Literature for peptidase A01.061: candidapepsin SAP3

Summary Alignment Sequences Sequence features Distribution Structure Literature Substrates

(Topics flags: S Structure, P Specificity, I Inhibitor. To select only the references relevant to a single topic, click the link above. See explanation.)

    2015
  1. Kozik,A., Gogol,M., Bochenska,O., Karkowska-Kuleta,J., Wolak,N., Kamysz,W., Aoki,W., Ueda,M., Faussner,A. and Rapala-Kozik,M.<br>Kinin release from human kininogen by 10 aspartic proteases produced by pathogenic yeast Candida albicans<br>BMC Microbiol (2015) 15, 60-60. PubMed  Europe PubMed DOI
  2. 2013
  3. Cadicamo,C.D., Mortier,J., Wolber,G., Hell,M., Heinrich,I.E., Michel,D., Semlin,L., Berger,U., Korting,H.C., Holtje,H.D., Koksch,B. and Borelli,C.<br>Design, synthesis, inhibition studies, and molecular modeling of pepstatin analogues addressing different secreted aspartic proteinases of Candida albicans<br>Biochem Pharmacol (2013) 85, 881-887. PubMed  Europe PubMed DOI  I
  4. 2012
  5. Monod,M., Staib,P. and Borelli,C.<br>Candidapepsin<br>[ISSN:978-0-12-407744-7] (2012) 3, 159-166. DOI
  6. 2011
  7. Aoki,W., Kitahara,N., Miura,N., Morisaka,H., Yamamoto,Y., Kuroda,K. and Ueda,M.<br>Comprehensive characterization of secreted aspartic proteases encoded by a virulence gene family in Candida albicans<br>J Biochem (2011) 150, 431-438. PubMed  Europe PubMed DOI  P
  8. Buchold,C., Hemberger,Y., Heindl,C., Welker,A., Degel,B., Pfeuffer,T., Staib,P., Schneider,S., Rosenthal,P.J., Gut,J., Morschhauser,J., Bringmann,G. and Schirmeister,T.<br>New cis-configured aziridine-2-carboxylates as aspartic acid protease inhibitors<br>ChemMedChem (2011) 6, 141-152. PubMed  Europe PubMed DOI  I
  9. 2010
  10. Correia,A., Lermann,U., Teixeira,L., Cerca,F., Botelho,S., Gil Da Costa,R.M., Sampaio,P., Gartner,F., Morschhauser,J., Vilanova,M. and Pais,C.<br>Limited role of secreted aspartyl proteinases Sap1 to Sap6 in Candida albicans virulence and host immune response in murine hematogenously disseminated candidiasis<br>Infect Immun (2010) 78, 4839-4849. PubMed  Europe PubMed DOI
  11. Pietrella,D., Rachini,A., Pandey,N., Schild,L., Netea,M., Bistoni,F., Hube,B. and Vecchiarelli,A.<br>The Inflammatory response induced by aspartic proteases of Candida albicans is independent of proteolytic activity<br>Infect Immun (2010) 78, 4754-4762. PubMed  Europe PubMed DOI
  12. 2009
  13. Gropp,K., Schild,L., Schindler,S., Hube,B., Zipfel,P.F. and Skerka,C.<br>The yeast Candida albicans evades human complement attack by secretion of aspartic proteases<br>Mol Immunol (2009) 47, 465-475. PubMed  Europe PubMed DOI
  14. Parra-Ortega,B., Cruz-Torres,H., Villa-Tanaca,L. and Hernandez-Rodriguez,C.<br>Phylogeny and evolution of the aspartyl protease family from clinically relevant Candida species<br>Mem Inst Oswaldo Cruz (2009) 104, 505-512. PubMed  Europe PubMed
  15. 2008
  16. Lermann,U. and Morschhauser,J.<br>Secreted aspartic proteases are not required for invasion of reconstituted human epithelia by Candida albicans<br>Microbiology (Reading) (2008) 154, 3281-3295. PubMed  Europe PubMed DOI
  17. Naglik,J.R., Moyes,D., Makwana,J., Kanzaria,P., Tsichlaki,E., Weindl,G., Tappuni,A.R., Rodgers,C.A., Woodman,A.J., Challacombe,S.J., Schaller,M. and Hube,B.<br>Quantitative expression of the Candida albicans secreted aspartyl proteinase gene family in human oral and vaginal candidiasis<br>Microbiology (Reading) (2008) 154, 3266-3280. PubMed  Europe PubMed DOI  PMC  EPMC
  18. Odds,F.C.<br>Secreted proteinases and Candida albicans virulence<br>Microbiology (Reading) (2008) 154, 3245-3246. PubMed  Europe PubMed DOI
  19. Staib,P., Lermann,U., Blass-Warmuth,J., Degel,B., Wurzner,R., Monod,M., Schirmeister,T. and Morschhauser,J.<br>Tetracycline-inducible expression of individual secreted aspartic proteases in Candida albicans allows isoenzyme-specific inhibitor screening<br>Antimicrob Agents Chemother (2008) 52, 146-156. PubMed  Europe PubMed DOI  PMC  EPMC
  20. 2007
  21. Borelli,C., Ruge,E., Schaller,M., Monod,M., Korting,H.C., Huber,R. and Maskos,K.<br>The crystal structure of the secreted aspartic proteinase 3 from Candida albicans and its complex with pepstatin A<br>Proteins (2007) 68, 738-748. PubMed  Europe PubMed DOI  S  I
  22. 2003
  23. Korting,H.C., Hube,B., Oberbauer,S., Januschke,E., Hamm,G., Albrecht,A., Borelli,C. and Schaller,M.<br>Reduced expression of the hyphal-independent Candida albicans proteinase genes SAP1 and SAP3 in the efg1 mutant is associated with attenuated virulence during infection of oral epithelium<br>J Med Microbiol (2003) 52, 623-632. PubMed  Europe PubMed DOI
  24. 2002
  25. Felk,A., Kretschmar,M., Albrecht,A., Schaller,M., Beinhauer,S., Nichterlein,T., Sanglard,D., Korting,H.C., Schafer,W. and Hube,B.<br>Candida albicans hyphal formation and the expression of the Efg1-regulated proteinases Sap4 to Sap6 are required for the invasion of parenchymal organs<br>Infect Immun (2002) 70, 3689-3700. PubMed  Europe PubMed DOI  PMC  EPMC
  26. Kretschmar,M., Felk,A., Staib,P., Schaller,M., Hess,D., Callapina,M., Morschhauser,J., Schafer,W., Korting,H.C., Hof,H., Hube,B. and Nichterlein,T.<br>Individual acid aspartic proteinases (Saps) 1-6 of Candida albicans are not essential for invasion and colonization of the gastrointestinal tract in mice<br>Microb Pathog (2002) 32, 61-70. PubMed  Europe PubMed DOI
  27. 2001
  28. De Bernardis,F., Sullivan,P.A. and Cassone,A.<br>Aspartyl proteinases of Candida albicans and their role in pathogenicity<br>Med Mycol (2001) 39, 303-313. PubMed  Europe PubMed
  29. Schaller,M., Januschke,E., Schackert,C., Woerle,B. and Korting,H.C.<br>Different isoforms of secreted aspartyl proteinases (Sap) are expressed by Candida albicans during oral and cutaneous candidosis in vivo<br>J Med Microbiol (2001) 50, 743-747. PubMed  Europe PubMed
  30. 2000
  31. [YEAR:14-7-2000]Koelsch,G., Tang,J., Loy,J.A., Monod,M., Jackson,K., Foundling,S.I. and Lin,X.L.<br>Enzymic characteristics of secreted aspartic proteases of Candida albicans<br>Biochim Biophys Acta (14-7-2000) 1480, 117-131. PubMed  Europe PubMed DOI
  32. Schaller,M., Schackert,C., Korting,H.C., Januschke,E. and Hube,B.<br>Invasion of Candida albicans correlates with expression of secreted aspartic proteinases during experimental infection of human epidermis<br>J Invest Dermatol (2000) 114, 712-717. PubMed  Europe PubMed DOI
  33. Stehr,F., Felk,A., Kretschmar,M., Schaller,M., Schafer,W. and Hube,B.<br>[Extracellular hydrolytic enzymes and their relevance during Candida albicans infections]<br>Mycoses (2000) 43 Suppl 2, 17-21. PubMed  Europe PubMed
  34. 1999
  35. Borg-von Zepelin,M., Meyer,I., Thomssen,R., Wurzner,R., Sanglard,D., Telenti,A. and Monod,M.<br>HIV-protease inhibitors reduce cell adherence of Candida albicans strains by inhibition of yeast secreted aspartic proteases<br>J Invest Dermatol (1999) 113, 747-751. PubMed  Europe PubMed DOI  I
  36. Kretschmar,M., Hube,B., Bertsch,T., Sanglard,D., Merker,R., Schroder,M., Hof,H. and Nichterlein,T.<br>Germ tubes and proteinase activity contribute to virulence of Candida albicans in murine peritonitis<br>Infect Immun (1999) 67, 6637-6642. PubMed  Europe PubMed  PMC  EPMC
  37. Monod,M., Borg-von Zepelin,M., Telenti,A. and Sanglard,D.<br>The inhibition of Candida-albicans-secreted aspartic proteases by three different HIV protease inhibitors<br>Dermatology (1999) 198, 412-414. PubMed  Europe PubMed  I
  38. Schaller,M., Korting,H.C., Schafer,W., Bastert,J., Chen,W. and Hube,B.<br>Secreted aspartic proteinase (Sap) activity contributes to tissue damage in a model of human oral candidosis<br>Mol Microbiol (1999) 34, 169-180. PubMed  Europe PubMed DOI
  39. 1997
  40. Hube,B., Sanglard,D., Odds,F.C., Hess,D., Monod,M., Schafer,W., Brown,A.J. and Gow,N.A.<br>Disruption of each of the secreted aspartyl proteinase genes SAP1, SAP2, and SAP3 of Candida albicans attenuates virulence<br>Infect Immun (1997) 65, 3529-3538. PubMed  Europe PubMed  PMC  EPMC
  41. Smolenski,G., Sullivan,P.A., Cutfield,S.M. and Cutfield,J.F.<br>Analysis of secreted aspartic proteinases from Candida albicans: purification and characterization of individual Sap1, Sap2 and Sap3 isoenzymes<br>Microbiology (Reading, Engl.) (1997) 143, 349-356. PubMed  Europe PubMed
  42. 1994
  43. Hube,B., Monod,M., Schofield,D.A., Brown,A.J. and Gow,N.A.<br>Expression of seven members of the gene family encoding secretory aspartyl proteinases in Candida albicans<br>Mol Microbiol (1994) 14, 87-99. PubMed  Europe PubMed DOI
  44. Monod,M., Togni,G., Hube,B. and Sanglard,D.<br>Multiplicity of genes encoding secreted aspartic proteinases in Candida species<br>Mol Microbiol (1994) 13, 357-368. PubMed  Europe PubMed DOI
  45. 1993
  46. White,T.C., Miyasaki,S.H. and Agabian,N.<br>Three distinct secreted aspartyl proteinases in Candida albicans<br>J Bacteriol (1993) 175, 6126-6133. PubMed  Europe PubMed  PMC  EPMC