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Literature for peptidase C01.064: RD21 peptidase

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Literature Substrates

(Topics flags: S Structure, P Specificity, I Inhibitor, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Li,C., Li,S., Feng,L., Cheng,J., Xie,J., Lin,Y., Fu,Y., Tsuda,K., Jiang,D. and Chen,T.
    Arabidopsis OTU2 deubiquitinates cysteine protease RD21A to enhance clubroot resistance
    Plant J (2025) 122, e70148-e70148. PubMed  Europe PubMed DOI  PMC  EPMC
  2. Zhong,K., Xu,G., Shi,J., Liu,P., Tu,A., Wu,M., Liu,J., Chen,J. and Yang,J.
    NbPIRIN promotes the protease activity of papain-like cysteine protease NbRD21 to inhibit Chinese wheat mosaic virus infection
    PLoS Pathog (2025) 21, e1013037-e1013037. PubMed  Europe PubMed DOI  PMC  EPMC
    3. 2020
  3. Liu,Y., Wang,K., Cheng,Q., Kong,D., Zhang,X., Wang,Z., Wang,Q., Qi,X., Yan,J., Chu,J., Ling,H., Li,Q., Miao,J. and Zhao,B.
    Cysteine protease RD21A regulated by E3 ligase SINAT4 is required for drought-induced resistance to Pseudomonas syringae in Arabidopsis
    J Exp Bot (2020) PubMed  Europe PubMed DOI
    4. 2019
  4. Jutras,P.V., Grosse-Holz,F., Kaschani,F., Kaiser,M., Michaud,D. and van der Hoorn,R.A.L.
    Activity-based proteomics reveals nine target proteases for the recombinant protein-stabilizing inhibitor SlCYS8 in Nicotiana benthamiana
    Plant Biotechnol J (2019) 17, 1670-1678. PubMed  Europe PubMed DOI
  5. Ormancey,M., Thuleau,P., van der Hoorn,R.A.L., Grat,S., Testard,A., Kamal,K.Y., Boudsocq,M., Cotelle,V. and Mazars,C.
    Sphingolipid-induced cell death in Arabidopsis is negatively regulated by the papain-like cysteine protease RD21
    Plant Sci (2019) 280, 12-17. PubMed  Europe PubMed DOI
  6. Pogorelko,G.V., Juvale,P.S., Rutter,W.B., Hutten,M., Maier,T.R., Hewezi,T., Paulus,J., Van Der Hoorn,R.A., Grundler,F.M., Siddique,S., Lionetti,V., Zabotina,O.A. and Baum,T.J.
    Re-targeting of a plant defense protease by a cyst nematode effector
    Plant J (2019) 98, 1000-1014. PubMed  Europe PubMed DOI
    7. 2018
  7. Rustgi,S., Boex-Fontvieille,E., Reinbothe,C., Von Wettstein,D. and Reinbothe,S.
    The complex world of plant protease inhibitors: insights into a Kunitz-type cysteine protease inhibitor of Arabidopsis thaliana
    Commun Integr Biol (2018) 11, e1368599-e1368599. PubMed  Europe PubMed DOI  PMC  EPMC
    8. 2017
  8. Rustgi,S., Boex-Fontvieille,E., Reinbothe,C., Von Wettstein,D. and Reinbothe,S.
    Serpin1 and WSCP differentially regulate the activity of the cysteine protease RD21 during plant development in Arabidopsis thaliana
    Proc Natl Acad Sci U S A (2017) 114, 2212-2217. PubMed  Europe PubMed DOI
    9. 2016
  9. Boex-Fontvieille,E., Rustgi,S., Von Wettstein,D., Pollmann,S., Reinbothe,S. and Reinbothe,C.
    An ethylene-protected Achilles' heel of etiolated seedlings for arthropod deterrence
    Front Plant Sci (2016) 7, 1246-1246. PubMed  Europe PubMed DOI  PMC  EPMC
  10. Misas-Villamil,J.C., Van Der Hoorn,R.A. and Doehlemann,G.
    Papain-like cysteine proteases as hubs in plant immunity
    New Phytol (2016) 212, 902-907. PubMed  Europe PubMed DOI  V
    11. 2015
  11. Boex-Fontvieille,E., Rustgi,S., Von Wettstein,D., Reinbothe,S. and Reinbothe,C.
    Water-soluble chlorophyll protein is involved in herbivore resistance activation during greening of Arabidopsis thaliana
    Proc Natl Acad Sci U S A (2015) 112, 7303-7308. PubMed  Europe PubMed DOI
  12. Boex-Fontvieille,E., Rustgi,S., Reinbothe,S. and Reinbothe,C.
    A Kunitz-type protease inhibitor regulates programmed cell death during flower development in Arabidopsis thaliana
    J Exp Bot (2015) 66, 6119-6135. PubMed  Europe PubMed DOI
    13. 2013
  13. Lampl,N., Alkan,N., Davydov,O. and Fluhr,R.
    Set-point control of RD21 protease activity by AtSerpin1 controls cell death in Arabidopsis
    Plant J (2013) 74, 498-510. PubMed  Europe PubMed DOI
    14. 2012
  14. Gu,C., Shabab,M., Strasser,R., Wolters,P.J., Shindo,T., Niemer,M., Kaschani,F., Mach,L. and Van Der Hoorn,R.A.
    Post-translational regulation and trafficking of the granulin-containing protease RD21 of Arabidopsis thaliana
    PLoS ONE (2012) 7, e32422-e32422. PubMed  Europe PubMed DOI  PMC  EPMC
  15. Shindo,T., Misas-Villamil,J.C., Horger,A.C., Song,J. and Van Der Hoorn,R.A.
    A role in immunity for Arabidopsis cysteine protease RD21, the ortholog of the tomato immune protease C14
    PLoS ONE (2012) 7, e29317-e29317. PubMed  Europe PubMed DOI  PMC  EPMC
  16. van der Hoorn,R.A.L.
    RD21 peptidase
    [ISSN:978-0-12-407743-0] (2012) 3, 1892-1896. DOI
    17. 2010
  17. Lampl,N., Budai-Hadrian,O., Davydov,O., Joss,T.V., Harrop,S.J., Curmi,P.M., Roberts,T.H. and Fluhr,R.
    Arabidopsis AtSerpin1, crystal structure and in vivo interaction with its target protease RESPONSIVE TO DESICCATION-21 (RD21)
    J Biol Chem (2010) 285, 13550-13560. PubMed  Europe PubMed DOI  S  I
    18. 2008
  18. Carrico,I.
    Unexpected N-terminal editing: a cysteine protease that cuts and pastes
    Nat Chem Biol (2008) 4, 525-526. PubMed  Europe PubMed DOI
  19. Kikuchi,Y., Saika,H., Yuasa,K., Nagahama,M. and Tsuji,A.
    Isolation and biochemical characterization of two forms of RD21 from cotyledons of daikon radish (Raphanus sativus)
    J Biochem (2008) 144, 789-798. PubMed  Europe PubMed DOI  P
  20. Peng,S.Q., Zhu,J.H., Li,H.L. and Tian,W.M.
    Cloning and characterization of a novel cysteine protease gene (HbCP1) from Hevea brasiliensis
    J Biosci (2008) 33, 681-690. PubMed  Europe PubMed DOI
  21. Wang,Z., Gu,C., Colby,T., Shindo,T., Balamurugan,R., Waldmann,H., Kaiser,M. and Van Der Hoorn,R.A.
    beta-Lactone probes identify a papain-like peptide ligase in Arabidopsis thaliana
    Nat Chem Biol (2008) 4, 557-563. PubMed  Europe PubMed DOI
    22. 2006
  22. Halls,C.E., Rogers,S.W., Oufattole,M., Ostergard,O., Svensson,B. and Rogers,J.C.
    A Kunitz-type cysteine protease inhibitor from cauliflower and Arabidopsis
    Plant Sci (2006) 170, 1102-1110.
    23. 2005
  23. Halls,C.E., Rogers,S.W. and Rogers,J.C.
    Purification of a proaleurain maturation protease
    Plant Sci (2005) 168, 1267-1279.
    24. 2001
  24. Cervantes,E., De Diego,J.G., Gomez,M.D., Las Rivas,J., Igual,J.M., Velazquez,E., Grappin,P., Cercos,M. and Carbonell,J.
    Expression of cysteine proteinase mRNA in chickpea (Cicer arietinum L.) is localized to provascular cells in the developing root
    J Plant Physiol (2001) 158, 1463-1469.
  25. Hayashi,Y., Yamada,K., Shimada,T., Matsushima,R., Nishizawa,N.K., Nishimura,M. and Hara-Nishimura,I.
    A proteinase-storing body that prepares for cell death or stresses in the epidermal cells of Arabidopsis
    Plant Cell Physiol (2001) 42, 894-899. PubMed  Europe PubMed
  26. Yamada,K., Matsushima,R., Nishimura,M. and Hara-Nishimura,I.
    A slow maturation of a cysteine protease with a granulin domain in the vacuoles of senescing Arabidopsis leaves
    Plant Physiol (2001) 127, 1626-1634. PubMed  Europe PubMed DOI  PMC  EPMC
    27. 1993
  27. Koizumi,M., Yamaguchi-Shinozaki,K., Tsuji,H. and Shinozaki,K.
    Structure and expression of two genes that encode distinct drought-inducible cysteine proteinases in Arabidopsis thaliana
    Gene (1993) 129, 175-182. PubMed  Europe PubMed DOI

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