Literature for peptidase A01.014: candidapepsin SAP1
(Topics flags: S Structure, P Specificity, I Inhibitor, E Expression, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)
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Rapala-Kozik,M., Bochenska,O., Zajac,D., Karkowska-Kuleta,J., Gogol,M., Zawrotniak,M. and Kozik,A.
Extracellular proteinases of Candida species pathogenic yeasts
Mol Oral Microbiol33, 113-124. PubMed Europe PubMed DOI -
Gogol,M., Ostrowska,D., Klaga,K., Bochenska,O., Wolak,N., Aoki,W., Ueda,M., Kozik,A. and Rapala-Kozik,M.
Inactivation of alpha1-proteinase inhibitor by Candida albicans aspartic proteases favors the epithelial and endothelial cell colonization in the presence of neutrophil extracellular traps
Acta Biochim Pol63, 167-175. PubMed Europe PubMed DOI -
Cadicamo,C.D., Mortier,J., Wolber,G., Hell,M., Heinrich,I.E., Michel,D., Semlin,L., Berger,U., Korting,H.C., Holtje,H.D., Koksch,B. and Borelli,C.
Design, synthesis, inhibition studies, and molecular modeling of pepstatin analogues addressing different secreted aspartic proteinases of Candida albicans
Biochem Pharmacol85, 881-887. PubMed Europe PubMed DOI I -
Santos,A.L. and Braga-Silva,L.A.
Aspartic protease inhibitors: effective drugs against the human fungal pathogen Candida albicans
Mini Rev Med Chem13, 155-162. PubMed Europe PubMed -
Monod,M., Staib,P. and Borelli,C.
Candidapepsin
[ISSN:978-0-12-407744-7]3, 159-166. DOI -
Staniszewska,M., Bondaryk,M., Siennicka,K., Pilat,J., Schaller,M. and Kurzatkowski,W.
Role of aspartic proteinases in Candida albicans virulence. Part I. Substrate specificity of aspartic proteinases and Candida albicans
Postepy Mikrobiol51, 127-135. V -
Staniszewska,M., Bondaryk,M., Siennicka,K., Pilat,J., Schaller,M. and Kurzatkowski,W.
Role of aspartic proteinases in Candida albicans virulence. Part II: Expression of SAP1-10 aspartic proteinase during Candida albicans infections in vivo
Postepy Mikrobiol51, 137-142. -
Aoki,W., Kitahara,N., Miura,N., Morisaka,H., Yamamoto,Y., Kuroda,K. and Ueda,M.
Comprehensive characterization of secreted aspartic proteases encoded by a virulence gene family in Candida albicans
J Biochem150, 431-438. PubMed Europe PubMed DOI P -
Braga-Silva,L.A. and Santos,A.L.S.
Aspartic protease inhibitors as potential anti-Candida albicans drugs: impacts on fungal biology, virulence and pathogenesis
Curr Med Chem18, 2401-2419. PubMed Europe PubMed DOI I -
Buchold,C., Hemberger,Y., Heindl,C., Welker,A., Degel,B., Pfeuffer,T., Staib,P., Schneider,S., Rosenthal,P.J., Gut,J., Morschhauser,J., Bringmann,G. and Schirmeister,T.
New cis-configured aziridine-2-carboxylates as aspartic acid protease inhibitors
ChemMedChem6, 141-152. PubMed Europe PubMed DOI I -
Correia,A., Lermann,U., Teixeira,L., Cerca,F., Botelho,S., Gil Da Costa,R.M., Sampaio,P., Gartner,F., Morschhauser,J., Vilanova,M. and Pais,C.
Limited role of secreted aspartyl proteinases Sap1 to Sap6 in Candida albicans virulence and host immune response in murine hematogenously disseminated candidiasis
Infect Immun78, 4839-4849. PubMed Europe PubMed DOI -
Pietrella,D., Rachini,A., Pandey,N., Schild,L., Netea,M., Bistoni,F., Hube,B. and Vecchiarelli,A.
The Inflammatory response induced by aspartic proteases of Candida albicans is independent of proteolytic activity
Infect Immun78, 4754-4762. PubMed Europe PubMed DOI -
Gropp,K., Schild,L., Schindler,S., Hube,B., Zipfel,P.F. and Skerka,C.
The yeast Candida albicans evades human complement attack by secretion of aspartic proteases
Mol Immunol47, 465-475. PubMed Europe PubMed DOI -
Parra-Ortega,B., Cruz-Torres,H., Villa-Tanaca,L. and Hernandez-Rodriguez,C.
Phylogeny and evolution of the aspartyl protease family from clinically relevant Candida species
Mem Inst Oswaldo Cruz104, 505-512. PubMed Europe PubMed -
Borelli,C., Ruge,E., Lee,J.H., Schaller,M., Vogelsang,A., Monod,M., Korting,H.C., Huber,R. and Maskos,K.
X-ray structures of Sap1 and Sap5: structural comparison of the secreted aspartic proteinases from Candida albicans
Proteins72, 1308-1319. PubMed Europe PubMed DOI S -
Lermann,U. and Morschhauser,J.
Secreted aspartic proteases are not required for invasion of reconstituted human epithelia by Candida albicans
Microbiology (Reading)154, 3281-3295. PubMed Europe PubMed DOI -
Naglik,J.R., Moyes,D., Makwana,J., Kanzaria,P., Tsichlaki,E., Weindl,G., Tappuni,A.R., Rodgers,C.A., Woodman,A.J., Challacombe,S.J., Schaller,M. and Hube,B.
Quantitative expression of the Candida albicans secreted aspartyl proteinase gene family in human oral and vaginal candidiasis
Microbiology (Reading)154, 3266-3280. PubMed Europe PubMed DOI -
Odds,F.C.
Secreted proteinases and Candida albicans virulence
Microbiology (Reading)154, 3245-3246. PubMed Europe PubMed DOI -
Staib,P., Lermann,U., Blass-Warmuth,J., Degel,B., Wurzner,R., Monod,M., Schirmeister,T. and Morschhauser,J.
Tetracycline-inducible expression of individual secreted aspartic proteases in Candida albicans allows isoenzyme-specific inhibitor screening
Antimicrob Agents Chemother52, 146-156. PubMed Europe PubMed DOI -
Majer,F., Pavlickova,L., Majer,P., Hradilek,M., Dolejsi,E., Hruskova-Heidingsfeldova,O. and Pichova,I.
Structure-based specificity mapping of secreted aspartic proteases of Candida parapsilosis, Candida albicans, and Candida tropicalis using peptidomimetic inhibitors and homology modeling
Biol Chem387, 1247-1254. PubMed Europe PubMed DOI P I -
Foundling,S.I.
Candidapepsin
[ISSN:0-12-079610-4]2, 115-120. V -
[YEAR:21-3-2003]Backman,D. and Danielson,U.H.
Kinetic and mechanistic analysis of the association and dissociation of inhibitors interacting with secreted aspartic acid proteases 1 and 2 from Candida albicans
Biochim Biophys Acta1646, 184-195. PubMed Europe PubMed DOI I -
Korting,H.C., Hube,B., Oberbauer,S., Januschke,E., Hamm,G., Albrecht,A., Borelli,C. and Schaller,M.
Reduced expression of the hyphal-independent Candida albicans proteinase genes SAP1 and SAP3 in the efg1 mutant is associated with attenuated virulence during infection of oral epithelium
J Med Microbiol52, 623-632. PubMed Europe PubMed DOI -
Naglik,J.R., Challacombe,S.J. and Hube,B.
Candida albicans secreted aspartyl proteinases in virulence and pathogenesis
Microbiol Mol Biol Rev67, 400-428. PubMed Europe PubMed DOI -
Schaller,M., Bein,M., Korting,H.C., Baur,S., Hamm,G., Monod,M., Beinhauer,S. and Hube,B.
The secreted aspartyl proteinases Sap1 and Sap2 cause tissue damage in an in vitro model of vaginal candidiasis based on reconstituted human vaginal epithelium
Infect Immun71, 3227-3234. PubMed Europe PubMed DOI I -
Felk,A., Kretschmar,M., Albrecht,A., Schaller,M., Beinhauer,S., Nichterlein,T., Sanglard,D., Korting,H.C., Schafer,W. and Hube,B.
Candida albicans hyphal formation and the expression of the Efg1-regulated proteinases Sap4 to Sap6 are required for the invasion of parenchymal organs
Infect Immun70, 3689-3700. PubMed Europe PubMed DOI -
Kretschmar,M., Felk,A., Staib,P., Schaller,M., Hess,D., Callapina,M., Morschhauser,J., Schafer,W., Korting,H.C., Hof,H., Hube,B. and Nichterlein,T.
Individual acid aspartic proteinases (Saps) 1-6 of Candida albicans are not essential for invasion and colonization of the gastrointestinal tract in mice
Microb Pathog32, 61-70. PubMed Europe PubMed DOI -
De Bernardis,F., Sullivan,P.A. and Cassone,A.
Aspartyl proteinases of Candida albicans and their role in pathogenicity
Med Mycol39, 303-313. PubMed Europe PubMed -
Hube,B. and Naglik,J.
Candida albicans proteinases: resolving the mystery of a gene family
Microbiology (Reading, Engl )147, 1997-2005. PubMed Europe PubMed -
Pichova,I., Pavlickova,L., Dostal,J., Dolejsi,E., Hruskova-Heidingsfeldova,O., Weber,J., Ruml,T. and Soucek,M.
Secreted aspartic proteases of Candida albicans, Candida tropicalis, Candida parapsilosis and Candida lusitaniae. Inhibition with peptidomimetic inhibitors
Eur J Biochem268, 2669-2677. PubMed Europe PubMed DOI I -
Schaller,M., Januschke,E., Schackert,C., Woerle,B. and Korting,H.C.
Different isoforms of secreted aspartyl proteinases (Sap) are expressed by Candida albicans during oral and cutaneous candidosis in vivo
J Med Microbiol50, 743-747. PubMed Europe PubMed -
Stewart,K. and Abad-Zapatero,C.
Candida proteases and their inhibition: prospects for antifungal therapy
Curr Med Chem8, 941-948. PubMed Europe PubMed I -
Beggah,S., Lechenne,B., Reichard,U., Foundling,S. and Monod,M.
Intra- and intermolecular events direct the propeptide-mediated maturation of the Candida albicans secreted aspartic proteinase Sap1p
Microbiology (Reading, Engl )146, 2765-2773. PubMed Europe PubMed -
[YEAR:14-7-2000]Koelsch,G., Tang,J., Loy,J.A., Monod,M., Jackson,K., Foundling,S.I. and Lin,X.L.
Enzymic characteristics of secreted aspartic proteases of Candida albicans
Biochim Biophys Acta1480, 117-131. PubMed Europe PubMed DOI -
Schaller,M., Schackert,C., Korting,H.C., Januschke,E. and Hube,B.
Invasion of Candida albicans correlates with expression of secreted aspartic proteinases during experimental infection of human epidermis
J Invest Dermatol114, 712-717. PubMed Europe PubMed DOI -
[YEAR:23-5-2000]Staib,P., Kretschmar,M., Nichterlein,T., Hof,H. and Morschhauser,J.
Differential activation of a Candida albicans virulence gene family during infection
Proc Natl Acad Sci U S A97, 6102-6107. PubMed Europe PubMed DOI -
Stehr,F., Felk,A., Kretschmar,M., Schaller,M., Schafer,W. and Hube,B.
[Extracellular hydrolytic enzymes and their relevance during Candida albicans infections]
Mycoses43 Suppl 2, 17-21. PubMed Europe PubMed -
Borg-von Zepelin,M., Meyer,I., Thomssen,R., Wurzner,R., Sanglard,D., Telenti,A. and Monod,M.
HIV-protease inhibitors reduce cell adherence of Candida albicans strains by inhibition of yeast secreted aspartic proteases
J Invest Dermatol113, 747-751. PubMed Europe PubMed DOI I -
Gruber,A., Berlit,J., Speth,C., Lass-Florl,C., Kofler,G., Nagl,M., Borg-von Zepelin,M., Dierich,M.P. and Wurzner,R.
Dissimilar attenuation of Candida albicans virulence properties by human immunodeficiency virus type 1 protease inhibitors
Immunobiology201, 133-144. PubMed Europe PubMed DOI I -
Korting,H.C., Schaller,M., Eder,G., Hamm,G., Bohmer,U. and Hube,B.
Effects of the human immunodeficiency virus (HIV) proteinase inhibitors saquinavir and indinavir on in vitro activities of secreted aspartyl proteinases of Candida albicans isolates from HIV-Infected patients
Antimicrobial Agents Chemother43, 2038-2042. PubMed Europe PubMed I -
Kretschmar,M., Hube,B., Bertsch,T., Sanglard,D., Merker,R., Schroder,M., Hof,H. and Nichterlein,T.
Germ tubes and proteinase activity contribute to virulence of Candida albicans in murine peritonitis
Infect Immun67, 6637-6642. PubMed Europe PubMed -
Monod,M., Borg-von Zepelin,M., Telenti,A. and Sanglard,D.
The inhibition of Candida-albicans-secreted aspartic proteases by three different HIV protease inhibitors
Dermatology198, 412-414. PubMed Europe PubMed I -
Na,B.K. and Song,C.Y.
Use of monoclonal antibody in diagnosis of candidiasis caused by Candida albicans: Detection of circulating aspartyl proteinase antigen
Clin Diagn Lab Immunol6, 924-929. PubMed Europe PubMed -
Schaller,M., Korting,H.C., Schafer,W., Bastert,J., Chen,W. and Hube,B.
Secreted aspartic proteinase (Sap) activity contributes to tissue damage in a model of human oral candidosis
Mol Microbiol34, 169-180. PubMed Europe PubMed DOI -
Borg-von Zepelin,M., Beggah,S., Boggian,K., Sanglard,D. and Monod,M.
The expression of the secreted aspartyl proteinases Sap4 to Sap6 from Candida albicans in murine macrophages
Mol Microbiol28, 543-554. PubMed Europe PubMed DOI E -
Monod,M., Hube,B., Hess,D. and Sanglard,D.
Differential regulation of SAP8 and SAP9, which encode two new members of the secreted aspartic proteinase family in Candida albicans
Microbiology (Reading, Engl )144, 2731-2737. PubMed Europe PubMed -
Pichova,I., Brozkova,K., Pavlickova,L., Fusek,M., Krizova,I., Ruml,T. and Soucek,M.
Development and testing of inhibitors of Candida aspartic proteinases
Adv Exp Med Biol436, 329-333. PubMed Europe PubMed -
Hube,B., Sanglard,D., Odds,F.C., Hess,D., Monod,M., Schafer,W., Brown,A.J. and Gow,N.A.
Disruption of each of the secreted aspartyl proteinase genes SAP1, SAP2, and SAP3 of Candida albicans attenuates virulence
Infect Immun65, 3529-3538. PubMed Europe PubMed -
Smolenski,G., Sullivan,P.A., Cutfield,S.M. and Cutfield,J.F.
Analysis of secreted aspartic proteinases from Candida albicans: purification and characterization of individual Sap1, Sap2 and Sap3 isoenzymes
Microbiology (Reading, Engl )143, 349-356. PubMed Europe PubMed -
Hoegl,L., Ollert,M. and Korting,H.C.
The role of Candida albicans secreted aspartic proteinase in the development of candidoses
J Mol Med74, 135-142. PubMed Europe PubMed DOI -
White,T.C., Andrews,L.E., Maltby,D. and Agabian,N.
The "universal" leucine codon CTG in the secreted aspartyl proteinase 1 (SAP1) gene of Candida albicans encodes a serine in vivo
J Bacteriol177, 2953-2955. PubMed Europe PubMed -
Fusek,M., Smith,E.A., Monod,M., Dunn,B.M. and Foundling,S.I.
Extracellular aspartic proteinases from Candida albicans, Candida tropicalis, and Candida parapsilosis yeasts differ substantially in their specificities
Biochemistry33, 9791-9799. PubMed Europe PubMed -
Hube,B., Monod,M., Schofield,D.A., Brown,A.J. and Gow,N.A.
Expression of seven members of the gene family encoding secretory aspartyl proteinases in Candida albicans
Mol Microbiol14, 87-99. PubMed Europe PubMed DOI -
Miyasaki,S.H., White,T.C. and Agabian,N.
A fourth secreted aspartyl proteinase gene (SAP4) and a CARE2 repetitive element are located upstream of the SAP1 gene in Candida albicans
J Bacteriol176, 1702-1710. PubMed Europe PubMed -
Monod,M., Togni,G., Hube,B. and Sanglard,D.
Multiplicity of genes encoding secreted aspartic proteinases in Candida species
Mol Microbiol13, 357-368. PubMed Europe PubMed DOI -
Odds,F.C.
Pathogenesis of Candida infections
J Am Acad Dermatol31, S2-S5. PubMed Europe PubMed -
Tsushima,H., Mine,H., Kawakami,Y., Hyodoh,F. and Ueki,A.
Candida albicans aspartic proteinase cleaves and inactivates human epidermal cysteine proteinase inhibitor, cystatin A
Microbiology (Reading, Engl )140, 167-171. PubMed Europe PubMed -
Ogrydziak,D.M.
Yeast extracellular proteases
Crit Rev Biotechnol13, 1-55. PubMed Europe PubMed DOI -
White,T.C., Miyasaki,S.H. and Agabian,N.
Three distinct secreted aspartyl proteinases in Candida albicans
J Bacteriol175, 6126-6133. PubMed Europe PubMed -
Capobianco,J.O., Lerner,C.G. and Goldman,R.C.
Application of a fluorogenic substrate in the assay of proteolytic activity and in the discovery of a potent inhibitor of Candida albicans aspartic proteinase
Anal Biochem204, 96-102. PubMed Europe PubMed DOI I -
Mukai,H., Takeda,O., Asada,K., Kato,I., Murayama,S.Y. and Yamaguchi,H.
cDNA cloning of an aspartic proteinase secreted by Candida albicans
Microbiol Immunol36, 1207-1216. PubMed Europe PubMed -
Mukai,H., Takeda,O., Asada,K., Kato,I., Murayama,S.Y. and Yamaguchi,H.
cDNA cloning of an aspartic proteinase secreted by Candida albicans
Microbiol Immunol36, 105-111. -
Sono,E., Masuda,T., Takesako,K., Kato,I., Uchida,K., Murayama,S.Y. and Yamaguchi,H.
Comparison of secretory acid proteinases from Candida tropicalis, C. parapsilosis and C. albicans
Microbiol Immunol36, 1099-1104. PubMed Europe PubMed -
Ganesan,K., Banerjee,A. and Datta,A.
Molecular cloning of the secretory acid proteinase gene from Candida albicans and its use as a species-specific probe
Infect Immun59, 2972-2977. PubMed Europe PubMed -
Hube,B., Turver,C.J., Odds,F.C., Eiffert,H., Boulnois,G.J., Kochel,H. and Ruchel,R.
Sequence of the Candida albicans gene encoding the secretory aspartate proteinase
Med Mycol29, 129-132. DOI -
Hube,B., Turver,C.J., Odds,F.C., Eiffert,H., Boulnois,G.J., Kochel,H. and Ruchel,R.
Sequence of the Candida albicans gene encoding the secretory aspartate proteinase
J Med Vet Mycol29, 129-132. PubMed Europe PubMed -
Ross,I.K., De Bernardis,F., Emerson,G.W., Cassone,A. and Sullivan,P.A.
The secreted aspartate proteinase of Candida albicans: physiology of secretion and virulence of a proteinase-deficient mutant
J Gen Microbiol136, 687-694. PubMed Europe PubMed -
Lott,T.J., Page,L.S., Boiron,P., Benson,J. and Reiss,E.
Nucleotide sequence of the Candida albicans aspartyl proteinase gene
Nucleic Acids Res17, 1779-1779. PubMed Europe PubMed -
Borg,M. and Ruchel,R.
Expression of extracellular acid proteinase by proteolytic Candida spp. during experimental infection of oral mucosa
Infect Immun56, 626-631. PubMed Europe PubMed -
Ruchel,R.
Cleavage of immunoglobulins by pathogenic yeasts of the genus Candida
Microbiol Sci3, 316-319. PubMed Europe PubMed -
Negi,M., Tsuboi,R., Matsui,T. and Ogawa,H.
Isolation and characterization of proteinase from Candida albicans: substrate specificity
J Invest Dermatol83, 32-36. PubMed Europe PubMed P -
Ruchel,R.
On the renin-like activity of Candida proteinases and activation of blood coagulation in vitro
Zentralbl Bakteriol Mikrobiol Hyg A255, 368-379. PubMed Europe PubMed -
Ruchel,R.
Properties of a purified proteinase from the yeast Candida albicans
Biochim Biophys Acta659, 99-113. PubMed Europe PubMed -
Remold,H., Fasold,H. and Staib,F.
Purification and characterization of a proteolytic enzyme from Candida albicans
Biochim Biophys Acta167, 399-406. PubMed Europe PubMed
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