Literature for peptidase A01.068: necepsin-2

2022
1. Sharma,L., Pipil,S., Rawat,V.S. and Sehgal,N.
   Role of cathepsins B and D in proteolysis of yolk in the catfish Clarias gariepinus
   Fish Physiol Biochem48, 749-765. PubMed  Europe PubMed DOI
2021
2. Adegnika,A.A., de Vries,S.G., Zinsou,F.J., Honkepehedji,Y.J., Dejon Agobe,J.C., Vodonou,K.G., Bikangui,R., Bouyoukou Hounkpatin,A., Bache,E.B., Massinga Loembe,M., van Leeuwen,R., Molemans,M., Kremsner,P.G., Yazdanbakhsh,M., Hotez,P.J., Bottazzi,M.E., Li,G., Bethony,J.M., Diemert,D.J. and Grobusch,M.P.
   Safety and immunogenicity of co-administered hookworm vaccine candidates Na-GST-1 and Na-APR-1 in Gabonese adults: a randomised, controlled, double-blind, phase 1 dose-escalation trial
   Lancet Infect Dis21, 275-285. PubMed  Europe PubMed DOI
3. Huang,L., Wu,B.L., He,J.X., Zhang,Y., Chen,J. and Chen,X.J.
   Molecular characterization and functional analysis of the lysosomal cathepsin D-like gene in red swamp crayfish, Procambarus clarkii
   Genome1-11. PubMed  Europe PubMed DOI
2015
4. Fuaad,A.A., Pearson,M.S., Pickering,D.A., Becker,L., Zhao,G., Loukas,A.C., Skwarczynski,M. and Toth,I.
   Lipopeptide nanoparticles: development of vaccines against hookworm parasite
   ChemMedChem10, 1647-1654. PubMed  Europe PubMed DOI
5. Pearson,M.S., Jariwala,A.R., Abbenante,G., Plieskatt,J., Wilson,D., Bottazzi,M.E., Hotez,P.J., Keegan,B., Bethony,J.M. and Loukas,A.
   New tools for NTD vaccines: a case study of quality control assays for product development of the human hookworm vaccine Na-APR-1M74
   Hum Vaccin Immunother11, 1251-1257. PubMed  Europe PubMed DOI
6. Seid,C.A., Curti,E., Jones,R.M., Hudspeth,E., Rezende,W., Pollet,J., Center,L., Versteeg,L., Pritchard,S., Musiychuk,K., Yusibov,V., Hotez,P.J. and Bottazzi,M.E.
   Expression, purification, and characterization of the Necator americanus aspartic protease-1 (Na-APR-1 (M74)) antigen, a component of the bivalent human hookworm vaccine
   Hum Vaccin Immunother11, 1474-1488. PubMed  Europe PubMed DOI
2013
7. Wasyl,K., Zawistowska-Deniziak,A., Baska,P., Wedrychowicz,H. and Wisniewski,M.
   Molecular cloning and expression of the cDNA sequence encoding a novel aspartic protease from Uncinaria stenocephala
   Exp Parasitol134, 220-227. PubMed  Europe PubMed DOI
2012
8. Dougall,A.M., Pearson,M.S. and Loukas,A.
   Na-APR-1 (aka Necepsin-2)
   [ISSN:978-0-12-407744-7]3, 113-118. DOI
9. Ni,F., Xu,S.S., Zhang,S.L., Xu,C.M. and Luo,D.M.
   [Cloning and expression of D-like aspartic protease of Anisakis simplex]
   Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi30, 294-298. PubMed  Europe PubMed
10. Park,J.N., Park,S.K., Cho,M.K., Park,M.K., Kang,S.A., Kim,D.H. and Yu,H.S.
    Molecular characterization of 45kDa aspartic protease of Trichinella spiralis
    Vet Parasitol190, 510-518. PubMed  Europe PubMed DOI
2010
11. Pearson,M.S., Pickering,D.A., Tribolet,L., Cooper,L., Mulvenna,J., Oliveira,L.M., Bethony,J.M., Hotez,P.J. and Loukas,A.
    Neutralizing antibodies to the hookworm hemoglobinase Na-APR-1: implications for a multivalent vaccine against hookworm infection and schistosomiasis
    J Infect Dis201, 1561-1569. PubMed  Europe PubMed DOI
2009
12. Fragoso,R.R., Lourenco,I.T., Batista,J.A., Oliveira-Neto,O.B., Silva,M.C., Rocha,T.L., Coutinho,M.V. and Grossi-de-Sa,M.F.
    Meloidogyne incognita: molecular cloning and characterization of a cDNA encoding a cathepsin D-like aspartic proteinase
    Exp Parasitol121, 115-123. PubMed  Europe PubMed DOI
13. Ranjit,N., Zhan,B., Hamilton,B., Stenzel,D., Lowther,J., Pearson,M., Gorman,J., Hotez,P. and Loukas,A.
    Proteolytic degradation of hemoglobin in the intestine of the human hookworm Necator americanus
    J Infect Dis199, 904-912. PubMed  Europe PubMed DOI
14. Yang,Y., Wei,H., Qin,W. and Zheng,J.
    Expression and characterization of aspartic protease gene in eggs and larvae stage of Ancylostoma caninum
    Parasitol Res104, 1327-1333. PubMed  Europe PubMed DOI
2005
15. Loukas,A., Bethony,J.M., Mendez,S., Fujiwara,R.T., Goud,G.N., Ranjit,N., Zhan,B., Jones,K., Bottazzi,M.E. and Hotez,P.J.
    Vaccination with recombinant aspartic hemoglobinase reduces parasite load and blood loss after hookworm infection in dogs
    PLoS Medicine2, e295-e295. PubMed  Europe PubMed DOI
2004
16. Goud,G.N., Zhan,B., Ghosh,K., Loukas,A., Hawdon,J., Dobardzic,A., Deumic,V., Liu,S., Dobardzic,R., Zook,B.C., Jin,Q., Liu,Y., Hoffman,L., Chung-Debose,S., Patel,R., Mendez,S. and Hotez,P.J.
    Cloning, yeast expression, isolation, and vaccine testing of recombinant Ancylostoma-secreted protein (ASP)-1 and ASP-2 from Ancylostoma ceylanicum
    J Infect Dis189, 919-929. PubMed  Europe PubMed DOI
17. Jolodar,A., Fischer,P., Buttner,D.W., Miller,D.J., Schmetz,C. and Brattig,N.W.
    Onchocerca volvulus: expression and immunolocalization of a nematode cathepsin D-like lysosomal aspartic protease
    Exp Parasitol107, 145-156. PubMed  Europe PubMed DOI
2003
18. [YEAR:1-2-2003]Williamson,A.L., Brindley,P.J., Abbenante,G., Datu,B.J., Prociv,P., Berry,C., Girdwood,K., Pritchard,D.I., Fairlie,D.P., Hotez,P.J., Zhan,B. and Loukas,A.
    Hookworm aspartic protease, Na-APR-2, cleaves human hemoglobin and serum proteins in a host-specific fashion
    J Infect Dis187, 484-494. PubMed  Europe PubMed DOI
19. Williamson,A.L., Brindley,P.J. and Loukas,A.
    Hookworm cathepsin D aspartic proteases: contributing roles in the host-specific degradation of serum proteins and skin macromolecules
    Parasitology126, 179-185. PubMed  Europe PubMed DOI
2002
20. [YEAR:31-10-2002]Syntichaki,P., Xu,K., Driscoll,M. and Tavernarakis,N.
    Specific aspartyl and calpain proteases are required for neurodegeneration in C. elegans
    Nature419, 939-944. PubMed  Europe PubMed DOI
21. Williamson,A.L., Brindley,P.J., Abbenante,G., Prociv,P., Berry,C., Girdwood,K., Pritchard,D.I., Fairlie,D.P., Hotez,P.J., Dalton,J.P. and Loukas,A.
    Cleavage of hemoglobin by hookworm cathepsin D aspartic proteases and its potential contribution to host specificity
    FASEB J16, 1458-1460. PubMed  Europe PubMed DOI
2000
22. [YEAR:25-8-2000]Tcherepanova,I., Bhattacharyya,L., Rubin,C.S. and Freedman,J.H.
    Aspartic proteases from the nematode Caenorhabditis elegans. Structural organization and developmental and cell-specific expression of asp-1
    J Biol Chem275, 26359-26369. PubMed  Europe PubMed DOI
1999
23. Brown,A., Girod,N., Billett,E.E. and Pritchard,D.I.
    Necator americanus (human hookworm) aspartyl proteinases and digestion of skin macromolecules during skin penetration
    Am J Trop Med Hyg60, 840-847. PubMed  Europe PubMed
24. Geier,G., Banaj,H.J., Heid,H., Bini,L., Pallini,V. and Zwilling,R.
    Aspartyl proteases in Caenorhabditis elegans. Isolation, identification and characterization by a combined use of affinity chromatography, two-dimensional gel electrophoresis, microsequencing and databank analysis
    Eur J Biochem264, 872-879. PubMed  Europe PubMed DOI
1998
25. [YEAR:15-1-1998]Jolodar,A. and Miller,D.J.
    Identification of a novel family of non-lysosomal aspartic proteases in nematodes
    Biochim Biophys Acta1382, 13-16. PubMed  Europe PubMed DOI
1997
26. Jolodar,A. and Miller,D.J.
    Preliminary characterisation of an Onchocerca volvulus aspartic protease
    Int J Parasitol27, 1087-1090. PubMed  Europe PubMed DOI
1996
27. Harrop,S.A., Prociv,P. and Brindley,P.J.
    Acasp, a gene encoding a cathepsin D-like aspartic protease from the hookworm Ancylostoma caninum
    Biochem Biophys Res Commun227, 294-302. PubMed  Europe PubMed DOI
1995
28. Sato,K., Nagai,Y. and Suzuki,M.
    Purification and characterization of an acid proteinase from Dirofilaria immitis worms
    Adv Exp Med Biol362, 299-304. PubMed  Europe PubMed
29. Sato,K., Yamaguchi,H., Waki,S., Suzuki,M. and Nagai,Y.
    Dirofilaria immitis: immunohistochemical localization of acid proteinase in the adult worm
    Exp Parasitol81, 63-71. PubMed  Europe PubMed DOI
1993
30. Sato,K., Nagai,Y. and Suzuki,M.
    Purification and partial characterization of an acid proteinase from Dirofilaria immitis
    Mol Biochem Parasitol58, 293-299. PubMed  Europe PubMed DOI