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Literature for peptidase C02.004: calpain-3

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

(Topics flags: S Structure, P Specificity, K Knockout, E Expression, V Review, M Mutation, I Inhibitor, R Splicing, U Therapeutic. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Hisatsune,C., Shinkai-Ouchi,F., Hata,S. and Ono,Y.<br>In situ detection of activation of CAPN3, a responsible gene product for LGMDR1, in mouse skeletal myotubes<br>J Biol Chem (2025) , 108536-108536. PubMed  Europe PubMed DOI
    2. 2024
  2. Mao,B., Yang,J., Zhao,X., Jia,X., Shi,X., Zhao,L., Banerjee,S., Zhang,L. and Ma,X.<br>Identification and functional characterization of a novel heterozygous spliceƒ_'site mutation in the calpain 3 gene causes rare autosomal dominant limbƒ_'girdle muscular dystrophy<br>Exp Ther Med (2024) 27, 97-97. PubMed  Europe PubMed DOI  PMC  EPMC
  3. Valls,A., Gutierrez-Gutierrez,G., Martinez,A., Ruiz-Roldan,C., Camano,P., Lopez de Munain,A. and Saenz,A.<br>The CAPN3 p.Lys 254del variant is not always associated with dominant CAPN3-related muscular dystrophy<br>Muscle Nerve (2024) 69, 472-476. PubMed  Europe PubMed DOI
  4. Villani,K.R., Zhong,R., Henley-Beasley,C.S., Rastelli,G., Harris,E., Boncompagni,S., Barton,E.R. and Wei-LaPierre,L.<br>Loss of Calpain 3 dysregulates store-operated calcium entry and its exercise response in mice<br>FASEB J (2024) 38, e23825-e23825. PubMed  Europe PubMed DOI
  5. Ye,Q., Henrickson,A., Demeler,B., Balasco Serrao,V.H. and Davies,P.L.<br>Human calpain-3 and its structural plasticity: dissociation of a homohexamer into dimers on binding titin<br>J Biol Chem (2024) , 108133-108133. PubMed  Europe PubMed DOI
    6. 2023
  6. Joseph,R., Robinson,M.L., Lambert,L. and Srivastava,O.P.<br>Lens-specific betaA3/A1-conditional knockout mice: Phenotypic characteristics and calpain activation causing protein degradation and insolubilization<br>PLoS ONE (2023) 18, e0281386-e0281386. PubMed  Europe PubMed DOI  PMC  EPMC
  7. Ojima,K., Hata,S., Shinkai-Ouchi,F., Ono,Y. and Muroya,S.<br>Calpain-3 not only proteolyzes calpain-1 and -2 but also is a substrate for calpain-1 and -2<br>J Biochem (2023) 174, 421-431. PubMed  Europe PubMed DOI
  8. Wette,S.G., Lamb,G.D. and Murphy,R.M.<br>Calpain-3 Is Not a Sodium Dependent Protease and Simply Requires Calcium for Activation<br>Int J Mol Sci (2023) 24 PubMed  Europe PubMed DOI  PMC  EPMC
    9. 2022
  9. Ding,F., Huang,D., Wang,M. and Peng,J.<br>An 86 amino acids motif in CAPN3 is essential for formation of the nucleolus-localized Def-CAPN3 complex<br>Biochem Biophys Res Commun (2022) 623, 66-73. PubMed  Europe PubMed DOI
  10. Mroczek,M., Inashkina,I., Stavusis,J., Zayakin,P., Khrunin,A., Micule,I., Kenina,V., Zdanovica,A., Zidkova,J., Fajkusova,L., Limborska,S., van der Kooi,A.J., Brusse,E., Leonardis,L., Maver,A., Pajusalu,S., Ounap,K., Puusepp,S., Dobosz,P., Sypniewski,M., Burnyte,B. and Lace,B.<br>CAPN3 c.1746-20C>G variant is hypomorphic for LGMD R1 calpain 3-related<br>Hum Mutat (2022) 43, 1347-1353. PubMed  Europe PubMed DOI
    11. 2021
  11. Chen,L., Tang,F., Gao,H., Zhang,X., Li,X. and Xiao,D.<br>CAPN3: A musclespecific calpain with an important role in the pathogenesis of diseases (Review)<br>Int J Mol Med (2021) 48 PubMed  Europe PubMed DOI  PMC  EPMC  V
    12. 2020
  12. Hata,S., Doi,N., Shinkai-Ouchi,F. and Ono,Y.<br>A muscle-specific calpain, CAPN3, forms a homotrimer<br>Biochim Biophys Acta Proteins Proteom (2020) 1868, 140411-140411. PubMed  Europe PubMed DOI  S
  13. Huang,W., Chen,F., Ma,Q., Xin,J., Li,J., Chen,J., Zhou,B., Chen,M., Li,J. and Peng,J.<br>Ribosome biogenesis gene DEF/UTP25 is essential for liver homeostasis and regeneration<br>Sci China Life Sci (2020) PubMed  Europe PubMed DOI  K
  14. Hwang,S.D., Choi,K.M., Hwang,J.Y., Kwon,M.G., Jeong,J.M., Seo,J.S., Jee,B.Y. and Park,C.I.<br>Molecular genetic characterisation and expression profiling of calpain 3 transcripts in red sea bream (Pagrus major)<br>Fish Shellfish Immunol (2020) 98, 19-24. PubMed  Europe PubMed DOI
  15. Jahnke,V.E., Peterson,J.M., Van Der Meulen,J.H., Boehler,J., Uaesoontrachoon,K., Johnston,H.K., Defour,A., Phadke,A., Yu,Q., Jaiswal,J.K. and Nagaraju,K.<br>Mitochondrial dysfunction and consequences in calpain-3-deficient muscle<br>Skelet Muscle (2020) 10, 37-37. PubMed  Europe PubMed DOI  PMC  EPMC
  16. Landires,I., Nunez-Samudio,V., Fernandez,J., Sarria,C., Villareal,V., Cordoba,F., Apraez-Ippolito,G., Martinez,S., Vidal,O.M., Velez,J.I., Arcos-Holzinger,M., Landires,S. and Arcos-Burgos,M.<br>Calpainopathy: Description of a Novel Mutation and Clinical Presentation with Early Severe Contractures<br>Genes (Basel) (2020) 11 PubMed  Europe PubMed DOI  M
  17. Vissing,J., Dahlqvist,J.R., Roudaut,C., Poupiot,J., Richard,I., Duno,M. and Krag,T.<br>A single c.1715G>C calpain 3 gene variant causes dominant calpainopathy with loss of calpain 3 expression and activity<br>Hum Mutat (2020) 41, 1507-1513. PubMed  Europe PubMed DOI
    18. 2019
  18. El-Khoury,R., Traboulsi,S., Hamad,T., Lamaa,M., Sawaya,R. and Ahdab-Barmada,M.<br>Divergent features of mitochondrial deficiencies in LGMD2A associated with novel calpain-3 mutations<br>J Neuropathol Exp Neurol (2019) 78, 88-98. PubMed  Europe PubMed DOI  M
  19. Lostal,W., Roudaut,C., Faivre,M., Charton,K., Suel,L., Bourg,N., Best,H., Smith,J.E., Gohlke,J., Corre,G., Li,X., Elbeck,Z., Knoll,R., Deschamps,J.Y., Granzier,H. and Richard,I.<br>Titin splicing regulates cardiotoxicity associated with calpain 3 gene therapy for limb-girdle muscular dystrophy type 2A<br>Sci Transl Med (2019) 11 PubMed  Europe PubMed DOI  U
    20. 2018
  20. McCartney,C.E., Ye,Q., Campbell,R.L. and Davies,P.L.<br>Insertion sequence 1 from calpain-3 is functional in calpain-2 as an internal propeptide<br>J Biol Chem (2018) 293, 17716-17730. PubMed  Europe PubMed DOI
  21. Ye,Q., Campbell,R.L. and Davies,P.L.<br>Structures of human calpain-3 protease core with and without bound inhibitor reveal mechanisms of calpain activation<br>J Biol Chem (2018) 293, 4056-4070. PubMed  Europe PubMed DOI  S  I
    22. 2017
  22. Pantoja-Melendez,C.A., Miranda-Duarte,A., Roque-Ramirez,B. and Zenteno,J.C.<br>Epidemiological and molecular characterization of a Mexican population isolate with high prevalence of limb-girdle muscular dystrophy Type 2A due to a novel calpain-3 mutation<br>PLoS ONE (2017) 12, e0170280-e0170280. PubMed  Europe PubMed DOI  M
    23. 2016
  23. Fadaee,M., Kariminejad,A., Fattahi,Z., Nafissi,S., Godarzi,H.R., Beheshtian,M., Vazehan,R., Akbari,M.R., Kahrizi,K. and Najmabadi,H.<br>Report of limb girdle muscular dystrophy type 2a in 6 Iranian patients, one with a novel deletion in CAPN3 gene<br>Neuromuscul Disord (2016) 26, 277-282. PubMed  Europe PubMed DOI  M
  24. Michel,L.Y., Hoenderop,J.G. and Bindels,R.J.<br>Calpain-3-mediated regulation of the Na(+)-Ca(2+) exchanger isoform 3<br>Pflugers Arch (2016) 468, 243-255. PubMed  Europe PubMed DOI
  25. Ono,Y., Ojima,K., Shinkai-Ouchi,F., Hata,S. and Sorimachi,H.<br>An eccentric calpain, CAPN3/p94/calpain-3<br>Biochimie (2016) 122, 169-187. PubMed  Europe PubMed DOI  V
  26. Richard,I., Hogrel,J.Y., Stockholm,D., Payan,C.A., Fougerousse,F., Eymard,B., Mignard,C., Lopez de Munain,A., Fardeau,M. and Urtizberea,J.A.<br>Natural history of LGMD2A for delineating outcome measures in clinical trials<br>Ann Clin Transl Neurol (2016) 3, 248-265. PubMed  Europe PubMed DOI  PMC  EPMC  M
    27. 2015
  27. Dorobek,M., Ryniewicz,B., Kabzinska,D., Fidzianska,A., Styczynska,M. and Hausmanowa-Petrusewicz,I.<br>The frequency of c.550delA mutation of the CANP3 gene in the Polish LGMD2A population<br>Genet Test Mol Biomarkers (2015) 19, 637-640. PubMed  Europe PubMed DOI  M
  28. Ermolova,N., Kramerova,I. and Spencer,M.J.<br>Autolytic activation of calpain 3 proteinase is facilitated by calmodulin protein<br>J Biol Chem (2015) 290, 996-1004. PubMed  Europe PubMed DOI
  29. Muto,Y., Morton,J. and Palmer,D.<br>Investigation of biochemical changes of the ovine calpain 3 exon-10 polymorphism<br>Mol Cell Probes (2015) 29, 382-388. PubMed  Europe PubMed DOI  M
  30. Ono,Y. and Sorimachi,H.<br>Amino acid sequence alignment of vertebrate CAPN3/calpain-3/p94<br>Data Brief (2015) 5, 366-367. PubMed  Europe PubMed DOI
  31. Ramos,E., Pardo,S., Mas Rodriguez,M.F. and Velez,J.<br>Limb-girdle muscular dystrophy type 2A resulting from c.C479G and c.G1818A mutations in the calpain-3 gene<br>J Clin Neuromuscul Dis (2015) 17, 59-62. PubMed  Europe PubMed DOI  M
  32. Ramos,E., Pardo,S., Mas,R.M.F. and Velez,J.<br>Limb-girdle muscular dystrophy type 2A resulting from c.C479G and c.G1818A mutations in the calpain-3 gene<br>J Clin Neuromuscul Dis (2015) 17, 59-62.  M
    33. 2014
  33. Kanzaki,K., Kuratani,M., Matsunaga,S., Yanaka,N. and Wada,M.<br>Three calpain isoforms are autolyzed in rat fast-twitch muscle after eccentric contractions<br>J Muscle Res Cell Motil (2014) 35, 179-189. PubMed  Europe PubMed DOI
  34. Nakajima,T., Shearer,T.R. and Azuma,M.<br>Loss of calpastatin leads to activation of calpain in human lens epithelial cells<br>Invest Ophthalmol Vis Sci (2014) 55, 5278-5283. PubMed  Europe PubMed DOI  I
  35. Ojima,K., Ono,Y., Hata,S., Noguchi,S., Nishino,I. and Sorimachi,H.<br>Muscle-specific calpain-3 is phosphorylated in its unique insertion region for enrichment in a myofibril fraction<br>Genes Cells (2014) 19, 830-841. PubMed  Europe PubMed DOI
  36. Ono,Y., Shindo,M., Doi,N., Kitamura,F., Gregorio,C.C. and Sorimachi,H.<br>The N- and C-terminal autolytic fragments of CAPN3/p94/calpain-3 restore proteolytic activity by intermolecular complementation<br>Proc Natl Acad Sci U S A (2014) 111, E5527-E5536. PubMed  Europe PubMed DOI
  37. Partha,S.K., Ravulapalli,R., Allingham,J.S., Campbell,R.L. and Davies,P.L.<br>Crystal structure of calpain-3 penta-EF-hand (PEF) domain - a homodimerized PEF family member with calcium bound at the fifth EF-hand<br>FEBS J (2014) 281, 3138-3149. PubMed  Europe PubMed DOI  S
    38. 2013
  38. Fang,Q., Forrest,R.H., Zhou,H., Frampton,C.M. and Hickford,J.G.<br>Variation in exon 10 of the ovine calpain 3 gene (CAPN3) and its association with meat yield in New Zealand Romney sheep<br>Meat Sci (2013) 94, 388-390. PubMed  Europe PubMed DOI  M
  39. Nuaaman,M.M. and Benchimol,S.<br>Proteasome-independent p53 degradation<br>Cell Res (2013) 23, 597-598. PubMed  Europe PubMed DOI
  40. Ono,Y., Iemura,S., Novak,S.M., Doi,N., Kitamura,F., Natsume,T., Gregorio,C.C. and Sorimachi,H.<br>PLEIAD/SIMC1/C5orf25, a novel autolysis regulator for a skeletal-muscle-specific calpain, CAPN3, scaffolds a CAPN3 substrate, CTBP1<br>J Mol Biol (2013) 425, 2955-2972. PubMed  Europe PubMed DOI
  41. Tao,T., Shi,H., Guan,Y., Huang,D., Chen,Y., Lane,D.P., Chen,J. and Peng,J.<br>Def defines a conserved nucleolar pathway that leads p53 to proteasome-independent degradation<br>Cell Res (2013) 23, 620-634. PubMed  Europe PubMed DOI
    42. 2012
  42. Sorimachi,H., Hata,S. and Ono,Y.<br>Muscle calpain<br>[ISSN:978-0-12-407743-0] (2012) 3, 2011-2017. DOI
  43. Sorimachi,H. and Ono,Y.<br>Regulation and physiological roles of the calpain system in muscular disorders<br>Cardiovasc Res (2012) 96, 11-22. PubMed  Europe PubMed DOI  PMC  EPMC  V
    44. 2011
  44. Gallardo,E., Saenz,A. and Illa,I.<br>Limb-girdle muscular dystrophy 2A<br>Handb Clin Neurol (2011) 101, 97-110. PubMed  Europe PubMed DOI  M  V
  45. Murphy,R.M., Vissing,K., Latchman,H., Lamboley,C., McKenna,M.J., Overgaard,K. and Lamb,G.D.<br>Activation of skeletal muscle calpain-3 by eccentric exercise in humans does not result in its translocation to the nucleus or cytosol<br>J Appl Physiol (2011) 111, 1448-1458. PubMed  Europe PubMed DOI
  46. Ojima,K., Ono,Y., Ottenheijm,C., Hata,S., Suzuki,H., Granzier,H. and Sorimachi,H.<br>Non-proteolytic functions of calpain-3 in sarcoplasmic reticulum in skeletal muscles<br>J Mol Biol (2011) 407, 439-449. PubMed  Europe PubMed DOI
  47. Saenz,A., Ono,Y., Sorimachi,H., Goicoechea,M., Leturcq,F., Blazquez,L., Garcia-Bragado,F., Marina,A., Poza,J.J., Azpitarte,M., Doi,N., Urtasun,M., Kaplan,J.C. and De Munain,A.L.<br>Does the severity of the LGMD2A phenotype in compound heterozygotes depend on the combination of mutations?<br>Muscle Nerve (2011) 44, 710-714. PubMed  Europe PubMed DOI  M
    48. 2010
  48. Charton,K., Daniele,N., Vihola,A., Roudaut,C., Gicquel,E., Monjaret,F., Tarrade,A., Sarparanta,J., Udd,B. and Richard,I.<br>Removal of the calpain 3 protease reverses the myopathology in a mouse model for titinopathies<br>Hum Mol Genet (2010) 19, 4608-4624. PubMed  Europe PubMed DOI
  49. de Morree,A., Lutje Hulsik,D., Impagliazzo,A., van Haagen,H.H., de Galan,P., van Remoortere,A., 't Hoen,P.A., van Ommen,G.B., Frants,R.R. and van der Maarel,S.M.<br>Calpain 3 is a rapid-action, unidirectional proteolytic switch central to muscle remodeling<br>PLoS ONE (2010) 5, e11940-e11940. PubMed  Europe PubMed DOI  PMC  EPMC
  50. Laure,L., Daniele,N., Suel,L., Marchand,S., Aubert,S., Bourg,N., Roudaut,C., Duguez,S., Bartoli,M. and Richard,I.<br>A new pathway encompassing calpain 3 and its newly identified substrate cardiac ankyrin repeat protein is involved in the regulation of the nuclear factor-kappaB pathway in skeletal muscle<br>FEBS J (2010) 277, 4322-4337. PubMed  Europe PubMed DOI
  51. Ojima,K., Kawabata,Y., Nakao,H., Nakao,K., Doi,N., Kitamura,F., Ono,Y., Hata,S., Suzuki,H., Kawahara,H., Bogomolovas,J., Witt,C., Ottenheijm,C., Labeit,S., Granzier,H., Toyama-Sorimachi,N., Sorimachi,M., Suzuki,K., Maeda,T., Abe,K., Aiba,A. and Sorimachi,H.<br>Dynamic distribution of muscle-specific calpain in mice has a key role in physical-stress adaptation and is impaired in muscular dystrophy<br>J Clin Invest (2010) 120, 2672-2683. PubMed  Europe PubMed DOI
  52. Ono,Y., Ojima,K., Torii,F., Takaya,E., Doi,N., Nakagawa,K., Hata,S., Abe,K. and Sorimachi,H.<br>Skeletal muscle-specific calpain is an intracellular Na+-dependent protease<br>J Biol Chem (2010) 285, 22986-22998. PubMed  Europe PubMed DOI
  53. Stuelsatz,P., Pouzoulet,F., Lamarre,Y., Dargelos,E., Poussard,S., Leibovitch,S., Cottin,P. and Veschambre,P.<br>Down-regulation of MyoD by calpain 3 promotes generation of reserve cells in C2C12 myoblasts<br>J Biol Chem (2010) 285, 12670-12683. PubMed  Europe PubMed DOI
    54. 2009
  54. Bertipaglia,I., Bourg,N., Richard,I., Pahlman,A.K., Andersson,L., James,P. and Carafoli,E.<br>A proteomic study of calpain-3 and its involvement in limb girdle muscular dystrophy type 2a<br>Cell Calcium (2009) 46, 356-363. PubMed  Europe PubMed DOI  P
  55. Garnham,C.P., Hanna,R.A., Chou,J.S., Low,K.E., Gourlay,K., Campbell,R.L., Beckmann,J.S. and Davies,P.L.<br>Limb-girdle muscular dystrophy type 2A can result from accelerated autoproteolytic inactivation of calpain 3<br>Biochemistry (2009) 48, 3457-3467. PubMed  Europe PubMed DOI
  56. Kramerova,I., Kudryashova,E., Wu,B., Germain,S., Vandenborne,K., Romain,N., Haller,R.G., Verity,M.A. and Spencer,M.J.<br>Mitochondrial abnormalities, energy deficit and oxidative stress are features of calpain 3 deficiency in skeletal muscle<br>Hum Mol Genet (2009) 18, 3194-3205. PubMed  Europe PubMed DOI  PMC  EPMC  M
  57. Moretti,D., Del Bello,B., Cosci,E., Biagioli,M., Miracco,C. and Maellaro,E.<br>Novel variants of muscle calpain 3 identified in human melanoma cells: cisplatin-induced changes in vitro and differential expression in melanocytic lesions<br>Carcinogenesis (2009) 30, 960-967. PubMed  Europe PubMed DOI  R
  58. Vattemi,G., Tonin,P., Neri,M., Marini,M., Gualandi,F., Guglielmi,V., Ferlini,A. and Tomelleri,G.<br>Calpain 3 deficiency presenting as fibre type disproportion<br>Neuropathol Appl Neurobiol (2009) 35, 614-617. PubMed  Europe PubMed DOI  M
    59. 2008
  59. Barendse,W., Harrison,B.E., Bunch,R.J. and Thomas,M.B.<br>Variation at the calpain 3 gene is associated with meat tenderness in zebu and composite breeds of cattle<br>BMC Genet (2008) 9, 41-41. PubMed  Europe PubMed DOI  PMC  EPMC  M
  60. Beckmann,J.S. and Spencer,M.<br>Calpain 3, the "gatekeeper" of proper sarcomere assembly, turnover and maintenance<br>Neuromuscul Disord (2008) 18, 913-921. PubMed  Europe PubMed DOI  PMC  EPMC  V
  61. Benayoun,B., Baghdiguian,S., Lajmanovich,A., Bartoli,M., Daniele,N., Gicquel,E., Bourg,N., Raynaud,F., Pasquier,M.A., Suel,L., Lochmuller,H., Lefranc,G. and Richard,I.<br>NF-kappaB-dependent expression of the antiapoptotic factor c-FLIP is regulated by calpain 3, the protein involved in limb-girdle muscular dystrophy type 2A<br>FASEB J (2008) 22, 1521-1529. PubMed  Europe PubMed DOI
  62. Hayashi,C., Ono,Y., Doi,N., Kitamura,F., Tagami,M., Mineki,R., Arai,T., Taguchi,H., Yanagida,M., Hirner,S., Labeit,D., Labeit,S. and Sorimachi,H.<br>Multiple molecular interactions implicate the connectin/titin N2A region as a modulating scaffold for p94/calpain 3 activity in skeletal muscle<br>J Biol Chem (2008) 283, 14801-14814. PubMed  Europe PubMed DOI
  63. Kramerova,I., Kudryashova,E., Wu,B., Ottenheijm,C., Granzier,H. and Spencer,M.J.<br>Novel role of calpain-3 in the triad-associated protein complex regulating calcium release in skeletal muscle<br>Hum Mol Genet (2008) 17, 3271-3280. PubMed  Europe PubMed DOI  PMC  EPMC
  64. Ono,Y., Hayashi,C., Doi,N., Tagami,M. and Sorimachi,H.<br>The importance of conserved amino acid residues in p94 protease sub-domain IIb and the IS2 region for constitutive autolysis<br>FEBS Lett (2008) 582, 691-698. PubMed  Europe PubMed DOI
    65. 2007
  65. Chung,H., Choi,B., Jang,G., Lee,K., Kim,H., Yoon,S., Im,S., Davis,M. and Hines,H.<br>Effect of variants in the ovine skeletal-muscle-specific calpain gene on body weight<br>J Appl Genet (2007) 48, 61-68. PubMed  Europe PubMed  M
  66. Fanin,M., Nascimbeni,A.C. and Angelini,C.<br>Screening of calpain-3 autolytic activity in lgmd muscle: a functional map of capn3 gene mutations<br>J Med Genet (2007) 44, 38-43. PubMed  Europe PubMed DOI
  67. Hanisch,F., Muller,C.R., Grimm,D., Xue,L., Traufeller,K., Merkenschlager,A., Zierz,S. and Deschauer,M.<br>Frequency of calpain-3 c.550delA mutation in limb girdle muscular dystrophy type 2 and isolated hyperCKemia in German patients<br>Clin Neuropathol (2007) 26, 157-163. PubMed  Europe PubMed  M
  68. Kramerova,I., Beckmann,J.S. and Spencer,M.J.<br>Molecular and cellular basis of calpainopathy (limb girdle muscular dystrophy type 2A)<br>Biochim Biophys Acta (2007) 1772, 128-144. PubMed  Europe PubMed DOI  V
  69. Milic,A., Daniele,N., Lochmuller,H., Mora,M., Comi,G.P., Moggio,M., Noulet,F., Walter,M.C., Morandi,L., Poupiot,J., Roudaut,C., Bittner,R.E., Bartoli,M. and Richard,I.<br>A third of LGMD2A biopsies have normal calpain 3 proteolytic activity as determined by an in vitro assay<br>Neuromuscul Disord (2007) 17, 148-156. PubMed  Europe PubMed DOI
  70. Ojima,K., Ono,Y., Doi,N., Yoshioka,K., Kawabata,Y., Labeit,S. and Sorimachi,H.<br>Myogenic stage, sarcomere length, and protease activity modulate localization of muscle-specific calpain<br>J Biol Chem (2007) 282, 14493-14504. PubMed  Europe PubMed DOI
  71. Ono,Y., Hayashi,C., Doi,N., Kitamura,F., Shindo,M., Kudo,K., Tsubata,T., Yanagida,M. and Sorimachi,H.<br>Comprehensive survey of p94/calpain 3 substrates by comparative proteomics - possible regulation of protein synthesis by p94<br>Biotechnol J (2007) 2, 565-576. PubMed  Europe PubMed DOI
  72. Tang,Y., Liu,X., Zoltoski,R.K., Novak,L.A., Herrera,R.A., Richard,I., Kuszak,J.R. and Kumar,N.M.<br>Age-related cataracts in alpha3Cx46-knockout mice are dependent on a calpain 3 isoform<br>Invest Ophthalmol Vis Sci (2007) 48, 2685-2694. PubMed  Europe PubMed DOI  PMC  EPMC
  73. Zhou,H., Hickford,J.G. and Fang,Q.<br>Single nucleotide polymorphisms of the ovine calpain 3 (CAPN3) gene<br>Mol Cell Probes (2007) 21, 78-79. PubMed  Europe PubMed DOI  M
    74. 2006
  74. [YEAR:13-1-2006]Balci,B., Aurino,S., Haliloglu,G., Talim,B., Erdem,S., Akcoren,Z., Tan,E., Caglar,M., Richard,I., Nigro,V., Topaloglu,H. and Dincer,P.<br>Calpain-3 mutations in Turkey<br>Eur J Pediatr (13-1-2006) 165, 293-298. PubMed  Europe PubMed DOI  M
  75. [YEAR:19-10-2006]Cohen,N., Kudryashova,E., Kramerova,I., Anderson,L.V., Beckmann,J.S., Bushby,K. and Spencer,M.J.<br>Identification of putative in vivo substrates of calpain 3 by comparative proteomics of overexpressing transgenic and nontransgenic mice<br>Proteomics (19-10-2006) 6, 6075-6084. PubMed  Europe PubMed DOI
  76. Duguez,S., Bartoli,M. and Richard,I.<br>Calpain 3: a key regulator of the sarcomere?<br>FEBS J (2006) 273, 3427-3436. PubMed  Europe PubMed DOI
  77. [YEAR:21-3-2006]Garcia Diaz,B.E., Gauthier,S. and Davies,P.L.<br>Ca2+ dependency of calpain 3 (p94) activation<br>Biochemistry (21-3-2006) 45, 3714-3722. PubMed  Europe PubMed DOI
  78. Koohmaraie,M. and Geesink,G.H.<br>Contribution of postmortem muscle biochemistry to the delivery of consistent meat quality with particular focus on the calpain system<br>Meat Sci (2006) 74, 34-43. PubMed  Europe PubMed DOI
  79. Kramerova,I., Kudryashova,E., Wu,B. and Spencer,M.J.<br>Regulation of the M-cadherin-beta-catenin complex by calpain 3 during terminal stages of myogenic differentiation<br>Mol Cell Biol (2006) 26, 8437-8447. PubMed  Europe PubMed DOI  PMC  EPMC
  80. [YEAR:26-7-2006]Shih,M., Ma,H., Nakajima,E., David,L.L., Azuma,M. and Shearer,T.R.<br>Biochemical properties of lens-specific calpain Lp85<br>Exp Eye Res (26-7-2006) 82, 146-152. PubMed  Europe PubMed DOI  R
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