Literature for peptidase A01.046: napsin A

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Literature Substrates

(Topics flags: A Assay, P Specificity, K Knockout, I Inhibitor, L Localization, V Review, U Therapeutic. To select only the references relevant to a single topic, click the link above. See explanation.)

    2024
  1. Al-Hussaini,M., Talia,K.L. and McCluggage,W.G.
    Napsin A Immunoreactivity in "Hobnail" Epithelium in Benign Endometrial and Endocervical Polyps
    Int J Gynecol Pathol44, 31-36. PubMed  Europe PubMed DOI
  2. Larose,C., Leduc,C. and Chevrier,M.
    Napsin-A Immunohistochemistry in the Diagnosis of Pulmonary Alveolar Proteinosis
    Arch Pathol Lab Med PubMed  Europe PubMed DOI
  3. 2020
  4. Bulutay,P., Akyurek,N. and Memis,L.
    Clinicopathological and Prognostic Significance of the EML4-ALK Translocation and IGFR1, TTF1, Napsin A Expression in Patients with Lung Adenocarcinoma
    Turk Patoloji Derg PubMed  Europe PubMed DOI
  5. Stotz,S., Bleher,D., Kalbacher,H. and Maurer,A.
    Grassystatin-derived peptides selectively inhibit cathepsin E and have low affinity to cathepsin D
    Biochem Biophys Res Commun527, 238-241. PubMed  Europe PubMed DOI  I
  6. Wang,X., Wendel,J.R.H., Emerson,R.E., Broaddus,R.R., Creighton,C.J., Rusch,D.B., Buechlein,A., DeMayo,F.J., Lydon,J.P. and Hawkins,S.M.
    Pten and Dicer1 loss in the mouse uterus causes poorly differentiated endometrial adenocarcinoma
    Oncogene39, 6286-6299. PubMed  Europe PubMed DOI
  7. 2019
  8. Maurer,A. and Kalbacher,H.
    Pepstatin pull-down at high pH is a powerful tool for detection and analysis of napsin A
    Biochem Biophys Res Commun515, 145-148. PubMed  Europe PubMed DOI  I
  9. 2018
  10. Zhou,L., Lv,X., Yang,J., Zhu,Y., Wang,Z. and Xu,T.
    Overexpression of napsin A resensitizes drug-resistant lung cancer A549 cells to gefitinib by inhibiting EMT
    Oncol Lett16, 2533-2538. PubMed  Europe PubMed DOI
  11. 2015
  12. Rekhtman,N. and Kazi,S.
    Nonspecific reactivity of polyclonal napsin A antibody in mucinous adenocarcinomas of various sites: a word of caution
    Arch Pathol Lab Med139, 434-436. PubMed  Europe PubMed DOI
  13. 2014
  14. Kandalaft,P.L., Gown,A.M. and Isacson,C.
    The lung-restricted marker napsin A is highly expressed in clear cell carcinomas of the ovary
    Am J Clin Pathol142, 830-836. PubMed  Europe PubMed DOI
  15. Kobel,M. and Duggan,M.A.
    Napsin A: another milestone in the subclassification of ovarian carcinoma
    Am J Clin Pathol142, 735-737. PubMed  Europe PubMed DOI
  16. Xu,B., Abourbih,S., Sircar,K., Kassouf,W., Aprikian,A., Tanguay,S. and Brimo,F.
    Diagnostic and prognostic role of immunohistochemical expression of napsin-A aspartic peptidase in clear cell and papillary renal cell carcinoma: a study including 233 primary and metastatic cases
    Appl Immunohistochem Mol Morphol22, 206-212. PubMed  Europe PubMed DOI
  17. 2013
  18. Aulakh,K.S., Chisholm,C.D., Smith,D.A. and Speights,V.O.
    TTF-1 and napsin A do not differentiate metastatic lung adenocarcinomas from primary esophageal adenocarcinomas: proposal of a novel staining panel
    Arch Pathol Lab Med137, 1094-1098. PubMed  Europe PubMed DOI
  19. Chernock,R.D., El-Mofty,S.K., Becker,N. and Lewis,J.S., Jr.
    Napsin A expression in anaplastic, poorly differentiated, and micropapillary pattern thyroid carcinomas
    Am J Surg Pathol37, 1215-1222. PubMed  Europe PubMed DOI
  20. 2012
  21. Noh,S. and Shim,H.
    Optimal combination of immunohistochemical markers for subclassification of non-small cell lung carcinomas: a tissue microarray study of poorly differentiated areas
    Lung Cancer76, 51-55. PubMed  Europe PubMed DOI
  22. Ordonez,N.G.
    Napsin A expression in lung and kidney neoplasia: a review and update
    Adv Anat Pathol19, 66-73. PubMed  Europe PubMed DOI
  23. Ordonez,N.G.
    A Word of Caution Regarding Napsin A Expression in Squamous Cell Carcinomas of the Lung
    Am J Surg Pathol36, 396-401. PubMed  Europe PubMed DOI
  24. Turner,B.M., Cagle,P.T., Sainz,I.M., Fukuoka,J., Shen,S.S. and Jagirdar,J.
    Napsin A, a new marker for lung adenocarcinoma, is complementary and more sensitive and specific than thyroid transcription factor 1 in the differential diagnosis of primary pulmonary carcinoma: evaluation of 1674 cases by tissue microarray
    Arch Pathol Lab Med136, 163-171. PubMed  Europe PubMed DOI
  25. Ueno,T.
    Napsin A
    [ISSN:978-0-12-407744-7]3, 69-71. DOI
  26. Ye,J., Hameed,O., Findeis-Hosey,J., Fan,L., Li,F., McMahon,L., Yang,Q., Wang,H. and Xu,H.
    Diagnostic utility of PAX8, TTF-1 and napsin A for discriminating metastatic carcinoma from primary adenocarcinoma of the lung
    Biotech Histochem87, 30-34. PubMed  Europe PubMed DOI
  27. Zheng,J.X., Guan,S.H., Xu,Q., Liu,J.Z. and Song,P.
    Inhibition of epithelial-mesenchymal transition in A549 cell by transfected napsin A
    Chin Med J (Engl)125, 2734-2740. PubMed  Europe PubMed DOI
  28. 2011
  29. Fatima,N., Cohen,C., Lawson,D. and Siddiqui,M.T.
    TTF-1 and napsin A double stain: a useful marker for diagnosing lung adenocarcinoma on fine-needle aspiration cell blocks
    Cancer Cytopathol119, 127-133. PubMed  Europe PubMed DOI  L
  30. Kuwata,T., Iwata,T. and Iwanami,T.
    Napsin A and thyroid transcription factor-1-positive cerebellar tumor with epidermal growth factor receptor mutation
    Case Rep Oncol4, 564-568. PubMed  Europe PubMed DOI
  31. Wu,Z.Z., Sun,N.K., Chien,K.Y. and Chao,C.C.
    Silencing of the SNARE protein NAPA sensitizes cancer cells to cisplatin by inducing ERK1/2 signaling, synoviolin ubiquitination and p53 accumulation
    Biochem Pharmacol82, 1630-1640. PubMed  Europe PubMed DOI  K
  32. Ye,J., Findeis-Hosey,J.J., Yang,Q., McMahon,L.A., Yao,J.L., Li,F. and Xu,H.
    Combination of napsin A and TTF-1 immunohistochemistry helps in differentiating primary lung adenocarcinoma from metastatic carcinoma in the lung
    Appl Immunohistochem Mol Morphol19, 313-317. PubMed  Europe PubMed DOI
  33. 2010
  34. Bishop,J.A., Sharma,R. and Illei,P.B.
    Napsin A and thyroid transcription factor-1 expression in carcinomas of the lung, breast, pancreas, colon, kidney, thyroid, and malignant mesothelioma
    Hum Pathol41, 20-25. PubMed  Europe PubMed DOI
  35. Nishimura,T., Nomura,M., Tojo,H., Hamasaki,H., Fukuda,T., Fujii,K., Mikami,S., Bando,Y. and Kato,H.
    Proteomic analysis of laser-microdissected paraffin-embedded tissues: (2) MRM assay for stage-related proteins upon non-metastatic lung adenocarcinoma
    J Proteomics73, 1100-1110. PubMed  Europe PubMed DOI
  36. Raspollini,M.R., Comin,C.E., Crisci,A. and Chilosi,M.
    The use of placental S100 (S100P), GATA3 and napsin A in the differential diagnosis of primary adenocarcinoma of the bladder and bladder metastasis from adenocarcinoma of the lung
    Pathologica102, 33-35. PubMed  Europe PubMed
  37. Stoll,L.M., Johnson,M.W., Gabrielson,E., Askin,F., Clark,D.P. and Li,Q.K.
    The utility of napsin-A in the identification of primary and metastatic lung adenocarcinoma among cytologically poorly differentiated carcinomas
    Cancer Cytopathol118, 441-449. PubMed  Europe PubMed DOI
  38. Zheng,J.X., Guan,S.H., Xu,Q., Tang,Y., Liu,J.Z. and Lu,X.T.
    [Effect of napsin A transfection into type II alveolar epithelial cells on pulmonary fibrosis]
    Zhonghua Yi Xue Za Zhi90, 3294-3299. PubMed  Europe PubMed  U
  39. 2008
  40. Ueno,T., Elmberger,G., Weaver,T.E., Toi,M. and Linder,S.
    The aspartic protease napsin A suppresses tumor growth independent of its catalytic activity
    Lab Invest88, 256-263. PubMed  Europe PubMed DOI
  41. Woischnik,M., Bauer,A., Aboutaam,R., Pamir,A., Stanzel,F., de Blic,J. and Griese,M.
    Cathepsin H and napsin A are active in the alveoli and increased in alveolar proteinosis
    Eur Respir J31, 1197-1204. PubMed  Europe PubMed DOI
  42. 2007
  43. Dejmek,A., Naucler,P., Smedjeback,A., Kato,H., Maeda,M., Yashima,K., Maeda,J. and Hirano,T.
    Napsin A (TA02) is a useful alternative to thyroid transcription factor-1 (TTF-1) for the identification of pulmonary adenocarcinoma cells in pleural effusions
    Diagn Cytopathol35, 493-497. PubMed  Europe PubMed DOI
  44. 2004
  45. Giller,T. and Schauer-Vukasinovic,V.
    Napsin A
    [ISSN:0-12-079610-4]2, 52-53.  V
  46. [YEAR:16-4-2004]Ueno,T., Linder,S., Na,C.L., Rice,W.R., Johansson,J. and Weaver,T.E.
    Processing of pulmonary surfactant protein B by napsin and cathepsin H
    J Biol Chem279, 16178-16184. PubMed  Europe PubMed DOI  P
  47. 2003
  48. [YEAR:5-12-2003]Brasch,F., Ochs,M., Kahne,T., Guttentag,S., Schauer-Vukasinovic,V., Derrick,M., Johnen,G., Kapp,N., Muller,K.M., Richter,J., Giller,T., Hawgood,S. and Buhling,F.
    Involvement of napsin A in the C- and N-terminal processing of surfactant protein B in type-II pneumocytes of the human lung
    J Biol Chem278, 49006-49014. PubMed  Europe PubMed DOI
  49. Cronshaw,R.F., Schauer-Vukasinovic,V., Powell,D.J., Giller,T., Bur,D. and Kay,J.
    Inhibition of human napsin A
    Protein Pept Lett10, 35-42. PubMed  Europe PubMed DOI
  50. Hirano,T., Gong,Y., Yoshida,K., Kato,Y., Yashima,K., Maeda,M., Nakagawa,A., Fujioka,K., Ohira,T., Ikeda,N., Ebihara,Y., Auer,G. and Kato,H.
    Usefulness of TA02 (napsin A) to distinguish primary lung adenocarcinoma from metastatic lung adenocarcinoma
    Lung Cancer41, 155-162. PubMed  Europe PubMed DOI
  51. [YEAR:22-4-2003]Ueno,T., Linder,S. and Elmberger,G.
    Aspartic proteinase napsin is a useful marker for diagnosis of primary lung adenocarcinoma
    Br J Cancer88, 1229-1233. PubMed  Europe PubMed DOI
  52. 2002
  53. [YEAR:19-8-2002]Cook,M., Buhling,F., Ansorge,S., Tatnell,P.J. and Kay,J.
    Pronapsin A and B gene expression in normal and malignant human lung and mononuclear blood cells
    Biochim Biophys Acta1577, 10-16. PubMed  Europe PubMed DOI
  54. 2001
  55. Mori,K., Kon,Y., Konno,A. and Iwanaga,T.
    Cellular distribution of napsin (kidney-derived aspartic protease-like protein, KAP) mRNA in the kidney, lung and lymphatic organs of adult and developing mice
    Arch Histol Cytol64, 319-327. PubMed  Europe PubMed
  56. [YEAR:15-11-2001]Schauer-Vukasinovic,V., Langen,H. and Giller,T.
    Detection of immunoreactive napsin A in human urine
    Biochim Biophys Acta1524, 51-56. PubMed  Europe PubMed DOI
  57. 2000
  58. Hirano,T., Auer,C., Maeda,M., Hagiwara,Y., Okada,S., Ohira,T., Okuzawa,K., Fujioka,K., Franzen,B., Hibi,N., Seito,T., Ebihara,Y. and Kato,H.
    Human tissue distribution of TA02, which is homologous with a new type of aspartic proteinase, napsin A
    Jpn J Cancer Res91, 1015-1021. PubMed  Europe PubMed
  59. Rosse,G., Kueng,E., Page,M.G., Schauer-Vukasinovic,V., Giller,T., Lahm,H.W., Hunziker,P. and Schlatter,D.
    Rapid identification of substrates for novel proteases using a combinatorial peptide library
    J Comb Chem2, 461-466. PubMed  Europe PubMed  A
  60. Schauer-Vukasinovic,V., Bur,D., Kitas,E., Schlatter,D., Rosse,G., Lahm,H.W. and Giller,T.
    Purification and characterization of active recombinant human napsin A
    Eur J Biochem267, 2573-2580. PubMed  Europe PubMed DOI
  61. [YEAR:21-6-2000]Schauer-Vukasinovic,V., Wright,M.B., Breu,V. and Giller,T.
    Cloning, expression and functional characterization of rat napsin
    Biochim Biophys Acta1492, 207-210. PubMed  Europe PubMed DOI
  62. Tatnell,P.J., Cook,M., Peters,C. and Kay,J.
    Molecular organization, expression and chromosomal localization of the mouse pronapsin gene
    Eur J Biochem267, 6921-6930. PubMed  Europe PubMed DOI
  63. 1999
  64. [YEAR:26-11-1999]Chuman,Y., Bergman,A., Ueno,T., Saito,S., Sakaguchi,K., Alaiya,A.A., Franzen,B., Bergman,T., Arnott,D., Auer,G., Appella,E., Jornvall,H. and Linder,S.
    Napsin A, a member of the aspartic protease family, is abundantly expressed in normal lung and kidney tissue and is expressed in lung adenocarcinomas
    FEBS Lett462, 129-134. PubMed  Europe PubMed DOI
  65. Moses,E.K., Freed,K.A., Higgins,J.R. and Brennecke,S.P.
    Alternative forms of a novel aspartyl protease gene are differentially expressed in human gestational tissues
    Mol Hum Reprod5, 983-989. PubMed  Europe PubMed DOI
  66. [YEAR:26-11-1999]Schauer-Vukasinovic,V., Bur,D., Kling,D., Gruninger,F. and Giller,T.
    Human napsin A: expression, immunochemical detection, and tissue localization
    FEBS Lett462, 135-139. PubMed  Europe PubMed DOI
  67. 1998
  68. [YEAR:11-12-1998]Tatnell,P.J., Powell,D.J., Hill,J., Smith,T.S., Tew,D.G. and Kay,J.
    Napsins: new human aspartic proteinases. Distinction between two closely related genes
    FEBS Lett441, 43-48. PubMed  Europe PubMed DOI
  69. 1997
  70. Gomes,R.A., Juliano,L., Chagas,J.R. and Hial,V.
    Characterization of kininogenase activity of an acidic proteinase isolated from human kidney
    Can J Physiol Pharmacol75, 757-761. PubMed  Europe PubMed DOI
  71. Mori,K., Ogawa,Y., Tamura,N., Ebihara,K., Aoki,T., Muro,S., Ozaki,S., Tanaka,I., Tashiro,K. and Nakao,K.
    Molecular cloning of a novel mouse aspartic protease-like protein that is expressed abundantly in the kidney
    FEBS Lett401, 218-222. PubMed  Europe PubMed DOI