Literature for peptidase C01.149: TgCPL peptidase (Toxoplasma-type)

(Topics flags: I Inhibitor. To select only the references relevant to a single topic, click the link above. See explanation.)

2025
1. Rimple,P.A., Olafsson,E.B., Markus,B.M., Wang,F., Augusto,L., Lourido,S. and Carruthers,V.B.
   Metabolic adaptability and nutrient scavenging in Toxoplasma gondii: insights from ingestion pathway-deficient mutants
   mSpheree0101124-e0101124. PubMed  Europe PubMed DOI
2020
2. Zwicker,J.D., Smith,D., Guerra,A.J., Hitchens,J.R., Haug,N., Vander Roest,S., Lee,P., Wen,B., Sun,D., Wang,L., Keep,R., Xiang,J., Carruthers,V.B. and Larsen,S.D.
   Discovery and optimization of triazine nitrile inhibitors of Toxoplasma gondii cathepsin L for the potential treatment of chronic toxoplasmosis in the CNS
   ACS Chem Neurosci11, 2450-2463. PubMed  Europe PubMed DOI  I
2018
3. Zwicker,J.D., Diaz,N.A., Guerra,A.J., Kirchhoff,P.D., Wen,B., Sun,D., Carruthers,V.B. and Larsen,S.D.
   Optimization of dipeptidic inhibitors of cathepsin L for improved Toxoplasma gondii selectivity and CNS permeability
   Bioorg Med Chem Lett28, 1972-1980. PubMed  Europe PubMed DOI  I
2014
4. Coppens,I.
   Toxoplasma, or the discovery of a heterophage
   Trends Parasitol30, 467-469. PubMed  Europe PubMed DOI
5. Dou,Z., McGovern,O.L., Di Cristina,M. and Carruthers,V.B.
   Toxoplasma gondii ingests and digests host cytosolic proteins
   MBio5, e01188-e01114. PubMed  Europe PubMed DOI
2013
6. Dou,Z., Coppens,I. and Carruthers,V.B.
   Non-canonical maturation of two papain-family proteases in Toxoplasma gondii
   J Biol Chem288, 3523-3534. PubMed  Europe PubMed DOI
2012
7. Dou,Z. and Carruthers,V.B.
   Toxoplasma gondii cathepsin L-like protease, TgCPL
   [ISSN:978-0-12-407743-0]3, 1929-1933. DOI
2011
8. Dou,Z. and Carruthers,V.B.
   Cathepsin proteases in Toxoplasma gondii
   Adv Exp Med Biol712, 49-61. PubMed  Europe PubMed DOI  I
2010
9. Parussini,F., Coppens,I., Shah,P.P., Diamond,S.L. and Carruthers,V.B.
   Cathepsin L occupies a vacuolar compartment and is a protein maturase within the endo/exocytic system of Toxoplasma gondii
   Mol Microbiol76, 1340-1357. PubMed  Europe PubMed DOI
2009
10. Huang,R., Que,X., Hirata,K., Brinen,L.S., Lee,J.H., Hansell,E., Engel,J., Sajid,M. and Reed,S.
    The cathepsin L of Toxoplasma gondii (TgCPL) and its endogenous macromolecular inhibitor, toxostatin
    Mol Biochem Parasitol164, 86-94. PubMed  Europe PubMed DOI
11. Larson,E.T., Parussini,F., Huynh,M.H., Giebel,J.D., Kelley,A.M., Zhang,L., Bogyo,M., Merritt,E.A. and Carruthers,V.B.
    Toxoplasma gondii cathepsin L is the primary target of the invasion-inhibitory compound morpholinurea-leucyl-homophenyl-vinyl sulfone phenyl
    J Biol Chem284, 26839-26850. PubMed  Europe PubMed DOI  I