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Literature for peptidase C14.004: caspase-7

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Inhibitors Pharma

(Topics flags: S Structure, A Assay, T Target, P Specificity, K Knockout, E Expression, V Review, M Mutation, I Inhibitor, L Localization. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Vidak,E., Vizovisek,M., Kavcic,N., Biasizzo,M., Fonovic,M. and Turk,B.
    Apoptotic Caspases-3 and -7 Cleave Extracellular Domains of Membrane-Bound Proteins from MDA-MB-231 Breast Cancer Cells
    Int J Mol Sci (2025) 26 PubMed  Europe PubMed DOI  PMC  EPMC
    2. 2024
  2. Ai,Y., Meng,Y., Yan,B., Zhou,Q. and Wang,X.
    The biochemical pathways of apoptotic, necroptotic, pyroptotic, and ferroptotic cell death
    Mol Cell (2024) 84, 170-179. PubMed  Europe PubMed DOI  V
  3. Bertani,F.R., Moghaddam,F.D., Panella,C., Giannitelli,S.M., Peluzzi,V., Gerardino,A., Rainer,A., Roscilli,G., De Ninno,A. and Businaro,L.
    Kinetic Detection of Apoptosis Events Via Caspase 3/7 Activation in a Tumor-Immune Microenvironment on a Chip
    Methods Mol Biol (2024) 2748, 109-118. PubMed  Europe PubMed DOI
  4. Ge,J., Wang,Y., Li,X., Lu,Q., Yu,H., Liu,H., Ma,K., Deng,X., Luo,Z.Q., Liu,X. and Qiu,J.
    Phosphorylation of caspases by a bacterial kinase inhibits host programmed cell death
    Nat Commun (2024) 15, 8464-8464. PubMed  Europe PubMed DOI  PMC  EPMC
  5. Purnamasari,Y., Hermawati,E., Mujahidin,D., Happyana,N. and Syah,Y.M.
    Xanthorrhizol derivatives and their biological properties as caspase-7 inhibitors
    Nat Prod Res (2024) , 1-9. PubMed  Europe PubMed DOI
  6. Xu,H., Yuan,Z., Qin,K., Jiang,S. and Sun,L.
    The molecular mechanism and evolutionary divergence of caspase 3/7-regulated gasdermin E activation
    elife (2024) 12 PubMed  Europe PubMed DOI  PMC  EPMC
    7. 2023
  7. Hobbs,K.F., Propp,J., Vance,N.R., Kalenkiewicz,A., Witkin,K.R. and Ashley Spies,M.
    Allosteric Tuning of Caspase-7: Establishing the Nexus of Structure and Catalytic Power
    Chemistry (2023) 29, e202300872-e202300872. PubMed  Europe PubMed DOI
  8. Sahoo,G., Samal,D., Khandayataray,P. and Murthy,M.K.
    A Review on Caspases: Key Regulators of Biological Activities and Apoptosis
    Mol Neurobiol (2023) 60, 5805-5837. PubMed  Europe PubMed DOI  V
    9. 2022
  9. Ghazavi,F., Huysentruyt,J., De Coninck,J., Kourula,S., Martens,S., Hassannia,B., Wartewig,T., Divert,T., Roelandt,R., Popper,B., Hiergeist,A., Tougaard,P., Vanden Berghe,T., Joossens,M., Berx,G., Takahashi,N., Wahida,A. and Vandenabeele,P.
    Executioner caspases 3 and 7 are dispensable for intestinal epithelium turnover and homeostasis at steady state
    Proc Natl Acad Sci U S A (2022) 119 PubMed  Europe PubMed DOI  PMC  EPMC
  10. Nozaki,K., Maltez,V.I., Rayamajhi,M., Tubbs,A.L., Mitchell,J.E., Lacey,C.A., Harvest,C.K., Li,L., Nash,W.T., Larson,H.N., McGlaughon,B.D., Moorman,N.J., Brown,M.G., Whitmire,J.K. and Miao,E.A.
    Caspase-7 activates ASM to repair gasdermin and perforin pores
    Nature (2022) 606, 960-967. PubMed  Europe PubMed DOI  PMC  EPMC
  11. Roychowdhury,H. and Romero,P.A.
    Microfluidic deep mutational scanning of the human executioner caspases reveals differences in structure and regulation
    Cell Death Discov (2022) 8, 7-7. PubMed  Europe PubMed DOI  PMC  EPMC
    12. 2021
  12. Davies,C.W., Stowe,I., Phung,Q.T., Ho,H., Bakalarski,C.E., Gupta,A., Zhang,Y., Lill,J.R., Payandeh,J., Kayagaki,N. and Koerber,J.T.
    Discovery of a caspase cleavage motif antibody reveals insights into noncanonical inflammasome function
    Proc Natl Acad Sci U S A (2021) 118 PubMed  Europe PubMed DOI  PMC  EPMC
  13. Desroches,A. and Denault,J.B.
    Characterization of caspase-7 interaction with RNA
    Biochem J (2021) 478, 2681-2696. PubMed  Europe PubMed DOI
  14. Maluch,I., Grzymska,J., Snipas,S.J., Salvesen,G.S. and Drag,M.
    Evaluation of the effects of phosphorylation of synthetic peptide substrates on their cleavage by caspase-3 and -7
    Biochem J (2021) 478, 2233-2245. PubMed  Europe PubMed DOI
  15. Ozdemir,A., Ibisoglu,B., Simay Demir,Y.D., Benhur,E., Valipour,F. and Ark,M.
    A novel proteolytic cleavage of ROCK 1 in cell death: Not only by caspases 3 and 7 but also by caspase 2
    Biochem Biophys Res Commun (2021) 547, 118-124. PubMed  Europe PubMed DOI
    16. 2020
  16. Chen,X., Chen,D., Huang,L., Chen,X., Zhou,M., Xi,X., Ma,C., Chen,T. and Wang,L.
    Identification and Target-Modification of SL-BBI: A Novel Bowman-Birk Type Trypsin Inhibitor from Sylvirana latouchii
    Biomolecules (2020) 10 PubMed  Europe PubMed DOI
  17. de Vasconcelos,N.M., Van Opdenbosch,N., Van Gorp,H., Martin-Perez,R., Zecchin,A., Vandenabeele,P. and Lamkanfi,M.
    An Apoptotic Caspase Network Safeguards Cell Death Induction in Pyroptotic Macrophages
    Cell Rep (2020) 32, 107959-107959. PubMed  Europe PubMed DOI
  18. Firoozpour,L., Gao,L., Moghimi,S., Pasalar,P., Davoodi,J., Wang,M.W., Rezaei,Z., Dadgar,A., Yahyavi,H., Amanlou,M. and Foroumadi,A.
    Efficient synthesis, biological evaluation, and docking study of isatin based derivatives as caspase inhibitors
    J Enzyme Inhib Med Chem (2020) 35, 1674-1684. PubMed  Europe PubMed DOI  PMC  EPMC  I
  19. Garcia-Arguello,S.F., Lopez-Lorenzo,B., Cornelissen,B. and Smith,G.
    Development of [(18)F]ICMT-11 for Imaging Caspase-3/7 Activity during Therapy-Induced Apoptosis
    Cancers (Basel) (2020) 12 PubMed  Europe PubMed DOI  PMC  EPMC  V
  20. Hong,W., Gu,Y., Guan,R., Xie,D., Zhou,H. and Yu,M.
    Pan-cancer analysis of the CASP gene family in relation to survival, tumor-infiltrating immune cells and therapeutic targets
    Genomics (2020) PubMed  Europe PubMed DOI
  21. McKenzie,B.A., Fernandes,J.P., Doan,M.A.L., Schmitt,L.M., Branton,W.G. and Power,C.
    Activation of the executioner caspases-3 and -7 promotes microglial pyroptosis in models of multiple sclerosis
    J Neuroinflammation (2020) 17, 253-253. PubMed  Europe PubMed DOI  PMC  EPMC  K
  22. Nerlich,A., von Wunsch Teruel,I., Mieth,M., Honzke,K., Ruckert,J.C., Mitchell,T.J., Suttorp,N., Hippenstiel,S. and Hocke,A.C.
    Reversion of pneumolysin induced executioner caspase activation redirects cells to survival
    J Infect Dis (2020) PubMed  Europe PubMed DOI
  23. Razai,A.S., Snipas,S.J., Poreba,M., Fasci,D. and Salvesen,G.S.
    Engineering caspase 7 as an affinity reagent to capture proteolytic products
    FEBS J (2020) PubMed  Europe PubMed DOI
  24. Safari,F., Farajnia,S., Behzad Behbahani,A., Zarredar,H., Barekati-Mowahed,M. and Dehghani,H.
    Caspase-7 deficiency in Chinese hamster ovary cells reduces cell proliferation and viability
    Biol Res (2020) 53, 52-52. PubMed  Europe PubMed DOI  PMC  EPMC
  25. Taki,K., Horie,T., Kida,T., Mimura,M., Ikeda,T. and Oku,H.
    Impairment of Autophagy Causes Superoxide Formation and Caspase Activation in 661 W Cells, a Cell Line for Cone Photoreceptors, under Hyperglycemic Conditions
    Int J Mol Sci (2020) 21 PubMed  Europe PubMed DOI  PMC  EPMC
    26. 2019
  26. Bingol,E.N., Sercinoglu,O. and Ozbek,P.
    How do mutations and allosteric inhibitors modulate caspase-7 activity? A molecular dynamics study
    J Biomol Struct Dyn (2019) 37, 3456-3466. PubMed  Europe PubMed DOI
  27. Pham,B., Eron,S.J., Hill,M.E., Li,X., Fahie,M.A., Hardy,J.A. and Chen,M.
    A nanopore approach for analysis of caspase-7 activity in cell lysates
    Biophys J (2019) 117, 844-855. PubMed  Europe PubMed DOI  A
    28. 2018
  28. Akazawa,K., Sugihara,F., Nakamura,T., Mizukami,S. and Kikuchi,K.
    Highly sensitive detection of caspase-3/7 activity in living mice using enzyme-responsive (19)F MRI nanoprobes
    Bioconjug Chem (2018) 29, 1720-1728. PubMed  Europe PubMed DOI  L
  29. Bi,X., Liu,X., Bi,D. and Sun,Y.
    Identification of caspase-6 and caspase-7 from miiuy croaker and evolution analysis in fish
    Fish Shellfish Immunol (2018) 83, 406-409. PubMed  Europe PubMed DOI
  30. Pal,A. and Rehemtulla,A.
    Imaging proteolytic activities in mouse models of cancer
     (2018) 1731, 247-260. PubMed  Europe PubMed DOI  L
    31. 2017
  31. Martini,C., Bedard,M., Lavigne,P. and Denault,J.B.
    Characterization of Hsp90 co-chaperone p23 cleavage by caspase-7 uncovers a peptidase-substrate interaction involving intrinsically disordered regions
    Biochemistry (2017) 56, 5099-5111. PubMed  Europe PubMed DOI
  32. Vance,N.R., Gakhar,L. and Spies,M.A.
    Allosteric tuning of caspase-7: a fragment-based drug discovery approach
    Angew Chem Int Ed Engl (2017) 56, 14443-14447. PubMed  Europe PubMed DOI  I
    33. 2016
  33. Baek,H.J., Lee,Y.M., Kim,T.H., Kim,J.Y., Park,E.J., Iwabuchi,K., Mishra,L. and Kim,S.S.
    Caspase-3/7-mediated cleavage of beta2-spectrin is required for acetaminophen-induced liver damage
    Int J Biol Sci (2016) 12, 172-183. PubMed  Europe PubMed DOI  PMC  EPMC
  34. Hill,M.E., MacPherson,D.J., Wu,P., Julien,O., Wells,J.A. and Hardy,J.A.
    Reprogramming caspase-7 specificity by regio-specific mutations and selection provides alternate solutions for substrate recognition
    ACS Chem Biol (2016) 11, 1603-1612. PubMed  Europe PubMed DOI
  35. Julien,O., Zhuang,M., Wiita,A.P., O'Donoghue,A.J., Knudsen,G.M., Craik,C.S. and Wells,J.A.
    Quantitative MS-based enzymology of caspases reveals distinct protein substrate specificities, hierarchies, and cellular roles
    Proc Natl Acad Sci U S A (2016) 113, E2001-E2010. PubMed  Europe PubMed DOI  P
  36. Seaman,J.E., Julien,O., Lee,P.S., Rettenmaier,T.J., Thomsen,N.D. and Wells,J.A.
    Cacidases: caspases can cleave after aspartate, glutamate and phosphoserine residues
    Cell Death Differ (2016) 23, 1717-1726. PubMed  Europe PubMed DOI  P
    37. 2015
  37. Guyenet,S.J., Mookerjee,S.S., Lin,A., Custer,S.K., Chen,S.F., Sopher,B.L., La Spada,A.R. and Ellerby,L.M.
    Proteolytic cleavage of ataxin-7 promotes SCA7 retinal degeneration and neurological dysfunction
    Hum Mol Genet (2015) 24, 3908-3917. PubMed  Europe PubMed DOI  T
  38. Limpachayaporn,P., Schafers,M. and Haufe,G.
    Isatin sulfonamides: potent caspases-3 and -7 inhibitors, and promising PET and SPECT radiotracers for apoptosis imaging
    Future Med Chem (2015) 7, 1173-1196. PubMed  Europe PubMed DOI  L  I
  39. Udemba,A., Smith,G., Nguyen,Q.D., Kaliszczak,M., Carroll,L., Fortt,R., Fuchter,M.J. and Aboagye,E.O.
    Design, synthesis and initial characterisation of a radiolabelled [(18)F]pyrimidoindolone probe for detecting activated caspase-3/7
    Org Biomol Chem (2015) 13, 5418-5423. PubMed  Europe PubMed DOI  L
  40. Waldmann,C.M., Hermann,S., Faust,A., Riemann,B., Schober,O., Schafers,M., Haufe,G. and Kopka,K.
    Novel fluorine-18 labeled 5-(1-pyrrolidinylsulfonyl)-7-azaisatin derivatives as potential PET tracers for in vivo imaging of activated caspases in apoptosis
    Bioorg Med Chem (2015) 23, 5734-5739. PubMed  Europe PubMed DOI  L
  41. Yuan,Y., Sun,H., Ge,S., Wang,M., Zhao,H., Wang,L., An,L., Zhang,J., Zhang,H., Hu,B., Wang,J. and Liang,G.
    Controlled intracellular self-assembly and disassembly of 19F nanoparticles for MR imaging of caspase 3/7 in zebrafish
    ACS Nano (2015) 9, 761-768. PubMed  Europe PubMed DOI  L
    42. 2014
  42. Adamova,E., Liskova,M., Matalova,E. and Kleparnik,K.
    A miniaturized device for bioluminescence analysis of caspase-3/7 activity in a single apoptotic cell
    Anal Bioanal Chem (2014) 406, 5389-5394. PubMed  Europe PubMed DOI  L
  43. Flutsch,A., Ackermann,R., Schroeder,T., Lukarska,M., Hausammann,G.J., Weinert,C., Briand,C. and Grutter,M.G.
    Combined inhibition of caspase 3 and caspase 7 by two highly selective DARPins slows down cellular demise
    Biochem J (2014) 461, 279-290. PubMed  Europe PubMed DOI
  44. Fuchs,J.E., von Grafenstein,S., Huber,R.G., Wallnoefer,H.G. and Liedl,K.R.
    Specificity of a protein-protein interface: local dynamics direct substrate recognition of effector caspases
    Proteins (2014) 82, 546-555. PubMed  Europe PubMed DOI  P
  45. Li,Z., Pan,Y., Zhong,W., Zhu,Y., Zhao,Y., Li,L., Liu,W., Zhou,H. and Yang,C.
    Synthesis and evaluation of N-acyl-substituted 1,2-benzisothiazol-3-one derivatives as caspase-3 inhibitors
    Bioorg Med Chem (2014) 22, 6735-6745. PubMed  Europe PubMed DOI  I
  46. Ye,D., Shuhendler,A.J., Pandit,P., Brewer,K.D., Tee,S.S., Cui,L., Tikhomirov,G., Rutt,B. and Rao,J.
    Caspase-responsive smart gadolinium-based contrast agent for magnetic resonance imaging of drug-induced apoptosis
    Chem Sci (2014) 4, 3845-3852. PubMed  Europe PubMed DOI  PMC  EPMC  L
    47. 2013
  47. Brentnall,M., Rodriguez-Menocal,L., De Guevara,R.L., Cepero,E. and Boise,L.H.
    Caspase-9, caspase-3 and caspase-7 have distinct roles during intrinsic apoptosis
    BMC Cell Biol (2013) 14, 32-32. PubMed  Europe PubMed DOI  PMC  EPMC
  48. Choudhury,S., Bhootada,Y., Gorbatyuk,O. and Gorbatyuk,M.
    Caspase-7 ablation modulates UPR, reprograms TRAF2-JNK apoptosis and protects T17M rhodopsin mice from severe retinal degeneration
    Cell Death Dis (2013) 4, e528-e528. PubMed  Europe PubMed DOI  K
  49. Galban,S., Jeon,Y.H., Bowman,B.M., Stevenson,J., Sebolt,K.A., Sharkey,L.M., Lafferty,M., Hoff,B.A., Butler,B.L., Wigdal,S.S., Binkowski,B.F., Otto,P., Zimmerman,K., Vidugiris,G., Encell,L.P., Fan,F., Wood,K.V., Galban,C.J., Ross,B.D. and Rehemtulla,A.
    Imaging proteolytic activity in live cells and animal models
    PLoS ONE (2013) 8, e66248-e66248. PubMed  Europe PubMed DOI  PMC  EPMC  L
  50. Guicciardi,M.E. and Gores,G.J.
    Unshackling caspase-7 for cancer therapy
    J Clin Invest (2013) 123, 3706-3708. PubMed  Europe PubMed DOI  PMC  EPMC
  51. Kang,H.J., Lee,Y.M., Bae,K.H., Kim,S.J. and Chung,S.J.
    Structural asymmetry of procaspase-7 bound to a specific inhibitor
    Acta Crystallogr Sect D Biol Crystallogr (2013) 69, 1514-1521. PubMed  Europe PubMed DOI  S  I
  52. Krause-Heuer,A.M., Howell,N.R., Matesic,L., Dhand,G., Young,E.L., Burgess,L., Jiang,C.D., Lengkeek,N.A., Fookes,C.J.R., Pham,T.Q., Sobrio,F., Greguric,I. and Fraser,B.H.
    A new class of fluorinated 5-pyrrolidinylsulfonyl isatin caspase inhibitors for PET imaging of apoptosis
    MedChemComm (2013) 4, 347-352. DOI  L  I
  53. Limpachayaporn,P., Schafers,M., Schober,O., Kopka,K. and Haufe,G.
    Synthesis of new fluorinated, 2-substituted 5-pyrrolidinylsulfonyl isatin derivatives as caspase-3 and caspase-7 inhibitors: Nonradioactive counterparts of putative PET-compatible apoptosis imaging agents
    Bioorg Med Chem (2013) 21, 2025-2036. PubMed  Europe PubMed DOI  I
  54. Limpachayaporn,P., Riemann,B., Kopka,K., Schober,O., Schafers,M. and Haufe,G.
    Influence of 4- or 5-substituents on the pyrrolidine ring of 5-[1-(2-methoxymethylpyrrolidinyl)sulfonyl]isatin derivatives on their inhibitory activities towards caspases-3 and -7
    Eur J Med Chem (2013) 64, 562-578. PubMed  Europe PubMed DOI  I
  55. Lin,Y.F., Lai,T.C., Chang,C.K., Chen,C.L., Huang,M.S., Yang,C.J., Liu,H.G., Dong,J.J., Chou,Y.A., Teng,K.H., Chen,S.H., Tian,W.T., Jan,Y.H., Hsiao,M. and Liang,P.H.
    Targeting the XIAP/caspase-7 complex selectively kills caspase-3-deficient malignancies
    J Clin Invest (2013) 123, 3861-3875. PubMed  Europe PubMed DOI  PMC  EPMC
  56. Thomsen,N.D., Koerber,J.T. and Wells,J.A.
    Structural snapshots reveal distinct mechanisms of procaspase-3 and -7 activation
    Proc Natl Acad Sci U S A (2013) 110, 8477-8482. PubMed  Europe PubMed DOI  S
    57. 2012
  57. Cassidy,S.K., Hagar,J.A., Kanneganti,T.D., Franchi,L., Nunez,G. and O'Riordan,M.X.
    Membrane Damage during Listeria monocytogenes Infection Triggers a Caspase-7 Dependent Cytoprotective Response
    PLoS Pathog (2012) 8, e1002628-e1002628. PubMed  Europe PubMed DOI  PMC  EPMC
  58. Feldman,T., Kabaleeswaran,V., Jang,S.B., Antczak,C., Djaballah,H., Wu,H. and Jiang,X.
    A class of allosteric caspase inhibitors identified by high-throughput screening
    Mol Cell (2012) 47, 585-595. PubMed  Europe PubMed DOI  I
  59. Kang,H.J., Lee,Y.M., Jeong,M.S., Kim,M., Bae,K.H., Kim,S.J. and Chung,S.J.
    Molecular insight into the role of the leucine residue on the L2 loop in the catalytic activity of caspases 3 and 7
    Biosci Rep (2012) 32, 305-313. PubMed  Europe PubMed DOI
  60. Nguyen,Q.D., Challapalli,A., Smith,G., Fortt,R. and Aboagye,E.O.
    Imaging apoptosis with positron emission tomography: 'Bench to bedside' development of the caspase-3/7 specific radiotracer [(18)F]ICMT-11
    Eur J Cancer (2012) 48, 432-440. PubMed  Europe PubMed DOI  L
  61. Roschitzki-Voser,H., Schroeder,T., Lenherr,E.D., Frolich,F., Schweizer,A., Donepudi,M., Ganesan,R., Mittl,P.R., Baici,A. and Grutter,M.G.
    Human caspases in vitro: expression, purification and kinetic characterization
    Protein Expr Purif (2012) 84, 236-246. PubMed  Europe PubMed DOI  E
  62. Vanden Berghe,T., Kersse,K. and Vandenabeele,P.
    Caspase-3 and caspase-7
    [ISSN:978-0-12-407743-0] (2012) 3, 2256-2265. DOI
    63. 2011
  63. Boucher,D., Blais,V., Drag,M. and Denault,J.B.
    Molecular determinants involved in activation of caspase 7
    Biosci Rep (2011) 31, 283-294. PubMed  Europe PubMed DOI
  64. Burguillos,M.A., Deierborg,T., Kavanagh,E., Persson,A., Hajji,N., Garcia-Quintanilla,A., Cano,J., Brundin,P., Englund,E., Venero,J.L. and Joseph,B.
    Caspase signalling controls microglia activation and neurotoxicity
    Nature (2011) 472, 319-324. PubMed  Europe PubMed DOI
  65. Edelmann,B., Bertsch,U., Tchikov,V., Winoto-Morbach,S., Perrotta,C., Jakob,M., Adam-Klages,S., Kabelitz,D. and Schutze,S.
    Caspase-8 and caspase-7 sequentially mediate proteolytic activation of acid sphingomyelinase in TNF-R1 receptosomes
    EMBO J (2011) 30, 379-394. PubMed  Europe PubMed DOI  P
  66. Scabini,M., Stellari,F., Cappella,P., Rizzitano,S., Texido,G. and Pesenti,E.
    In vivo imaging of early stage apoptosis by measuring real-time caspase-3/7 activation
    Apoptosis (2011) 16, 198-207. PubMed  Europe PubMed DOI  L
  67. Soares,J., Lowe,M.M. and Jarstfer,M.B.
    The catalytic subunit of human telomerase is a unique caspase-6 and caspase-7 substrate
    Biochemistry (2011) 50, 9046-9055. PubMed  Europe PubMed DOI  P
  68. Witkowski,W.A. and Hardy,J.A.
    A designed redox-controlled caspase
    Protein Sci (2011) 20, 1421-1431. PubMed  Europe PubMed DOI
    69. 2010
  69. Gray,D.C., Mahrus,S. and Wells,J.A.
    Activation of specific apoptotic caspases with an engineered small-molecule-activated protease
    Cell (2010) 142, 637-646. PubMed  Europe PubMed DOI
  70. Lamkanfi,M. and Kanneganti,T.D.
    Caspase-7: a protease involved in apoptosis and inflammation
    Int J Biochem Cell Biol (2010) 42, 21-24. PubMed  Europe PubMed DOI  T
  71. Lee,Y.M., Kang,H.J., Jang,M., Kim,M., Bae,K.H. and Chung,S.J.
    Large-scale expression in Escherichia coli and efficient purification of precursor and active caspase-7 by introduction of thrombin cleavage sites
    Protein Expr Purif (2010) 69, 29-33. PubMed  Europe PubMed DOI  E
  72. Miscione,G.P., Calvaresi,M. and Bottoni,A.
    Computational evidence for the catalytic mechanism of caspase-7. A DFT investigation
    J Phys Chem B (2010) 114, 4637-4645. PubMed  Europe PubMed DOI
    73. 2009
  73. Agniswamy,J., Fang,B. and Weber,I.T.
    Conformational similarity in the activation of caspase-3 and -7 revealed by the unliganded and inhibited structures of caspase-7
    Apoptosis (2009) 14, 1135-1144. PubMed  Europe PubMed DOI  S
  74. Akhter,A., Gavrilin,M.A., Frantz,L., Washington,S., Ditty,C., Limoli,D., Day,C., Sarkar,A., Newland,C., Butchar,J., Marsh,C.B., Wewers,M.D., Tridandapani,S., Kanneganti,T.D. and Amer,A.O.
    Caspase-7 activation by the Nlrc4/Ipaf inflammasome restricts Legionella pneumophila infection
    PLoS Pathog (2009) 5, e1000361-e1000361. PubMed  Europe PubMed DOI  PMC  EPMC
  75. Alves,J., Wurdak,H., Garay-Malpartida,H.M., Harris,J.L., Occhiucci,J.M., Belizario,J.E. and Li,J.
    TAF15 and the leukemia-associated fusion protein TAF15-CIZ/NMP4 are cleaved by caspases-3 and -7
    Biochem Biophys Res Commun (2009) 384, 495-500. PubMed  Europe PubMed DOI  P
  76. Demon,D., Van Damme,P., Vanden Berghe,T., Deceuninck,A., Van Durme,J., Verspurten,J., Helsens,K., Impens,F., Wejda,M., Schymkowitz,J., Rousseau,F., Madder,A., Vandekerckhove,J., Declercq,W., Gevaert,K. and Vandenabeele,P.
    Proteome-wide substrate analysis indicates substrate exclusion as a mechanism to generate caspase-7 versus caspase-3 specificity
    Mol Cell Proteomics (2009) 8, 2700-2714. PubMed  Europe PubMed DOI  P
  77. Gafni,J., Cong,X., Chen,S.F., Gibson,B.W. and Ellerby,L.M.
    Calpain-1 cleaves and activates caspase-7
    J Biol Chem (2009) 284, 25441-25449. PubMed  Europe PubMed DOI  PMC  EPMC
  78. Hardy,J.A. and Wells,J.A.
    Dissecting an allosteric switch in caspase-7 using chemical and mutational probes
    J Biol Chem (2009) 284, 26063-26069. PubMed  Europe PubMed DOI  PMC  EPMC
  79. Lee,W.K., Kim,J.S., Kang,H.G., Cha,S.I., Kim,D.S., Hyun,D.S., Kam,S., Kim,C.H., Jung,T.H. and Park,J.Y.
    Polymorphisms in the caspase7 gene and the risk of lung cancer
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  80. Podichetty,A.K., Faust,A., Kopka,K., Wagner,S., Schober,O., Schafers,M. and Haufe,G.
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