Literature for peptidase C13.004: legumain, animal-type

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

(References are filtered for relevance to Structure. To remove the filter click here. See explanation.)

2017

Zhang,Z., Obianyo,O., Dall,E., Du,Y., Fu,H., Liu,X., Kang,S.S., Song,M., Yu,S.P., Cabrele,C., Schubert,M., Li,X., Wang,J.Z., Brandstetter,H. and Ye,K.
Inhibition of delta-secretase improves cognitive functions in mouse models of Alzheimer's disease
Nat Commun8, 14740-14740. PubMed Europe PubMed DOI S I

2015

Dall,E., Fegg,J.C., Briza,P. and Brandstetter,H.
Structure and mechanism of an aspartimide-dependent peptide ligase in human legumain
Angew Chem Int Ed Engl54, 2917-2921. PubMed Europe PubMed DOI S

2014

Zhao,L., Hua,T., Crowley,C., Ru,H., Ni,X., Shaw,N., Jiao,L., Ding,W., Qu,L., Hung,L.W., Huang,W., Liu,L., Ye,K., Ouyang,S., Cheng,G. and Liu,Z.J.
Structural analysis of asparaginyl endopeptidase reveals the activation mechanism and a reversible intermediate maturation stage
Cell Res24, 344-358. PubMed Europe PubMed DOI S

2013

Dall,E. and Brandstetter,H.
Mechanistic and structural studies on legumain explain its zymogenicity, distinct activation pathways, and regulation
Proc Natl Acad Sci U S A110, 10940-10945. PubMed Europe PubMed DOI S