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Literature for peptidase A26.001: omptin

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

(Topics flags: S Structure, I Inhibitor, P Specificity, E Expression, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2024
  1. Liu,J., Jiang,L., Wang,H., Wu,J., Gao,Q., Huan,C. and Gao,S.
    Protamine cleavage specificity of the avian pathogen Escherichia coli OmpT reveals two substrate-binding sites related to virulence
    Front Vet Sci11, 1410113-1410113. PubMed  Europe PubMed DOI
    2. 2023
  2. Chen,C., Song,M., Li,K., Yan,S., Chen,M. and Geng,J.
    E. coli outer membrane protein T (OmpT) nanopore for peptide sensing
    Biochem Biophys Res Commun677, 132-140. PubMed  Europe PubMed DOI
    3. 2022
  3. Park,S., Park,K., Cho,H., Kwon,J., Kim,K.S. and Yang,H.
    Wash-Free Amperometric Escherichia coli Detection via Rapid and Specific Proteolytic Cleavage by Its Outer Membrane OmpT
    Anal Chem94, 4756-4762. PubMed  Europe PubMed DOI
    4. 2020
  4. Holt,B.A. and Kwong,G.A.
    Protease circuits for processing biological information
    Nat Commun11, 5021-5021. PubMed  Europe PubMed DOI
  5. Hu,Y., Zhang,L., Chen,J., Yao,J., Jin,H. and Yang,P.
    Outer membrane protease OmpT-based strategy for simplified analysis of histone post-translational modifications by mass spectrometry
    Anal Chem92, 732-739. PubMed  Europe PubMed DOI  P
  6. Sinsinbar,G., Gudlur,S., Wood,S.E., Ammanath,G., Yildiz,H.U., Alagappan,P., Mrksich,M. and Liedberg,B.
    Outer Membrane Protease (OmpT)-based E. coli Sensing with Anionic Polythiophene and Unlabeled Peptide Substrate
    Angew Chem Int Ed Engl59, 18068-18077. PubMed  Europe PubMed DOI
  7. Torres,A.N., Chamorro-Veloso,N., Costa,P., Cadiz,L., Del Canto,F., Venegas,S.A., Lopez Nitsche,M., Coloma-Rivero,R.F., Montero,D.A. and Vidal,R.M.
    Deciphering Additional Roles for the EF-Tu, l-Asparaginase II and OmpT Proteins of Shiga Toxin-Producing Escherichia coli
    Microorganisms8, PubMed  Europe PubMed DOI
    8. 2019
  8. Feodorova,V.A., Lyapina,A.M., Zaitsev,S.S., Khizhnyakova,M.A., Sayapina,L.V., Ulianova,O.V., Ulyanov,S.S. and Motin,V.L.
    New promising targets for synthetic omptin-based peptide vaccine against Gram-negative pathogens
    Vaccines (Basel)7, PubMed  Europe PubMed DOI
  9. Liu,J., Mu,X., Wang,X., Huan,H., Gao,Q., Chen,J., Qiao,P., Jiang,L., Gao,S. and Liu,X.
    Unexpected transcriptome pompT' contributes to the increased pathogenicity of a pompT mutant of avian pathogenic Escherichia coli
    Vet Microbiol228, 61-68. PubMed  Europe PubMed DOI
    10. 2018
  10. Zhuge,X., Sun,Y., Xue,F., Tang,F., Ren,J., Li,D., Wang,J., Jiang,M. and Dai,J.
    A novel PhoP/PhoQ regulation pathway modulates the survival of extraintestinal pathogenic Escherichia coli in macrophages
    Front Immunol9, 788-788. PubMed  Europe PubMed DOI
    11. 2017
  11. Ueta,M., Wada,C., Bessho,Y., Maeda,M. and Wada,A.
    Ribosomal protein L31 in Escherichia coli contributes to ribosome subunit association and translation, whereas short L31 cleaved by protease 7 reduces both activities
    Genes Cells22, 452-471. PubMed  Europe PubMed DOI
  12. Wood,S.E., Sinsinbar,G., Gudlur,S., Nallani,M., Huang,C.F., Liedberg,B. and Mrksich,M.
    A bottom-up proteomic approach to identify substrate specificity of outer-membrane protease OmpT
    Angew Chem Int Ed Engl56, 16531-16535. PubMed  Europe PubMed DOI  P
    13. 2015
  13. Brannon,J.R., Thomassin,J.L., Gruenheid,S. and Le Moual,H.
    Antimicrobial peptide conformation as a structural determinant of omptin protease specificity
    J Bacteriol197, 3583-3591. PubMed  Europe PubMed DOI
  14. He,X.L., Wang,Q., Peng,L., Qu,Y.R., Puthiyakunnon,S., Liu,X.L., Hui,C.Y., Boddu,S., Cao,H. and Huang,S.H.
    Role of uropathogenic Escherichia coli outer membrane protein T in pathogenesis of urinary tract infection
    Pathog Dis73, PubMed  Europe PubMed DOI
    15. 2014
  15. Premjani,V., Tilley,D., Gruenheid,S., Le Moual,H. and Samis,J.A.
    Enterohemorrhagic Escherichia coli OmpT regulates outer membrane vesicle biogenesis
    FEMS Microbiol Lett355, 185-192. PubMed  Europe PubMed DOI
  16. Wan,L., Guo,Y., Hui,C.Y., Liu,X.L., Zhang,W.B., Cao,H. and Cao,H.
    The surface protease ompT serves as Escherichia coli K1 adhesin in binding to human brain micro vascular endothelial cells
    Pak J Pharm Sci27, 617-624. PubMed  Europe PubMed
    17. 2013
  17. Brannon,J.R., Thomassin,J.L., Desloges,I., Gruenheid,S. and Le Moual,H.
    Role of uropathogenic Escherichia coli OmpT in the resistance against human cathelicidin LL-37
    FEMS Microbiol Lett345, 64-71. PubMed  Europe PubMed DOI
  18. Lawrenz,M.B., Pennington,J. and Miller,V.L.
    Acquisition of omptin reveals cryptic virulence function of autotransporter YapE in Yersinia pestis
    Mol Microbiol89, 276-287. PubMed  Europe PubMed DOI
    19. 2012
  19. Dekker,N.
    Omptin
    [ISSN:978-0-12-407744-7]3, 284-289. DOI
  20. Thomassin,J.L., Brannon,J.R., Gibbs,B.F., Gruenheid,S. and Le Moual,H.
    OmpT outer membrane proteases of enterohemorrhagic and enteropathogenic Escherichia coli contribute differently to the degradation of human LL-37
    Infect Immun80, 483-492. PubMed  Europe PubMed DOI
  21. Wu,C., Tran,J.C., Zamdborg,L., Durbin,K.R., Li,M., Ahlf,D.R., Early,B.P., Thomas,P.M., Sweedler,J.V. and Kelleher,N.L.
    A protease for 'middle-down' proteomics
    Nat Methods9, 822-824. PubMed  Europe PubMed DOI
  22. Yoo,T.H., Pogson,M., Iverson,B.L. and Georgiou,G.
    Directed evolution of highly selective proteases by using a novel FACS-based screen that capitalizes on the p53 regulator MDM2
    Chembiochem13, 649-653. PubMed  Europe PubMed DOI
    23. 2010
  23. Hui,C., Guo,Y., Wu,S., Peng,L., Cao,H. and Huang,S.
    [In vitro function of outer membrane protease T of Escherichia coli K1 pathogenic strain]
    Wei Sheng Wu Xue Bao50, 48-53. PubMed  Europe PubMed
  24. Hui,C.Y., Guo,Y., He,Q.S., Peng,L., Wu,S.C., Cao,H. and Huang,S.H.
    Escherichia coli outer membrane protease OmpT confers resistance to urinary cationic peptides
    Microbiol Immunol54, 452-459. PubMed  Europe PubMed DOI
  25. Salunkhe,S.S., Raiker,V.A., Rewanwar,S., Kotwal,P., Kumar,A. and Padmanabhan,S.
    Enhanced fluorescent properties of an OmpT site deleted mutant of Green Fluorescent Protein
    Microb Cell Fact9, 26-26. PubMed  Europe PubMed DOI
  26. Zanfardino,A., Pizzo,E., Di Maro,A., Varcamonti,M. and D'Alessio,G.
    The bactericidal action on Escherichia coli of ZF-RNase-3 is triggered by the suicidal action of the bacterium OmpT protease
    FEBS J277, 1921-1928. PubMed  Europe PubMed DOI  P
    27. 2009
  27. Duche,D., Issouf,M. and Lloubes,R.
    Immunity protein protects colicin E2 from OmpT protease
    J Biochem145, 95-101. PubMed  Europe PubMed DOI
  28. Haiko,J., Suomalainen,M., Ojala,T., Lahteenmaki,K. and Korhonen,T.K.
    Invited review: Breaking barriers - attack on innate immune defences by omptin surface proteases of enterobacterial pathogens
    Innate Immun15, 67-80. PubMed  Europe PubMed DOI
  29. Le Sage,V., Zhu,L., LePage,C., Portt,A., Viau,C., Daigle,F., Gruenheid,S. and Le Moual,H.
    An outer membrane protease of the omptin family prevents activation of the Citrobacter rodentium PhoPQ two-component system by antimicrobial peptides
    Mol Microbiol74, 98-111. PubMed  Europe PubMed DOI
  30. Varadarajan,N., Pogson,M., Georgiou,G. and Iverson,B.L.
    Proteases that can distinguish among different post-translational forms of tyrosine engineered using multicolor flow cytometry
    J Am Chem Soc131, 18186-18190. PubMed  Europe PubMed DOI  P
  31. Yun,T.H., Cott,J.E., Tapping,R.I., Slauch,J.M. and Morrissey,J.H.
    Proteolytic inactivation of tissue factor pathway inhibitor by bacterial omptins
    Blood113, 1139-1148. PubMed  Europe PubMed DOI
    32. 2008
  32. Bishop,R.E.
    Structural biology of membrane-intrinsic beta-barrel enzymes: sentinels of the bacterial outer membrane
    Biochim Biophys Acta1778, 1881-1896. PubMed  Europe PubMed DOI
  33. Di Cera,E.
    Engineering protease specificity made simple, but not simpler
    Nat Chem Biol4, 270-271. PubMed  Europe PubMed DOI
  34. Neri,M., Baaden,M., Carnevale,V., Anselmi,C., Maritan,A. and Carloni,P.
    Microseconds dynamics simulations of the outer-membrane protease T
    Biophys J94, 71-78. PubMed  Europe PubMed DOI
  35. Varadarajan,N., Rodriguez,S., Hwang,B.Y., Georgiou,G. and Iverson,B.L.
    Highly active and selective endopeptidases with programmed substrate specificities
    Nat Chem Biol4, 290-294. PubMed  Europe PubMed DOI  P
    36. 2007
  36. Goonasekara,C.L., Gallivan,L.J., Jackman,D.M. and Heeley,D.H.
    Some binding properties of Omp T digested muscle tropomyosin
    J Muscle Res Cell Motil28, 175-182. PubMed  Europe PubMed DOI  P
  37. Ono,B., Kimiduka,H., Kubota,M., Okuno,K. and Yabuta,M.
    Role of the ompT Mutation in Stimulated Decrease in Colony-Forming Ability Due to Intracellular Protein Aggregate Formation in Escherichia coli Strain BL21
    Biosci Biotechnol Biochem71, 504-512. PubMed  Europe PubMed DOI
    38. 2006
  38. Neri,M., Anselmi,C., Carnevale,V., Vargiu,A.V. and Carloni,P.
    Molecular dynamics simulations of outer-membrane protease T from E. coli based on a hybrid coarse-grained/atomistic potential
    J Phys Condens Matter18, S347-S355.
    39. 2005
  39. Azzolini,S.S., Sasaki,S.D., Campos,I.T., Torquato,R.J., Juliano,M.A. and Tanaka,A.S.
    The role of HiTI, a serine protease inhibitor from Haematobia irritans irritans (Diptera: Muscidae) in the control of fly and bacterial proteases
    Exp Parasitol111, 30-36. PubMed  Europe PubMed DOI
  40. [YEAR:6-7-2005]Brandenburg,K., Garidel,P., Schromm,A.B., Andra,J., Kramer,A., Egmond,M. and Wiese,A.
    Investigation into the interaction of the bacterial protease OmpT with outer membrane lipids and biological activity of OmpT:lipopolysaccharide complexes
    Eur Biophys J34, 28-41. PubMed  Europe PubMed DOI
  41. [YEAR:10-5-2005]Varadarajan,N., Gam,J., Olsen,M.J., Georgiou,G. and Iverson,B.L.
    Engineering of protease variants exhibiting high catalytic activity and exquisite substrate selectivity
    Proc Natl Acad Sci U S A102, 6855-6860. PubMed  Europe PubMed DOI
    42. 2004
  42. [YEAR:17-8-2004]Baaden,M. and Sansom,M.S.
    OmpT: molecular dynamics simulations of an outer membrane enzyme
    Biophys J87, 2942-2953. PubMed  Europe PubMed DOI
  43. Dekker,N.
    Omptin
    [ISSN:0-12-079610-4]2, 212-216.  V
  44. Kukkonen,M. and Korhonen,T.K.
    The omptin family of enterobacterial surface proteases/adhesins: from housekeeping in Escherichia coli to systemic spread of Yersinia pestis
    Int J Med Microbiol294, 7-14. PubMed  Europe PubMed DOI
  45. Laird,M.W., Cope,K., Atkinson,R., Donahoe,M., Johnson,K. and Melick,M.
    Keratinocyte growth factor-2 production in an ompT-deficient Escherichia coli K-12 mutant
    Biotechnol Prog20, 44-50. PubMed  Europe PubMed DOI
  46. McCarter,J.D., Stephens,D., Shoemaker,K., Rosenberg,S., Kirsch,J.F. and Georgiou,G.
    Substrate specificity of the Escherichia coli outer membrane protease OmpT
    J Bacteriol186, 5919-5925. PubMed  Europe PubMed DOI  P
  47. Okuno,K., Yabuta,M., Ooi,T. and Kinoshita,S.
    Utilization of Escherichia coli outer-membrane endoprotease OmpT variants as processing enzymes for production of peptides from designer fusion proteins
    Appl Environ Microbiol70, 76-86. PubMed  Europe PubMed DOI
    48. 2002
  48. Kramer,R.A., Brandenburg,K., Vandeputte-Rutten,L., Werkhoven,M., Gros,P., Dekker,N. and Egmond,M.R.
    Lipopolysaccharide regions involved in the activation of Escherichia coli outer membrane protease OmpT
    Eur J Biochem269, 1746-1752. PubMed  Europe PubMed DOI
  49. Okuno,K., Yabuta,M., Kawanishi,K., Ohsuye,K., Ooi,T. and Kinoshita,S.
    Substrate specificity at the P1' site of Escherichia coli OmpT under denaturing conditions
    Biosci Biotechnol Biochem66, 127-134. PubMed  Europe PubMed DOI  P
  50. Okuno,K., Yabuta,M., Ohsuye,K., Ooi,T. and Kinoshita,S.
    An analysis of target preferences of Escherichia coli outer-membrane endoprotease OmpT for use in therapeutic peptide production: efficient cleavage of substrates with basic amino acids at the P4 and P6 positions
    Biotechnol Appl Biochem36, 77-84. PubMed  Europe PubMed DOI
    51. 2001
  51. [YEAR:13-2-2001]Dekker,N., Cox,R.C., Kramer,R.A. and Egmond,M.R.
    Substrate specificity of the integral membrane protease OmpT determined by spatially addressed peptide libraries
    Biochemistry40, 1694-1701. PubMed  Europe PubMed DOI
  52. [YEAR:21-9-2001]Kramer,R.A., Vandeputte-Rutten,L., De Roon,G.J., Gros,P., Dekker,N. and Egmond,M.R.
    Identification of essential acidic residues of outer membrane protease OmpT supports a novel active site
    FEBS Lett505, 426-430. PubMed  Europe PubMed DOI
  53. [YEAR:17-9-2001]Vandeputte-Rutten,L., Kramer,R.A., Kroon,J., Dekker,N., Egmond,M.R. and Gros,P.
    Crystal structure of the outer membrane protease OmpT from Escherichia coli suggests a novel catalytic site
    EMBO J20, 5033-5039. PubMed  Europe PubMed DOI  S
  54. [YEAR:16-1-2001]Yam,C.H., Siu,W.Y., Kaganovich,D., Ruderman,J.V. and Poon,R.Y.
    Cleavage of cyclin A at R70/R71 by the bacterial protease OmpT
    Proc Natl Acad Sci U S A98, 497-501. PubMed  Europe PubMed DOI
  55. [YEAR:15-12-2001]Yoo,J.H., Cheng,O.H. and Gerber,G.E.
    Determination of the native form of FadD, the Escherichia coli fatty acyl-CoA synthetase, and characterization of limited proteolysis by outer membrane protease OmpT
    Biochem J360, 699-706. PubMed  Europe PubMed DOI
    56. 2000
  56. Kramer,R.A., Zandwijken,D., Egmond,M.R. and Dekker,N.
    In vitro folding, purification and characterization of Escherichia coli outer membrane protease OmpT
    Eur J Biochem267, 885-893. PubMed  Europe PubMed DOI
  57. [YEAR:25-2-2000]Kramer,R.A., Dekker,N. and Egmond,M.R.
    Identification of active site serine and histidine residues in Escherichia coli outer membrane protease OmpT
    FEBS Lett468, 220-224. PubMed  Europe PubMed DOI
    58. 1998
  58. Stumpe,S., Schmid,R., Stephens,D.L., Georgiou,G. and Bakker,E.P.
    Identification of OmpT as the protease that hydrolyzes the antimicrobial peptide protamine before it enters growing cells of Escherichia coli
    J Bacteriol180, 4002-4006. PubMed  Europe PubMed
    59. 1996
  59. Pritchard,A.E., Dallmann,H.G. and McHenry,C.S.
    In vivo assembly of the tau-complex of the DNA polymerase III holoenzyme expressed from a five-gene artificial operon. Cleavage of the tau-complex to form a mixed gamma-tau-complex by the ompT protease
    J Biol Chem271, 10291-10298. PubMed  Europe PubMed
    60. 1995
  60. White,C.B., Chen,Q., Kenyon,G.L. and Babbitt,P.C.
    A novel activity of OmpT. Proteolysis under extreme denaturing conditions
    J Biol Chem270, 12990-12994. PubMed  Europe PubMed DOI
  61. Yabuta,M., Ochi,N. and Ohsuye,K.
    Hyperproduction of a recombinant fusion protein of Staphylococcus aureus V8 protease in Escherichia coli and its processing by OmpT protease to release an active V8 protease derivative
    Appl Microbiol Biotechnol44, 118-125. PubMed  Europe PubMed DOI  E
    62. 1994
  62. Henderson,T.A., Dombrosky,P.M. and Young,K.D.
    Artifactual processing of penicillin-binding proteins 7 and 1b by the OmpT protease of Escherichia coli
    J Bacteriol176, 256-259. PubMed  Europe PubMed
  63. Mangel,W.F., Toledo,D.L., Brown,M.T., Worzalla,K., Lee,M. and Dunn,J.J.
    Omptin: an Escherichia coli outer membrane proteinase that activates plasminogen
    Methods Enzymol244, 384-399. PubMed  Europe PubMed DOI  V
    64. 1993
  64. [YEAR:15-7-1993]Zhao,G.P. and Somerville,R.L.
    An amino acid switch (Gly281 - >Arg) within the "hinge" region of the tryptophan synthase beta subunit creates a novel cleavage site for the OmpT protease and selectively diminishes affinity toward a specific monoclonal antibody
    J Biol Chem268, 14912-14920. PubMed  Europe PubMed
    65. 1992
  65. Hanke,C., Hess,J., Schumacher,G. and Goebel,W.
    Processing by OmpT of fusion proteins carrying the HlyA transport signal during secretion by the Escherichia coli hemolysin transport system
    Mol Gen Genet233, 42-48. PubMed  Europe PubMed DOI
  66. [YEAR:1-10-1992]Lundrigan,M.D. and Webb,R.M.
    Prevalence of ompT among Escherichia coli isolates of human origin
    FEMS Microbiol Lett76, 51-56. PubMed  Europe PubMed
    67. 1990
  67. Cavard,D. and Lazdunski,C.
    Colicin cleavage by OmpT protease during both entry into and release from Escherichia coli cells
    J Bacteriol172, 648-652. PubMed  Europe PubMed  P
    68. 1989
  68. Grodberg,J. and Dunn,J.J.
    Comparison of Escherichia coli K-12 outer membrane protease ompT and Salmonella typhimurium E protein
    J Bacteriol171, 2903-2905. PubMed  Europe PubMed
    69. 1988
  69. Grodberg,J., Lundrigan,M.D., Toledo,D.L., Mangel,W.F. and Dunn,J.J.
    Complete nucleotide sequence and deduced amino acid sequence of the ompT gene of Escherichia coli K-12
    Nucleic Acids Res16, 1209-1209. PubMed  Europe PubMed
  70. Grodberg,J. and Dunn,J.J.
    ompT Encodes the Escherichia coli outer membrane protease that cleaves T7 RNA polymerase during purification
    J Bacteriol170, 1245-1253. PubMed  Europe PubMed
  71. Sugimura,K. and Nishihara,T.
    Purification, characterization, and primary structure of Escherichia coli protease VII with specificity for paired basic residues: identity of protease VII and OmpT
    J Bacteriol170, 5625-5632. PubMed  Europe PubMed  I
  72. Sugimura,K. and Higashi,N.
    A novel outer-membrane-associated protease in Escherichia coli
    J Bacteriol170, 3650-3654. PubMed  Europe PubMed  I
  73. [YEAR:16-6-1988]Sugimura,K.
    Mutant isolation and cloning of the gene encoding protease VII from Escherichia coli
    Biochem Biophys Res Commun153, 753-759. PubMed  Europe PubMed
    74. 1981
  74. Leytus,S.P., Bowles,L.K., Konisky,J. and Mangel,W.F.
    Activation of plasminogen to plasmin by a protease associated with the outer membrane of Escherichia coli
    Proc Natl Acad Sci U S A78, 1485-1489. PubMed  Europe PubMed

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