Literature for peptidase C01.129: cathepsin L3 (Fasciola sp.)

Summary Alignment Sequences Sequence features Distribution Literature Substrates

(Topics flags: P Specificity, I Inhibitor, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Chansap,S., Cheukamud,W., Suthisintong,T., Kueakhai,P. and Changklungmoa,N.
    Development of multi-epitope Cathepsin L driven short peptide vaccine against Fasciola gigantica
    Front Vet Sci12, 1547937-1547937. PubMed  Europe PubMed DOI
  2. 2023
  3. Artia,Z., Ferraro,F., Sanchez,C., Cerecetto,H., Gil,J., Pareja,L., Alonzo,M.N., Freire,T., Cabrera,M. and Corvo,I.
    In vitro and in vivo studies on a group of chalcones find promising results as potential drugs against fascioliasis
    Exp Parasitol255, 108628-108628. PubMed  Europe PubMed DOI
  4. 2021
  5. Barbour,T., Cwiklinski,K., Lalor,R., Dalton,J.P. and De Marco Verissimo,C.
    The Zoonotic Helminth Parasite Fasciola hepatica: Virulence-Associated Cathepsin B and Cathepsin L Cysteine Peptidases Secreted by Infective Newly Excysted Juveniles (NEJ)
    Animals (Basel)11, PubMed  Europe PubMed DOI
  6. Cwiklinski,K., Robinson,M.W., Donnelly,S. and Dalton,J.P.
    Complementary transcriptomic and proteomic analyses reveal the cellular and molecular processes that drive growth and development of Fasciola hepatica in the host liver
    BMC Genomics22, 46-46. PubMed  Europe PubMed DOI
  7. 2020
  8. Huang,W., Gu,M., Cheng,W., Zhao,Q.P., Ming,Z. and Dong,H.
    Characteristics and function of cathepsin L3 from Schistosoma japonicum
    Parasitol Res119, 1619-1628. PubMed  Europe PubMed DOI
  9. Pritsch,I.C., Tikhonova,I.G., Jewhurst,H.L., Drysdale,O., Cwiklinski,K., Molento,M.B., Dalton,J.P. and Verissimo,C.M.
    Regulation of the Fasciola hepatica newly excysted juvenile cathepsin L3 (FhCL3) by its propeptide: a proposed 'clamp-like' mechanism of binding and inhibition
    BMC Mol Cell Biol21, 90-90. PubMed  Europe PubMed DOI
  10. 2019
  11. Celias,D.P., Corvo,I., Silvane,L., Tort,J.F., Chiapello,L.S., Fresno,M., Arranz,A., Motran,C.C. and Cervi,L.
    Cathepsin L3 From Fasciola hepatica induces NLRP3 inflammasome alternative activation in murine dendritic cells
    Front Immunol10, 552-552. PubMed  Europe PubMed DOI
  12. 2016
  13. Ferraro,F., Merlino,A., dellOca,N., Gil,J., Tort,J.F., Gonzalez,M., Cerecetto,H., Cabrera,M. and Corvo,I.
    Identification of chalcones as Fasciola hepatica cathepsin L inhibitors using a comprehensive experimental and computational approach
    PLoS Negl Trop Dis10, e0004834-e0004834. PubMed  Europe PubMed DOI  I
  14. 2015
  15. Hernandez Alvarez,L., Naranjo Feliciano,D., Hernandez Gonzalez,J.E., de Oliveira Soares,R., Barreto Gomes,D.E. and Pascutti,P.G.
    Insights into the interactions of Fasciola hepatica cathepsin L3 with a substrate and potential novel inhibitors through in silico approaches
    PLoS Negl Trop Dis9, e0003759- PubMed  Europe PubMed DOI  I
  16. Meemon,K. and Sobhon,P.
    Juvenile-specific cathepsin proteases in Fasciola spp.: their characteristics and vaccine efficacies
    Parasitol Res114, 2807-2813. PubMed  Europe PubMed DOI
  17. 2013
  18. Corvo,I., O'Donoghue,A.J., Pastro,L., Pi-Denis,N., Eroy-Reveles,A., Roche,L., McKerrow,J.H., Dalton,J.P., Craik,C.S., Caffrey,C.R. and Tort,J.F.
    Dissecting the active site of the collagenolytic cathepsin L3 protease of the invasive stage of Fasciola hepatica
    PLoS Negl Trop Dis7, e2269-e2269. PubMed  Europe PubMed DOI  P
  19. Zawistowska-Deniziak,A., Wasyl,K., Norbury,L.J., Wesolowska,A., Bien,J., Grodzik,M., Wisniewski,M., Baska,P. and Wedrychowicz,H.
    Characterization and differential expression of cathepsin L3 alleles from Fasciola hepatica
    Mol Biochem Parasitol190, 27-37. PubMed  Europe PubMed DOI
  20. 2012
  21. Caffrey,C.R., Britton,C. and McKerrow,J.H.
    Helminth cysteine proteases
    [ISSN:978-0-12-407743-0]3, 1949-1957. DOI
  22. McVeigh,P., Maule,A.G., Dalton,J.P. and Robinson,M.W.
    Fasciola hepatica virulence-associated cysteine peptidases: a systems biology perspective
    Microbes Infect14, 301-310. PubMed  Europe PubMed DOI
  23. 2011
  24. Morphew,R.M., Wright,H.A., Lacourse,E.J., Porter,J., Barrett,J., Woods,D.J. and Brophy,P.M.
    Towards delineating functions within the Fasciola secreted cathepsin L protease family by integrating in vivo based sub-proteomics and phylogenetics
    PLoS Negl Trop Dis5, e937-e937. PubMed  Europe PubMed DOI
  25. Norbury,L.J., Beckham,S., Pike,R.N., Grams,R., Spithill,T.W., Fecondo,J.V. and Smooker,P.M.
    Adult and juvenile Fasciola cathepsin L proteases: different enzymes for different roles
    Biochimie93, 604-611. PubMed  Europe PubMed DOI  P
  26. Robinson,M.W., Corvo,I., Jones,P.M., George,A.M., Padula,M.P., To,J., Cancela,M., Rinaldi,G., Tort,J.F., Roche,L. and Dalton,J.P.
    Collagenolytic activities of the major secreted cathepsin L peptidases involved in the virulence of the helminth pathogen, Fasciola hepatica
    PLoS Negl Trop Dis5, e1012-e1012. PubMed  Europe PubMed DOI
  27. Stack,C., Dalton,J.P. and Robinson,M.W.
    The phylogeny, structure and function of trematode cysteine proteases, with particular emphasis on the Fasciola hepatica cathepsin L family
    Adv Exp Med Biol712, 116-135. PubMed  Europe PubMed DOI  V
  28. 2010
  29. Corvo,I., Cancela,M., Cappetta,M., Pi-Denis,N., Tort,J.F. and Roche,L.
    'Corrigendum to "The major cathepsin L secreted by the invasive juvenile Fasciola hepatica prefers proline in the S2 subsite and can cleave collagen" [Mol. Biochem. Parasitol. 176 (1) (2009) 41-47]' (DOI:10.1016/j.molbiopara.2009.04.005)
    Mol Biochem Parasitol176, 68-68. DOI  P
  30. 2009
  31. Corvo,I., Cancela,M., Cappetta,M., Pi-Denis,N., Tort,J.F. and Roche,L.
    The major cathepsin L secreted by the invasive juvenile Fasciola hepatica prefers proline in the S2 subsite and can cleave collagen
    Mol Biochem Parasitol167, 41-47. PubMed  Europe PubMed DOI  P
  32. 2005
  33. [YEAR:27-4-2005]Reszka,N., Cornelissen,J.B., Harmsen,M.M., Bienkowska-Szewczyk,K., de Bree,J., Boersma,W.J. and Rijsewijk,F.A.
    Fasciola hepatica procathepsin L3 protein expressed by a baculovirus recombinant can partly protect rats against fasciolosis
    Vaccine23, 2987-2993. PubMed  Europe PubMed DOI
  34. 2004
  35. Harmsen,M.M., Cornelissen,J.B., Buijs,H.E., Boersma,W.J., Jeurissen,S.H. and van Milligen,F.J.
    Identification of a novel Fasciola hepatica cathepsin L protease containing protective epitopes within the propeptide
    Int J Parasitol34, 675-682. PubMed  Europe PubMed DOI