Literature for peptidase C01.149: TgCPL peptidase (Toxoplasma-type)

(Topics flags: I Inhibitor. To select only the references relevant to a single topic, click the link above. See explanation.)

2025
1. Rimple,P.A., Olafsson,E.B., Markus,B.M., Wang,F., Augusto,L., Lourido,S. and Carruthers,V.B.<br>Metabolic adaptability and nutrient scavenging in Toxoplasma gondii: insights from ingestion pathway-deficient mutants<br>mSphere (2025) , e0101124-e0101124. PubMed  Europe PubMed DOI
2020
2. Zwicker,J.D., Smith,D., Guerra,A.J., Hitchens,J.R., Haug,N., Vander Roest,S., Lee,P., Wen,B., Sun,D., Wang,L., Keep,R., Xiang,J., Carruthers,V.B. and Larsen,S.D.<br>Discovery and optimization of triazine nitrile inhibitors of Toxoplasma gondii cathepsin L for the potential treatment of chronic toxoplasmosis in the CNS<br>ACS Chem Neurosci (2020) 11, 2450-2463. PubMed  Europe PubMed DOI  I
2018
3. Zwicker,J.D., Diaz,N.A., Guerra,A.J., Kirchhoff,P.D., Wen,B., Sun,D., Carruthers,V.B. and Larsen,S.D.<br>Optimization of dipeptidic inhibitors of cathepsin L for improved Toxoplasma gondii selectivity and CNS permeability<br>Bioorg Med Chem Lett (2018) 28, 1972-1980. PubMed  Europe PubMed DOI  I
2014
4. Coppens,I.<br>Toxoplasma, or the discovery of a heterophage<br>Trends Parasitol (2014) 30, 467-469. PubMed  Europe PubMed DOI
5. Dou,Z., McGovern,O.L., Di Cristina,M. and Carruthers,V.B.<br>Toxoplasma gondii ingests and digests host cytosolic proteins<br>MBio (2014) 5, e01188-e01114. PubMed  Europe PubMed DOI  PMC  EPMC
2013
6. Dou,Z., Coppens,I. and Carruthers,V.B.<br>Non-canonical maturation of two papain-family proteases in Toxoplasma gondii<br>J Biol Chem (2013) 288, 3523-3534. PubMed  Europe PubMed DOI
2012
7. Dou,Z. and Carruthers,V.B.<br>Toxoplasma gondii cathepsin L-like protease, TgCPL<br>[ISSN:978-0-12-407743-0] (2012) 3, 1929-1933. DOI
2011
8. Dou,Z. and Carruthers,V.B.<br>Cathepsin proteases in Toxoplasma gondii<br>Adv Exp Med Biol (2011) 712, 49-61. PubMed  Europe PubMed DOI  I
2010
9. Parussini,F., Coppens,I., Shah,P.P., Diamond,S.L. and Carruthers,V.B.<br>Cathepsin L occupies a vacuolar compartment and is a protein maturase within the endo/exocytic system of Toxoplasma gondii<br>Mol Microbiol (2010) 76, 1340-1357. PubMed  Europe PubMed DOI
2009
10. Huang,R., Que,X., Hirata,K., Brinen,L.S., Lee,J.H., Hansell,E., Engel,J., Sajid,M. and Reed,S.<br>The cathepsin L of Toxoplasma gondii (TgCPL) and its endogenous macromolecular inhibitor, toxostatin<br>Mol Biochem Parasitol (2009) 164, 86-94. PubMed  Europe PubMed DOI  PMC  EPMC
11. Larson,E.T., Parussini,F., Huynh,M.H., Giebel,J.D., Kelley,A.M., Zhang,L., Bogyo,M., Merritt,E.A. and Carruthers,V.B.<br>Toxoplasma gondii cathepsin L is the primary target of the invasion-inhibitory compound morpholinurea-leucyl-homophenyl-vinyl sulfone phenyl<br>J Biol Chem (2009) 284, 26839-26850. PubMed  Europe PubMed DOI  I