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Literature for peptidase C13.007: legumain, trematode-type

Summary Alignment Tree Sequences Sequence features Distribution Literature Substrates

(Topics flags: S Structure, P Specificity, I Inhibitor, E Expression, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2024
  1. Ehsan,M., Hu,R.S., Wang,M., Hou,J.L., Rashid,M. and Malik,M.I.
    Immune modulation of goat monocytes by Fasciola gigantica Legumain-1 protein (Fg-LGMN-1)
    Exp Parasitol256, 108671-108671. PubMed  Europe PubMed DOI
  2. Wu,D.Q., Guo,Y.F., Zou,Y., Tang,X.T., Zhang,W.Y. and Di,W.D.
    Immune modulation of buffalo peripheral blood mononuclear cells by two asparaginyl endopeptidases from Fasciola gigantica
    Parasit Vectors17, 516-516. PubMed  Europe PubMed DOI
    3. 2020
  3. Corrigan,T.S., Lotti Diaz,L.M., Border,S.E., Ratigan,S.C., Kasper,K.Q., Sojka,D., Fajtova,P., Caffrey,C.R., Salvesen,G.S., McElroy,C.A., Hadad,C.M. and Dogan Ekici,O.
    Design, synthesis, and in vitro evaluation of aza-peptide aldehydes and ketones as novel and selective protease inhibitors
    J Enzyme Inhib Med Chem35, 1387-1402. PubMed  Europe PubMed DOI  I
    4. 2019
  4. Lorenzo,M.A., Gauna,A.N., Herrera,J., Bermudez,H., Losada,S., Noya,O. and Serrano,M.L.
    In silico modeling and structural analysis of asparaginyl endopeptidase of Schistosoma mansoni (Sm32): immunological and drug target implications
    Comput Biol Chem78, 18-27. PubMed  Europe PubMed DOI  S
    5. 2014
  5. Jilkova,A., Horn,M., Rezacova,P., Maresova,L., Fajtova,P., Brynda,J., Vondrasek,J., McKerrow,J.H., Caffrey,C.R. and Mares,M.
    Activation route of the Schistosoma mansoni cathepsin B1 drug target: structural map with a glycosaminoglycan switch
    Structure22, 1786-1798. PubMed  Europe PubMed DOI  S
    6. 2009
  6. Dalton,J.P., Brindley,P.J., Donnelly,S. and Robinson,M.W.
    The enigmatic asparaginyl endopeptidase of helminth parasites
    Trends Parasitol25, 59-61. PubMed  Europe PubMed DOI  V
  7. Ovat,A., Muindi,F., Fagan,C., Brouner,M., Hansell,E., Dvorak,J., Sojka,D., Kopacek,P., McKerrow,J.H., Caffrey,C.R. and Powers,J.C.
    Aza-peptidyl Michael acceptor and epoxide inhibitors - potent and selective inhibitors of Schistosoma mansoni and Ixodes ricinus legumains (asparaginyl endopeptidases)
    J Med Chem52, 7192-7210. PubMed  Europe PubMed DOI  I
    8. 2008
  8. Krautz-Peterson,G. and Skelly,P.J.
    Schistosome asparaginyl endopeptidase (legumain) is not essential for cathepsin B1 activation in vivo
    Mol Biochem Parasitol159, 54-58. PubMed  Europe PubMed DOI
  9. Laha,T., Sripa,J., Sripa,B., Pearson,M., Tribolet,L., Kaewkes,S., Sithithaworn,P., Brindley,P.J. and Loukas,A.
    Asparaginyl endopeptidase from the carcinogenic liver fluke, Opisthorchis viverrini, and its potential for serodiagnosis
    Int J Infect Dis12, e49-e59. PubMed  Europe PubMed DOI
    10. 2007
  10. Adisakwattana,P., Viyanant,V., Chaicumpa,W., Vichasri-Grams,S., Hofmann,A., Korge,G., Sobhon,P. and Grams,R.
    Comparative molecular analysis of two asparaginyl endopeptidases and encoding genes from Fasciola gigantica
    Mol Biochem Parasitol156, 102-116. PubMed  Europe PubMed DOI
    11. 2006
  11. Beckham,S.A., Law,R.H., Smooker,P.M., Quinsey,N.S., Caffrey,C.R., McKerrow,J.H., Pike,R.N. and Spithill,T.W.
    Production and processing of a recombinant Fasciola hepatica cathepsin B-like enzyme (FhcatB1) reveals potential processing mechanisms in the parasite
    Biol Chem387, 1053-1061. PubMed  Europe PubMed DOI
    12. 2005
  12. [YEAR:8-6-2005]Dvorak,J., Delcroix,M., Rossi,A., Vopalensky,V., Pospisek,M., Sedinova,M., Mikes,L., Sajid,M., Sali,A., McKerrow,J.H., Horak,P. and Caffrey,C.R.
    Multiple cathepsin B isoforms in schistosomula of Trichobilharzia regenti: identification, characterisation and putative role in migration and nutrition
    Int J Parasitol35, 895-910. PubMed  Europe PubMed DOI
    13. 2004
  13. Brindley,P.J. and Dalton,J.P.
    Schistosome legumain
    [ISSN:0-12-079610-4]2, 1305-1310.  V
    14. 2003
  14. [YEAR:8-9-2003]Chacon,N., Losada,S., Bermudez,H., Cesari,I.M., Hoebeke,J. and Noya,O.
    Immunogenicity of polymerizable synthetic peptides derived from a vaccine candidate against schistosomiasis: the asparaginyl endopeptidase (Sm32)
    Immunol Lett88, 199-210. PubMed  Europe PubMed DOI
  15. James,K.E., Gotz,M.G., Caffrey,C.R., Hansell,E., Carter,W., Barrett,A.J., McKerrow,J.H. and Powers,J.C.
    Aza-peptide epoxides: potent and selective inhibitors of Schistosoma mansoni and pig kidney legumains (asparaginyl endopeptidases)
    Biol Chem384, 1613-1618. PubMed  Europe PubMed DOI  I
  16. [YEAR:8-9-2003]Noya,O., Alarcon de Noya,B., Guzman,F. and Bermudez,H.
    Immunogenicity of Sm32 synthetic peptides derived from the Schistosoma mansoni adult worm
    Immunol Lett88, 211-219. PubMed  Europe PubMed DOI
    17. 2002
  17. [YEAR:30-4-2002]Mathieu,M.A., Bogyo,M., Caffrey,C.R., Choe,Y., Lee,J., Chapman,H., Sajid,M., Craik,C.S. and McKerrow,J.H.
    Substrate specificity of schistosome versus human legumain determined by P1-P3 peptide libraries
    Mol Biochem Parasitol121, 99-105. PubMed  Europe PubMed DOI  P
    18. 2001
  18. [YEAR:12-11-2001]Chlichlia,K., Bahgat,M., Ruppel,A. and Schirrmacher,V.
    DNA vaccination with asparaginyl endopeptidase (Sm32) from the parasite Schistosoma mansoni: anti-fecundity effect induced in mice
    Vaccine20, 439-447. PubMed  Europe PubMed DOI
  19. Skelly,P.J. and Shoemaker,C.B.
    Schistosoma mansoni proteases Sm31 (cathepsin B) and Sm32 (legumain) are expressed in the cecum and protonephridia of cercariae
    J Parasitol87, 1218-1221. PubMed  Europe PubMed DOI
    20. 2000
  20. [YEAR:28-1-2000]Caffrey,C.R., Mathieu,M.A., Gaffney,A.M., Salter,J.P., Sajid,M., Lucas,K.D., Franklin,C., Bogyo,M. and McKerrow,J.H.
    Identification of a cDNA encoding an active asparaginyl endopeptidase of Schistosoma mansoni and its expression in Pichia pastoris
    FEBS Lett466, 244-248. PubMed  Europe PubMed DOI  E
    21. 1998
  21. El-Sayed,L.H., Ghoneim,H., Demian,S.R., El-Sayed,M.H., Tawfik,N.M., Sakr,I., Abou-Basha,L.M., Renganathan,E., Klinkert,M.Q. and Abou-Rawash,N.
    Diagnostic significance of Schistosoma mansoni proteins Sm31 and Sm32 in human schistosomiasis in an endemic area in Egypt
    Trop Med Int Health3, 721-727. PubMed  Europe PubMed DOI
    22. 1997
  22. Brindley,P.J., Kalinna,B.H., Dalton,J.P., Day,S.R., Wong,J.Y., Smythe,M.L. and McManus,D.P.
    Proteolytic degradation of host hemoglobin by schistosomes
    Mol Biochem Parasitol89, 1-9. PubMed  Europe PubMed DOI
    23. 1995
  23. Dalton,J.P., Hola-Jamriska,L. and Brindley,P.J.
    Asparaginyl endopeptidase activity in adult Schistosoma mansoni
    Parasitology111, 575-580. PubMed  Europe PubMed
  24. Tkalcevic,J., Ashman,K. and Meeusen,E.
    Fasciola hepatica: rapid identification of newly excysted juvenile proteins
    Biochem Biophys Res Commun213, 169-174. PubMed  Europe PubMed DOI
    25. 1990
  25. el Meanawy,M.A., Aji,T., Phillips,N.F., Davis,R.E., Salata,R.A., Malhotra,I., McClain,D., Aikawa,M. and Davis,A.H.
    Definition of the complete Schistosoma mansoni hemoglobinase mRNA sequence and gene expression in developing parasites
    Am J Trop Med Hyg43, 67-78. PubMed  Europe PubMed
    26. 1989
  26. Klinkert,M.Q., Felleisen,R., Link,G., Ruppel,A. and Beck,E.
    Primary structures of Sm31/32 diagnostic proteins of Schistosoma mansoni and their identification as proteases
    Mol Biochem Parasitol33, 113-122. PubMed  Europe PubMed
    27. 1987
  27. Ruppel,A., Shi,Y.E., Wei,D.X. and Diesfeld,H.J.
    Sera of Schistosoma japonicum-infected patients cross-react with diagnostic 31/32 kD proteins of S. mansoni
    Clin Exp Immunol69, 291-298. PubMed  Europe PubMed

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