 7<br>Biosci Rep (2011) 31, 283-294. PubMed  Europe PubMed DOI
  64. Burguillos,M.A., Deierborg,T., Kavanagh,E., Persson,A., Hajji,N., Garcia-Quintanilla,A., Cano,J., Brundin,P., Englund,E., Venero,J.L. and Joseph,B.<br>Caspase signalling controls microglia activation and neurotoxicity<br>Nature (2011) 472, 319-324. PubMed  Europe PubMed DOI
  65. Edelmann,B., Bertsch,U., Tchikov,V., Winoto-Morbach,S., Perrotta,C., Jakob,M., Adam-Klages,S., Kabelitz,D. and Schutze,S.<br>Caspase-8 and caspase-7 sequentially mediate proteolytic activation of acid sphingomyelinase in TNF-R1 receptosomes<br>EMBO J (2011) 30, 379-394. PubMed  Europe PubMed DOI  P
  66. Scabini,M., Stellari,F., Cappella,P., Rizzitano,S., Texido,G. and Pesenti,E.<br>In vivo imaging of early stage apoptosis by measuring real-time caspase-3/7 activation<br>Apoptosis (2011) 16, 198-207. PubMed  Europe PubMed DOI  L
  67. Soares,J., Lowe,M.M. and Jarstfer,M.B.<br>The catalytic subunit of human telomerase is a unique caspase-6 and caspase-7 substrate<br>Biochemistry (2011) 50, 9046-9055. PubMed  Europe PubMed DOI  P
  68. Witkowski,W.A. and Hardy,J.A.<br>A designed redox-controlled caspase<br>Protein Sci (2011) 20, 1421-1431. PubMed  Europe PubMed DOI
    69. 2010
  69. Gray,D.C., Mahrus,S. and Wells,J.A.<br>Activation of specific apoptotic caspases with an engineered small-molecule-activated protease<br>Cell (2010) 142, 637-646. PubMed  Europe PubMed DOI
  70. Lamkanfi,M. and Kanneganti,T.D.<br>Caspase-7: a protease involved in apoptosis and inflammation<br>Int J Biochem Cell Biol (2010) 42, 21-24. PubMed  Europe PubMed DOI  T
  71. Lee,Y.M., Kang,H.J., Jang,M., Kim,M., Bae,K.H. and Chung,S.J.<br>Large-scale expression in Escherichia coli and efficient purification of precursor and active caspase-7 by introduction of thrombin cleavage sites<br>Protein Expr Purif (2010) 69, 29-33. PubMed  Europe PubMed DOI  E
  72. Miscione,G.P., Calvaresi,M. and Bottoni,A.<br>Computational evidence for the catalytic mechanism of caspase-7. A DFT investigation<br>J Phys Chem B (2010) 114, 4637-4645. PubMed  Europe PubMed DOI
    73. 2009
  73. Agniswamy,J., Fang,B. and Weber,I.T.<br>Conformational similarity in the activation of caspase-3 and -7 revealed by the unliganded and inhibited structures of caspase-7<br>Apoptosis (2009) 14, 1135-1144. PubMed  Europe PubMed DOI  S
  74. Akhter,A., Gavrilin,M.A., Frantz,L., Washington,S., Ditty,C., Limoli,D., Day,C., Sarkar,A., Newland,C., Butchar,J., Marsh,C.B., Wewers,M.D., Tridandapani,S., Kanneganti,T.D. and Amer,A.O.<br>Caspase-7 activation by the Nlrc4/Ipaf inflammasome restricts Legionella pneumophila infection<br>PLoS Pathog (2009) 5, e1000361-e1000361. PubMed  Europe PubMed DOI  PMC  EPMC
  75. Alves,J., Wurdak,H., Garay-Malpartida,H.M., Harris,J.L., Occhiucci,J.M., Belizario,J.E. and Li,J.<br>TAF15 and the leukemia-associated fusion protein TAF15-CIZ/NMP4 are cleaved by caspases-3 and -7<br>Biochem Biophys Res Commun (2009) 384, 495-500. PubMed  Europe PubMed DOI  P
  76. Demon,D., Van Damme,P., Vanden Berghe,T., Deceuninck,A., Van Durme,J., Verspurten,J., Helsens,K., Impens,F., Wejda,M., Schymkowitz,J., Rousseau,F., Madder,A., Vandekerckhove,J., Declercq,W., Gevaert,K. and Vandenabeele,P.<br>Proteome-wide substrate analysis indicates substrate exclusion as a mechanism to generate caspase-7 versus caspase-3 specificity<br>Mol Cell Proteomics (2009) 8, 2700-2714. PubMed  Europe PubMed DOI  P
  77. Gafni,J., Cong,X., Chen,S.F., Gibson,B.W. and Ellerby,L.M.<br>Calpain-1 cleaves and activates caspase-7<br>J Biol Chem (2009) 284, 25441-25449. PubMed  Europe PubMed DOI  PMC  EPMC
  78. Hardy,J.A. and Wells,J.A.<br>Dissecting an allosteric switch in caspase-7 using chemical and mutational probes<br>J Biol Chem (2009) 284, 26063-26069. PubMed  Europe PubMed DOI  PMC  EPMC
  79. Lee,W.K., Kim,J.S., Kang,H.G., Cha,S.I., Kim,D.S., Hyun,D.S., Kam,S., Kim,C.H., Jung,T.H. and Park,J.Y.<br>Polymorphisms in the caspase7 gene and the risk of lung cancer<br>Lung Cancer (2009) 65, 19-24. PubMed  Europe PubMed DOI  M
  80. Podichetty,A.K., Faust,A., Kopka,K., Wagner,S., Schober,O., Schafers,M. and Haufe,G.<br>Fluorinated isatin derivatives. Part 1: Synthesis of new N-substituted (S)-5-[1-(2-methoxymethylpyrrolidinyl)sulfonyl]isatins as potent caspase-3 and -7 inhibitors<br>Bioorg Med Chem (2009) 17, 2680-2688. PubMed  Europe PubMed DOI  I
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