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Literature for peptidase C01.073: peptidase 1 (mite)

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

(Topics flags: A Assay, S Structure, T Target, P Specificity, K Knockout, E Expression, V Review, I Inhibitor. To select only the references relevant to a single topic, click the link above. See explanation.)

    2024
  1. Aggarwal,P. and Senthilkumaran,S.
    Dust Mite Allergy
     PubMed  Europe PubMed
    2. 2021
  2. Ogi,K., Ramezanpour,M., Liu,S., Ferdoush Tuli,J., Bennett,C., Suzuki,M., Fujieda,S., Psaltis,A.J., Wormald,P.J. and Vreugde,S.
    Der p 1 Disrupts the Epithelial Barrier and Induces IL-6 Production in Patients With House Dust Mite Allergic Rhinitis
    Front Allergy2, 692049-692049. PubMed  Europe PubMed DOI
    3. 2020
  3. Cai,X.J., Huang,L.H., Zhu,Y.K. and Huang,Y.J.
    LncRNA OIP5AS1 aggravates house dust miteinduced inflammatory responses in human bronchial epithelial cells via the miR1433p/HMGB1 axis
    Mol Med Rep22, 4509-4518. PubMed  Europe PubMed DOI  K
  4. Lazaro-Gorines,R., Lopez-Rodriguez,J.C., Benede,S., Gonzalez,M., Mayorga,C., Vogel,L., Martinez-Del-Pozo,A., Lacadena,J. and Villalba,M.
    Der p 1-based immunotoxin as potential tool for the treatment of dust mite respiratory allergy
    Sci Rep10, 12255-12255. PubMed  Europe PubMed DOI
  5. Zhang,R., Trower,J. and Wu,T.
    Degradation of bacterial permeability family member A1 (BPIFA1) by house dust mite (HDM) cysteine protease cabrogates immune modulator function
    Int J Biol Macromol164, 4031- PubMed  Europe PubMed DOI
    6. 2019
  6. Zhang,J. and Robinson,C.
    Novel method for the purification of house dust mite allergen Der p 1 and its use in structure-based chemical design of novel inhibitors
    Methods Mol Biol2020, 185-205. PubMed  Europe PubMed DOI  I
    7. 2018
  7. Chevigne,A. and Jacquet,A.
    Emerging roles of the protease allergen Der p 1 in house dust mite-induced airway inflammation
    J Allergy Clin Immunol142, 398-400. PubMed  Europe PubMed DOI  V
  8. Cui,Y., Yu,L., Teng,F., Wang,N., Zhou,Y., Zhang,C. and Yang,L.
    Expression of recombinant allergen, Der f 1, Der f 2 and Der f 4 using baculovirus-insect cell systems
    Arch Med Sci14, 1348-1354. PubMed  Europe PubMed DOI  E
  9. Zhang,J., Chen,J., Zuo,J., Newton,G.K., Stewart,M.R., Perrior,T.R., Garrod,D.R. and Robinson,C.
    Allergen delivery inhibitors: characterisation of potent and selective inhibitors of Der p 1 and their attenuation of airway responses to house dust mite allergens
    Int J Mol Sci19, PubMed  Europe PubMed DOI  I
    10. 2017
  10. Chevigne,A., Campizi,V., Szpakowska,M., Bourry,D., Dumez,M.E., Martins,J.C., Matagne,A., Galleni,M. and Jacquet,A.
    The Lys-Asp-Tyr triad within the mite allergen Der p 1 propeptide is a critical structural element for the pH-dependent initiation of the protease maturation
    Int J Mol Sci18, PubMed  Europe PubMed DOI
  11. Glesner,J., Vailes,L.D., Schlachter,C., Mank,N., Minor,W., Osinski,T., Chruszcz,M., Chapman,M.D. and Pomes,A.
    Antigenic determinants of Der p 1: specificity and cross-reactivity associated with IgE antibody recognition
    J Immunol198, 1334-1344. PubMed  Europe PubMed DOI
  12. Jacquet,A., Campisi,V., Szpakowska,M., Dumez,M.E., Galleni,M. and Chevigne,A.
    Profiling the extended cleavage specificity of the house dust mite protease allergens Der p 1, Der p 3 and Der p 6 for the prediction of new cell surface protein substrates
    Int J Mol Sci18, PubMed  Europe PubMed DOI  P
  13. Oida,K., Einhorn,L., Herrmann,I., Panakova,L., Resch,Y., Vrtala,S., Hofstetter,G., Tanaka,A., Matsuda,H. and Jensen-Jarolim,E.
    Innate function of house dust mite allergens: robust enzymatic degradation of extracellular matrix at elevated pH
    World Allergy Organ J10, 23-23. PubMed  Europe PubMed DOI
  14. Randall,T.A., London,R.E., Fitzgerald,M.C. and Mueller,G.A.
    Proteases of Dermatophagoides pteronyssinus
    Int J Mol Sci18, PubMed  Europe PubMed DOI
  15. Reddy,V.B. and Lerner,E.A.
    Activation of mas-related G-protein-coupled receptors by the house dust mite cysteine protease Der p1 provides a new mechanism linking allergy and inflammation
    J Biol Chem292, 17399-17406. PubMed  Europe PubMed DOI
    16. 2015
  16. Ling,C., Zhang,J., Chen,H., Zou,Z., Lai,H., Zhang,J., Lin,D. and Tao,A.
    Expression and refolding of mite allergen pro-Der f1 from inclusion bodies in Escherichia coli
    Protein Expr Purif109, 93-98. PubMed  Europe PubMed DOI  E
  17. Osinski,T., Pomes,A., Majorek,K.A., Glesner,J., Offermann,L.R., Vailes,L.D., Chapman,M.D., Minor,W. and Chruszcz,M.
    Structural analysis of Der p 1-antibody complexes and comparison with complexes of proteins or peptides with monoclonal antibodies
    J Immunol195, 307-316. PubMed  Europe PubMed DOI  S
  18. Yi,M.H., Kim,H.P., Jeong,K.Y., Kim,C.R., Kim,T.Y. and Yong,T.S.
    House dust mite allergen Der f 1 induces IL-8 in human basophilic cells via ROS-ERK and p38 signal pathways
    Cytokine75, 356-364. PubMed  Europe PubMed DOI
    19. 2014
  19. Dumez,M.E., Herman,J., Campizi,V., Galleni,M., Jacquet,A. and Chevigne,A.
    Orchestration of an uncommon maturation cascade of the house dust mite protease allergen quartet
    Front Immunol5, 138-138. PubMed  Europe PubMed DOI
  20. Herman,J., Thelen,N., Smargiasso,N., Mailleux,A.C., Luxen,A., Cloes,M., de Pauw,E., Chevigne,A., Galleni,M. and Dumez,M.E.
    Der p 1 is the primary activator of Der p 3, Der p 6 and Der p 9 the proteolytic allergens produced by the house dust mite Dermatophagoides pteronyssinus
    Biochim Biophys Acta1840, 1117-1124. PubMed  Europe PubMed DOI
  21. Jiang,Y.X., Yin,K., Jin,W.J., Wu,L.Y. and Li,C.P.
    [Experimental study on the Der f 1 mRNA molecules derived from Dermatophagoides farinae for specific immunotherapy on murine model of asthma]
    Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi32, 268-273. PubMed  Europe PubMed
  22. Liu,Z., Jiang,Y. and Li,C.
    Design of a ProDer f 1 vaccine delivered by the MHC class II pathway of antigen presentation and analysis of the effectiveness for specific immunotherapy
    Int J Clin Exp Pathol7, 4636-4644. PubMed  Europe PubMed
  23. Newton,G.K., Perrior,T.R., Jenkins,K., Major,M.R., Key,R.E., Stewart,M.R., Firth-Clark,S., Lloyd,S.M., Zhang,J., Francis-Newton,N.J., Richardson,J.P., Chen,J., Lai,P., Garrod,D.R. and Robinson,C.
    The discovery of potent, selective, and reversible inhibitors of the house dust mite peptidase allergen Der p 1: an innovative approach to the treatment of allergic asthma
    J Med Chem57, 9447-9462. PubMed  Europe PubMed DOI  T  I
  24. Shafique,R.H., Klimov,P.B., Inam,M., Chaudhary,F.R. and OConnor,B.M.
    Group 1 allergen genes in two species of house dust mites, Dermatophagoides farinae and D. pteronyssinus (Acari: Pyroglyphidae): direct sequencing, characterization and polymorphism
    PLoS ONE9, e114636-e114636. PubMed  Europe PubMed DOI
    25. 2013
  25. Kamijo,S., Takeda,H., Tokura,T., Suzuki,M., Inui,K., Hara,M., Matsuda,H., Matsuda,A., Oboki,K., Ohno,T., Saito,H., Nakae,S., Sudo,K., Suto,H., Ichikawa,S., Ogawa,H., Okumura,K. and Takai,T.
    IL-33-Mediated innate response and adaptive immune cells contribute to maximum responses of protease allergen-induced allergic airway inflammation
    J Immunol190, 4489-4499. PubMed  Europe PubMed DOI
  26. Liao,Y.W., Wu,X.M., Jia,J., Wu,X.L., Tao,H. and Wang,H.Y.
    Proteolytic antigens interfere with endosome/lysosome fusion in epithelial cells
    Biochem Cell Biol91, 449-454. PubMed  Europe PubMed DOI
  27. Serrano-Luna,J., Pina-Vazquez,C., Reyes-Lopez,M., Ortiz-Estrada,G. and de la Garza,M.
    Proteases from Entamoeba spp. and pathogenic free-living amoebae as virulence factors
    J Trop Med2013, 890603-890603. PubMed  Europe PubMed DOI  V
  28. Warmbold,C., Uliczka,K., Rus,F., Suck,R., Petersen,A., Silverman,N., Ulmer,A.J., Heine,H. and Roeder,T.
    Dermatophagoides pteronyssinus major allergen 1 activates the innate immune response of the fruit fly Drosophila melanogaster
    J Immunol190, 366-371. PubMed  Europe PubMed DOI
    29. 2012
  29. Marconi,G., Albertini,E., Mari,A., Palazzo,P., Porceddu,A., Raggi,L., Bolis,L., Lancioni,H., Palomba,A., Lucentini,L., Lanfaloni,L., Marcucci,F., Falcinelli,M. and Panara,F.
    In planta expression of a mature Der p 1 allergen isolated from an Italian strain of Dermatophagoides pteronyssinus
    Transgenic Res21, 523-535. PubMed  Europe PubMed DOI  E
  30. Prester,L., Kovacic,J. and Macan,J.
    Comparison of buffers for extraction of mite allergen der p 1 from dust
    Arh Hig Rada Toksikol63, 293-300. PubMed  Europe PubMed DOI
  31. Takai,T.
    Mite endopeptidase 1
    [ISSN:978-0-12-407743-0]3, 1957-1963. DOI
    32. 2011
  32. Bessot,J.C. and Pauli,G.
    Mite allergens: an overview
    Eur Ann Allergy Clin Immunol43, 141-156. PubMed  Europe PubMed
  33. Dai,Y.C., Chuang,W.J., Chua,K.Y., Shieh,C.C. and Wang,J.Y.
    Epitope mapping and structural analysis of the anti-Der p 1 monoclonal antibody: insight into therapeutic potential
    J Mol Med (Berl)89, 701-712. PubMed  Europe PubMed DOI
  34. Fukunaga,M., Gon,Y., Nunomura,S., Inoue,T., Yoshioka,M., Hashimoto,S. and Ra,C.
    Protease-mediated house dust mite allergen-induced reactive oxygen species production by neutrophils
    Int Arch Allergy Immunol155 Suppl 1, 104-109. PubMed  Europe PubMed DOI
  35. Jacquet,A.
    Interactions of airway epithelium with protease allergens in the allergic response
    Clin Exp Allergy41, 305-311. PubMed  Europe PubMed DOI
    36. 2010
  36. Chevigne,A., Dumez,M.E., Dumoulin,M., Matagne,A., Jacquet,A. and Galleni,M.
    Comparative study of mature and zymogen mite cysteine protease stability and pH unfolding
    Biochim Biophys Acta1800, 937-945. PubMed  Europe PubMed DOI
  37. Kondoh,M., Fukada,K., Shimada,T., Kitamura,Y., Yasueda,H. and Enomoto,T.
    [Highly sensitive enzyme-linked immunosorbent assay for the quantification of allergens from Dermatophagoides, DER p 1 and DER f 1]
    Arerugi59, 109-116. PubMed  Europe PubMed
  38. Pulsawat,P., Piboonpocanun,S., Sirivichayakul,S., Buranapraditkun,S., Jacquet,A., Shimada,M., Okuda,K. and Ruxrungtham,K.
    Production and immunogenicity of hypoallergenic codon-optimized DNA vaccine encoding mature Der p 1 allergen
    J Investig Allergol Clin Immunol20, 582-590. PubMed  Europe PubMed
    39. 2009
  39. Burtin,D., Chabre,H., Olagnier,B., Didierlaurent,A., Couret,M.N., Comeau,D., Wambre,E., Laparra,H., Van Overtvelt,L., Montandon,F., Batard,T., Jonval,V., Lorphelin,A., Merle,C., Berrouet,C., Parry,L., Gomord,V., Van Ree,R. and Moingeon,P.
    Production of native and modified recombinant Der p 1 molecules in tobacco plants
    Clin Exp Allergy39, 760-770. PubMed  Europe PubMed DOI  E
  40. Chruszcz,M., Chapman,M.D., Vailes,L.D., Stura,E.A., Saint-Remy,J.M., Minor,W. and Pomes,A.
    Crystal structures of mite allergens Der f 1 and Der p 1 reveal differences in surface-exposed residues that may influence antibody binding
    J Mol Biol386, 520-530. PubMed  Europe PubMed DOI  S
  41. Nakamura,Y., Miyata,M., Shimokawa,N., Ohnuma,Y., Katoh,R., Ogawa,H., Okumura,K. and Nakao,A.
    House dust mite allergen Der f 1 can induce the activation of latent TGF-beta via its protease activity
    FEBS Lett583, 2088-2092. PubMed  Europe PubMed DOI
  42. Takai,T., Kato,T., Hatanaka,H., Inui,K., Nakazawa,T., Ichikawa,S., Mitsuishi,K., Ogawa,H. and Okumura,K.
    Modulation of allergenicity of major house dust mite allergens Der f 1 and Der p 1 by interaction with an endogenous ligand
    J Immunol183, 7958-7965. PubMed  Europe PubMed DOI
  43. Zhang,J., Saint-Remy,J.M., Garrod,D.R. and Robinson,C.
    Comparative enzymology of native and recombinant house dust mite allergen Der p 1
    Allergy64, 469-477. PubMed  Europe PubMed DOI  I
    44. 2008
  44. Cui,Y., Zhou,P., Peng,J., Peng,M., Zhou,Y., Lin,Y. and Liu,L.
    Cloning, sequence analysis, and expression of cDNA coding for the major house dust mite allergen, Der f 1, in Escherichia coli
    Braz J Med Biol Res41, 380-388. PubMed  Europe PubMed  E
  45. Dumez,M.E., Teller,N., Mercier,F., Tanaka,T., Vandenberghe,I., Vandenbranden,M., Devreese,B., Luxen,A., Frere,J.M., Matagne,A., Jacquet,A., Galleni,M. and Chevigne,A.
    Activation mechanism of recombinant Der p 3 allergen zymogen: contribution of cysteine protease Der p 1 and effect of propeptide glycosylation
    J Biol Chem283, 30606-30617. PubMed  Europe PubMed DOI
  46. Ogawa,T., Takai,T., Kato,T., Kikuchi,Y., Niyonsaba,F., Ikeda,S., Okumura,K. and Ogawa,H.
    Upregulation of the release of granulocyte-macrophage colony-stimulating factor from keratinocytes stimulated with cysteine protease activity of recombinant major mite allergens, Der f 1 and Der p 1
    Int Arch Allergy Immunol146, 27-35. PubMed  Europe PubMed DOI
    47. 2007
  47. Chapman,M.D., Wunschmann,S. and Pomes,A.
    Proteases as th2 adjuvants
    Curr Allergy Asthma Rep7, 363-367. PubMed  Europe PubMed DOI
  48. Chevigne,A., Barumandzadeh,R., Groslambert,S., Cloes,B., Dehareng,D., Filee,P., Marx,J.C., Frere,J.M., Matagne,A., Jacquet,A. and Galleni,M.
    Relationship between propeptide pH unfolding and inhibitory ability during proDer p 1 activation mechanism
    J Mol Biol374, 170-185. PubMed  Europe PubMed DOI
  49. Deb,R., Shakib,F., Reid,K. and Clark,H.
    Major house dust mite allergens Dermatophagoides pteronyssinus 1 and Dermatophagoides farinae 1 degrade and inactivate lung surfactant proteins A and D
    J Biol Chem282, 36808-36819. PubMed  Europe PubMed DOI
  50. Furmonaviciene,R., Ghaemmaghami,A.M., Boyd,S.E., Jones,N.S., Bailey,K., Willis,A.C., Sewell,H.F., Mitchell,D.A. and Shakib,F.
    The protease allergen Der p 1 cleaves cell surface DC-SIGN and DC-SIGNR: experimental analysis of in silico substrate identification and implications in allergic responses
    Clin Exp Allergy37, 231-242. PubMed  Europe PubMed DOI  P
  51. Meng,J.F., McFall,C. and Rosenwasser,L.J.
    Polymorphism R62W results in resistance of CD23 to enzymatic cleavage in cultured cells
    Genes Immun8, 215-223. PubMed  Europe PubMed DOI
  52. Nisbet,A.J., MacKellar,A., McLean,K., Brennan,G.P. and Huntley,J.F.
    Eukaryotic expression of recombinant Pso o 1, an allergen from Psoroptes ovis, and its localization in the mite
    Parasitology134, 83-89. PubMed  Europe PubMed DOI  E
  53. Zhang,J., Hamilton,J.M., Garrod,D.R. and Robinson,C.
    Interactions between mature Der p 1 and its free prodomain indicate membership of a new family of C1 peptidases
    Allergy62, 1302-1309. PubMed  Europe PubMed DOI
    54. 2006
  54. [YEAR:17-11-2006]Adam,E., Hansen,K.K., Astudillo,O.F., Coulon,L., Bex,F., Duhant,X., Jaumotte,E., Hollenberg,M.D. and Jacquet,A.
    The house dust mite allergen Der p 1, unlike Der p 3, stimulates the expression of interleukin-8 in human airway epithelial cells via a proteinase-activated receptor-2-independent mechanism
    J Biol Chem281, 6910-6923. PubMed  Europe PubMed DOI
  55. de Halleux,S., Stura,E., VanderElst,L., Carlier,V., Jacquemin,M. and Saint-Remy,J.M.
    Three-dimensional structure and IgE-binding properties of mature fully active Der p 1, a clinically relevant major allergen
    J Allergy Clin Immunol117, 571-576. PubMed  Europe PubMed DOI  S
  56. Kauffman,H.F., Tamm,M., Timmerman,J.A. and Borger,P.
    House dust mite major allergens Der p 1 and Der p 5 activate human airway-derived epithelial cells by protease-dependent and protease-independent mechanisms
    Clin Mol Allergy4, 5-5. PubMed  Europe PubMed DOI
  57. [YEAR:1-8-2006]Kikuchi,Y., Takai,T., Kuhara,T., Ota,M., Kato,T., Hatanaka,H., Ichikawa,S., Tokura,T., Akiba,H., Mitsuishi,K., Ikeda,S., Okumura,K. and Ogawa,H.
    Crucial commitment of proteolytic activity of a purified recombinant major house dust mite allergen Der p1 to sensitization toward IgE and IgG responses
    J Immunol177, 1609-1617. PubMed  Europe PubMed
  58. [YEAR:28-9-2006]Nakamura,T., Hirasawa,Y., Takai,T., Mitsuishi,K., Okuda,M., Kato,T., Okumura,K., Ikeda,S. and Ogawa,H.
    Reduction of skin barrier function by proteolytic activity of a recombinant house dust mite major allergen Der f 1
    J Invest Dermatol126, 2719-2723. PubMed  Europe PubMed DOI
  59. [YEAR:26-1-2006]Takai,T., Mizuuchi,E., Kikuchi,Y., Nagamune,T., Okumura,K. and Ogawa,H.
    Glycosylation of recombinant proforms of major house dust mite allergens Der p 1 and Der f 1 decelerates the speed of maturation
    Int Arch Allergy Immunol139, 181-187. PubMed  Europe PubMed DOI
    60. 2005
  60. Grunstein,M.M., Veler,H., Shan,X., Larson,J., Grunstein,J.S. and Chuang,S.
    Proasthmatic effects and mechanisms of action of the dust mite allergen, Der p 1, in airway smooth muscle
    J Allergy Clin Immunol116, 94-101. PubMed  Europe PubMed DOI
  61. Kato,T., Takai,T., Mitsuishi,K., Okumura,K. and Ogawa,H.
    Cystatin A inhibits IL-8 production by keratinocytes stimulated with Der p 1 and Der f 1: biochemical skin barrier against mite cysteine proteases
    J Allergy Clin Immunol116, 169-176. PubMed  Europe PubMed DOI
  62. [YEAR:15-9-2005]Meno,K., Thorsted,P.B., Ipsen,H., Kristensen,O., Larsen,J.N., Spangfort,M.D., Gajhede,M. and Lund,K.
    The crystal structure of recombinant proDer p 1, a major house dust mite proteolytic allergen
    J Immunol175, 3835-3845. PubMed  Europe PubMed  S
  63. Pichavant,M., Charbonnier,A.S., Taront,S., Brichet,A., Wallaert,B., Pestel,J., Tonnel,A.B. and Gosset,P.
    Asthmatic bronchial epithelium activated by the proteolytic allergen Der p 1 increases selective dendritic cell recruitment
    J Allergy Clin Immunol115, 771-778. PubMed  Europe PubMed DOI
  64. [YEAR:25-3-2005]Takai,T., Kato,T., Sakata,Y., Yasueda,H., Izuhara,K., Okumura,K. and Ogawa,H.
    Recombinant Der p 1 and Der f 1 exhibit cysteine protease activity but no serine protease activity
    Biochem Biophys Res Commun328, 944-952. PubMed  Europe PubMed DOI
  65. Takai,T., Kato,T., Yasueda,H., Okumura,K. and Ogawa,H.
    Analysis of the structure and allergenicity of recombinant pro- and mature Der p 1 and Der f 1: major conformational IgE epitopes blocked by prodomains
    J Allergy Clin Immunol115, 555-563. PubMed  Europe PubMed DOI  E
  66. [YEAR:9-6-2005]Takai,T., Kato,T., Ota,M., Yasueda,H., Kuhara,T., Okumura,K. and Ogawa,H.
    Recombinant Der p 1 and Der f 1 with in vitro enzymatic activity to cleave human CD23, CD25 and alpha1-antitrypsin, and in vivo IgE-eliciting activity in mice
    Int Arch Allergy Immunol137, 194-200. PubMed  Europe PubMed DOI  E
    67. 2004
  67. Harris,J., Mason,D.E., Li,J., Burdick,K.W., Backes,B.J., Chen,T., Shipway,A., Van Heeke,G., Gough,L., Ghaemmaghami,A., Shakib,F., Debaene,F. and Winssinger,N.
    Activity profile of dust mite allergen extract using substrate libraries and functional proteomic microarrays
    Chem Biol11, 1361-1372. PubMed  Europe PubMed DOI
  68. Meighan,P. and Pirzad,R.
    Mite endopeptidase 1
    [ISSN:0-12-079610-4]2, 1187-1189.  V
  69. [YEAR:20-11-2004]Sakata,Y., Arima,K., Takai,T., Sakurai,W., Masumoto,K., Yuyama,N., Suminami,Y., Kishi,F., Yamashita,T., Kato,T., Ogawa,H., Fujimoto,K., Matsuo,Y., Sugita,Y. and Izuhara,K.
    The squamous cell carcinoma antigen 2 inhibits the cysteine proteinase activity of a major mite allergen, Der p 1
    J Biol Chem279, 5081-5087. PubMed  Europe PubMed DOI
    70. 2003
  70. Cheong,N., Soon,S.C., Ramos,J.D., Kuo,I.C., Kolatkar,P.R., Lee,B.W., Chua,K.Y. and Kolortkar,P.R.
    Lack of human IgE cross-reactivity between mite allergens Blo t 1 and Der p 1
    Allergy58, 912-920. PubMed  Europe PubMed DOI
  71. Gough,L., Campbell,E., Bayley,D., Van Heeke,G. and Shakib,F.
    Proteolytic activity of the house dust mite allergen Der p 1 enhances allergenicity in a mouse inhalation model
    Clin Exp Allergy33, 1159-1163. PubMed  Europe PubMed DOI
    72. 2002
  72. [YEAR:15-10-2002]Asokananthan,N., Graham,P.T., Stewart,D.J., Bakker,A.J., Eidne,K.A., Thompson,P.J. and Stewart,G.A.
    House dust mite allergens induce proinflammatory cytokines from respiratory epithelial cells: The cysteine protease allergen, Der p 1, activates protease-activated receptor (PAR)-2 and inactivates PAR-1
    J Immunol169, 4572-4578. PubMed  Europe PubMed
  73. Ghaemmaghami,A.M. and Shakib,F.
    Human T cells that have been conditioned by the proteolytic activity of the major dust mite allergen Der p 1 trigger enhanced immunoglobulin E synthesis by B cells
    Clin Exp Allergy32, 728-732. PubMed  Europe PubMed DOI
  74. Ghaemmaghami,A.M., Gough,L., Sewell,H.F. and Shakib,F.
    The proteolytic activity of the major dust mite allergen Der p 1 conditions dendritic cells to produce less interleukin-12: allergen-induced Th2 bias determined at the dendritic cell level
    Clin Exp Allergy32, 1468-1475. PubMed  Europe PubMed DOI
  75. Jacquet,A., Magi,M., Petry,H. and Bollen,A.
    High-level expression of recombinant house dust mite allergen Der p 1 in Pichia pastoris
    Clin Exp Allergy32, 1048-1053. PubMed  Europe PubMed DOI  E
  76. Lee,A.J., Machell,J., Van Den Broek,A.H., Nisbet,A.J., Miller,H.R., Isaac,R.E. and Huntley,J.F.
    Identification of an antigen from the sheep scab mite, Psoroptes ovis, homologous with house dust mite group I allergens
    Parasite Immunol24, 413-422. PubMed  Europe PubMed DOI
  77. [YEAR:6-11-2002]Takai,T., Mineki,R., Nakazawa,T., Takaoka,M., Yasueda,H., Murayama,K., Okumura,K. and Ogawa,H.
    Maturation of the activities of recombinant mite allergens Der p 1 and Der f 1, and its implication in the blockade of proteolytic activity
    FEBS Lett531, 265-272. PubMed  Europe PubMed DOI
  78. van Oort,E., de Heer,P.G., van Leeuwen,W.A., Derksen,N.I., Muller,M., Huveneers,S., Aalberse,R.C. and Van Ree,R.
    Maturation of Pichia pastoris-derived recombinant pro-Der p 1 induced by deglycosylation and by the natural cysteine protease Der p 1 from house dust mite
    Eur J Biochem269, 671-679. PubMed  Europe PubMed DOI
    79. 2001
  79. Ghaemmaghami,A.M., Robins,A., Gough,L., Sewell,H.F. and Shakib,F.
    Human T cell subset commitment determined by the intrinsic property of antigen: the proteolytic activity of the major mite allergen Der p 1 conditions T cells to produce more IL-4 and less IFN-gamma
    Eur J Immunol31, 1211-1216. PubMed  Europe PubMed DOI
  80. Gough,L., Sewell,H.F. and Shakib,F.
    The proteolytic activity of the major dust mite allergen Der p 1 enhances the IgE antibody response to a bystander antigen
    Clin Exp Allergy31, 1594-1598. PubMed  Europe PubMed DOI
  81. Takahashi,K., Takai,T., Yasuhara,T., Yokota,T. and Okumura,Y.
    Effects of site-directed mutagenesis in the cysteine residues and the N-glycosylation motif in recombinant Der f 1 on secretion and protease activity
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