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Literature for peptidase A01.043: histoaspartic peptidase (Plasmodium falciparum)

Summary Alignment Sequences Sequence features Distribution Structure Literature Substrates

(Topics flags: S Structure, K Knockout, I Inhibitor, E Expression, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2020
  1. Asua,V., Conrad,M.D., Aydemir,O., Duvalsaint,M., Legac,J., Duarte,E., Tumwebaze,P., Chin,D.M., Cooper,R.A., Yeka,A., Kamya,M.R., Dorsey,G., Nsobya,S.L., Bailey,J. and Rosenthal,P.J.
    Changing Prevalence of Potential Mediators of Aminoquinoline, Antifolate, and Artemisinin Resistance Across Uganda
    J Infect Dis PubMed  Europe PubMed DOI  I
    2. 2019
  2. Thillainayagam,M., Ramaiah,S. and Anbarasu,A.
    Computational investigation of novel benzene sulfonamide substituted pyrazole-pyrazoline analogues as potent inhibitors of Plasmodium falciparum histoaspartic protease
    J Biomol Struct Dyn1-19. PubMed  Europe PubMed DOI  I
    3. 2016
  3. Ponsuwanna,P., Kochakarn,T., Bunditvorapoom,D., Kumpornsin,K., Otto,T.D., Ridenour,C., Chotivanich,K., Wilairat,P., White,N.J., Miotto,O. and Chookajorn,T.
    Comparative genome-wide analysis and evolutionary history of haemoglobin-processing and haem detoxification enzymes in malarial parasites
    Malar J15, 51-51. PubMed  Europe PubMed DOI
    4. 2015
  4. McGillewie,L. and Soliman,M.E.
    Flap flexibility amongst plasmepsins I, II, III, IV, and V: sequence, structural, and molecular dynamics analyses
    Proteins83, 1693-1705. PubMed  Europe PubMed DOI
    5. 2013
  5. Chugh,M., Sundararaman,V., Kumar,S., Reddy,V.S., Siddiqui,W.A., Stuart,K.D. and Malhotra,P.
    Protein complex directs hemoglobin-to-hemozoin formation in Plasmodium falciparum
    Proc Natl Acad Sci U S A110, 5392-5397. PubMed  Europe PubMed DOI
    6. 2012
  6. Berry,C. and Goldberg,D.E.
    Histo-aspartic proteinase
    [ISSN:978-0-12-407744-7]3, 105-108. DOI
  7. Bhaumik,P., Gustchina,A. and Wlodawer,A.
    Structural studies of vacuolar plasmepsins
    Biochim Biophys Acta1824, 207-223. PubMed  Europe PubMed DOI  S
  8. Mahapatra,R.K., Behera,N. and Naik,P.K.
    Molecular modeling and prediction of binding mode and relative binding affinity of Art-Qui-OH with P. falciparum histo-aspartic protease (HAP)
    Bioinformation8, 827-833. PubMed  Europe PubMed DOI  I
    9. 2011
  9. Bhaumik,P., Xiao,H., Hidaka,K., Gustchina,A., Kiso,Y., Yada,R.Y. and Wlodawer,A.
    Structural insights into the activation and inhibition of histo-aspartic protease from Plasmodium falciparum
    Biochemistry50, 8862-8879. PubMed  Europe PubMed DOI  S
  10. Gil,L., Valiente,P.A., Pascutti,P.G. and Pons,T.
    Computational perspectives into plasmepsins structure-function relationship: implications to inhibitors design
    J Trop Med2011, 657483-657483. PubMed  Europe PubMed DOI  V
    11. 2010
  11. Xiao,H., Briere,L.A., Dunn,S.D. and Yada,R.Y.
    Characterization of the monomer-dimer equilibrium of recombinant histo-aspartic protease from Plasmodium falciparum
    Mol Biochem Parasitol173, 17-24. PubMed  Europe PubMed DOI
    12. 2009
  12. Bhaumik,P., Xiao,H., Parr,C.L., Kiso,Y., Gustchina,A., Yada,R.Y. and Wlodawer,A.
    Crystal structures of the histo-aspartic protease (HAP) from Plasmodium falciparum
    J Mol Biol388, 520-540. PubMed  Europe PubMed DOI  S  I
    13. 2008
  13. Parr,C.L., Tanaka,T., Xiao,H. and Yada,R.Y.
    The catalytic significance of the proposed active site residues in Plasmodium falciparum histoaspartic protease
    FEBS J275, 1698-1707. PubMed  Europe PubMed DOI
  14. Popov,M.E., Sten'gach,M.A. and Andreeva,N.S.
    Modeling of substrate and inhibitory complexes of histidine-aspartic protease
    Russ J Bioorganic Chem34, 380-386. DOI
  15. Popov,M.E., Sten'gach,M.A. and Andreeva,N.S.
    [Modeling of substrate and inhibitory complexes of histidine-aspartic protease]
    Bioorg Khim34, 422-429. PubMed  Europe PubMed
    16. 2007
  16. Bonilla,J.A., Bonilla,T.D., Yowell,C.A., Fujioka,H. and Dame,J.B.
    Critical roles for the digestive vacuole plasmepsins of Plasmodium falciparum in vacuolar function
    Mol Microbiol65, 64-75. PubMed  Europe PubMed DOI  K
  17. Bonilla,J.A., Moura,P.A., Bonilla,T.D., Yowell,C.A., Fidock,D.A. and Dame,J.B.
    Effects on growth, hemoglobin metabolism and paralogous gene expression resulting from disruption of genes encoding the digestive vacuole plasmepsins of Plasmodium falciparum
    Int J Parasitol37, 317-327. PubMed  Europe PubMed DOI  K
    18. 2006
  18. [YEAR:3-4-2006]Xiao,H., Sinkovits,A.F., Bryksa,B.C., Ogawa,M. and Yada,R.Y.
    Recombinant expression and partial characterization of an active soluble histo-aspartic protease from Plasmodium falciparum
    Protein Expr Purif49, 88-94. PubMed  Europe PubMed DOI  E
    19. 2005
  19. [YEAR:28-10-2005]Liu,J., Gluzman,I.Y., Drew,M.E. and Goldberg,D.E.
    The role of Plasmodium falciparum food vacuole plasmepsins
    J Biol Chem280, 1432-1437. PubMed  Europe PubMed DOI
  20. Valbuena,J., Vera,R., Puentes,A., Ocampo,M., Garcia,J., Curtidor,H., Lopez,R., Rodriguez,L., Rosas,J., Cortes,J., Forero,M., Pinto,M. and Patarroyo,M.E.
    P. falciparum pro-histoaspartic protease (proHAP) protein peptides bind specifically to erythrocytes and inhibit the invasion process in vitro
    Biol Chem386, 361-367. PubMed  Europe PubMed DOI
    21. 2004
  21. [YEAR:15-5-2004]Andreeva,N., Bogdanovich,P., Kashparov,I., Popov,M. and Stengach,M.
    Is histoaspartic protease a serine protease with a pepsin-like fold?
    Proteins55, 705-710. PubMed  Europe PubMed DOI
  22. Berry,C. and Goldberg,D.E.
    Plasmepsins
    [ISSN:0-12-079610-4]2, 70-73.  V
  23. [YEAR:23-11-2004]Bjelic,S. and Aqvist,J.
    Computational prediction of structure, substrate binding mode, mechanism, and rate for a malaria protease with a novel type of active site
    Biochemistry43, 14521-14528. PubMed  Europe PubMed DOI
  24. [YEAR:24-12-2004]Omara-Opyene,A.L., Moura,P.A., Sulsona,C.R., Bonilla,J.A., Yowell,C.A., Fujioka,H., Fidock,D.A. and Dame,J.B.
    Genetic disruption of the Plasmodium falciparum digestive vacuole plasmepsins demonstrates their functional redundancy
    J Biol Chem279, 54088-54096. PubMed  Europe PubMed DOI
    25. 2003
  25. Banerjee,R., Francis,S.E. and Goldberg,D.E.
    Food vacuole plasmepsins are processed at a conserved site by an acidic convertase activity in Plasmodium falciparum
    Mol Biochem Parasitol129, 157-165. PubMed  Europe PubMed DOI
  26. [YEAR:22-7-2003]Nezami,A., Kimura,T., Hidaka,K., Kiso,A., Liu,J., Kiso,Y., Goldberg,D.E. and Freire,E.
    High-affinity inhibition of a family of Plasmodium falciparum proteases by a designed adaptive inhibitor
    Biochemistry42, 8459-8464. PubMed  Europe PubMed DOI  I
    27. 2002
  27. [YEAR:22-1-2002]Banerjee,R., Liu,J., Beatty,W., Pelosof,L., Klemba,M. and Goldberg,D.E.
    Four plasmepsins are active in the Plasmodium falciparum food vacuole, including a protease with an active-site histidine
    Proc Natl Acad Sci U S A99, 990-995. PubMed  Europe PubMed DOI
    28. 1999
  28. [YEAR:26-3-1999]Berry,C., Humphreys,M.J., Matharu,P., Granger,R., Horrocks,P., Moon,R.P., Certa,U., Ridley,R.G., Bur,D. and Kay,J.
    A distinct member of the aspartic proteinase gene family from the human malaria parasite Plasmodium falciparum
    FEBS Lett447, 149-154. PubMed  Europe PubMed DOI

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