Literature for peptidase S09.003: dipeptidyl-peptidase IV (eukaryote)

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

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    2025
  1. Shen,C., Oh,H.R., Park,Y.R., Oh,S. and Park,J.H.
    Soluble DPP4 promotes hepatocyte lipid accumulation via SOX2-SCD1 signaling and counteracts DPP4 inhibition
    Biochem Biophys Res Commun756, 151521-151521. PubMed  Europe PubMed DOI  K
  2. 2024
  3. Nag,S., Mandal,S., Mukherjee,O., Majumdar,T., Mukhopadhyay,S. and Kundu,R.
    Vildagliptin inhibits high fat and fetuin-A mediated DPP-4 expression, intracellular lipid accumulation and improves insulin secretory defects in pancreatic beta cells
    Biochim Biophys Acta Mol Basis Dis1870, 167047-167047. PubMed  Europe PubMed DOI  K  I
  4. 2021
  5. Hu,X., Chen,S., Xie,C., Li,Z., Wu,Z. and You,Z.
    DPP4 gene silencing inhibits proliferation and epithelial-mesenchymal transition of papillary thyroid carcinoma cells through suppression of the MAPK pathway
    J Endocrinol Invest PubMed  Europe PubMed DOI  K
  6. 2020
  7. Du,J., Fu,L., Ji,F., Wang,C., Liu,S. and Qiu,X.
    FosB recruits KAT5 to potentiate the growth and metastasis of papillary thyroid cancer in a DPP4-dependent manner
    Life Sci259, 118374-118374. PubMed  Europe PubMed DOI  K
  8. 2019
  9. Zhao,X., Zhang,K., Daniel,P., Wisbrun,N., Fuchs,H. and Fan,H.
    Delayed allogeneic skin graft rejection in CD26-deficient mice
    Cell Mol Immunol16, 557-567. PubMed  Europe PubMed DOI  K
  10. 2018
  11. Svarcbahs,R., Julku,U.H., Norrbacka,S. and Myohanen,T.T.
    Removal of prolyl oligopeptidase reduces alpha-synuclein toxicity in cells and in vivo
    Sci Rep8, 1552-1552. PubMed  Europe PubMed DOI  K
  12. 2014
  13. Ku,H.C. and Su,M.J.
    DPP4 Deficiency preserved cardiac function in abdominal aortic banding rats
    PLoS ONE9, e85634-e85634. PubMed  Europe PubMed DOI  K
  14. 2013
  15. Ben-Shlomo,S., Zvibel,I., Rabinowich,L., Goldiner,I., Shlomai,A., Santo,E.M., Halpern,Z., Oren,R. and Fishman,S.
    Dipeptidyl peptidase 4-deficient rats have improved bile secretory function in high fat diet-induced steatosis
    Dig Dis Sci58, 172-178. PubMed  Europe PubMed DOI  K
  16. 2012
  17. Detel,D., Pugel,E.P., Pucar,L.B., Buljevic,S. and Varljen,J.
    Development and resolution of colitis in mice with target deletion of dipeptidyl peptidase IV
    Exp Physiol97, 486-496. PubMed  Europe PubMed DOI  K
  18. 2011
  19. Kidd,S., Bueso-Ramos,C., Jagan,S., Paganessi,L.A., Boggio,L.N., Fung,H.C., Gregory,S.A. and Christopherson,K.W.
    In Vivo expansion of the megakaryocyte progenitor cell population in adult CD26-deficient mice
    Exp Hematol39, 580-590. PubMed  Europe PubMed DOI  K
  20. Ku,H.C., Chen,W.P. and Su,M.J.
    DPP4 deficiency preserves cardiac function via GLP-1 signaling in rats subjected to myocardial ischemia/reperfusion
    Naunyn Schmiedebergs Arch Pharmacol384, 197-207. PubMed  Europe PubMed DOI  K
  21. 2010
  22. Sauve,M., Ban,K., Momen,M.A., Zhou,Y.Q., Henkelman,R.M., Husain,M. and Drucker,D.J.
    Genetic deletion or pharmacological inhibition of dipeptidyl peptidase-4 improves cardiovascular outcomes after myocardial infarction in mice
    Diabetes59, 1063-1073. PubMed  Europe PubMed DOI  K  I
  23. 2009
  24. Kirino,Y., Sato,Y., Kamimoto,T., Kawazoe,K., Minakuchi,K. and Nakahori,Y.
    Interrelationship of dipeptidyl peptidase IV (DPP4) with the development of diabetes, dyslipidaemia and nephropathy: a streptozotocin-induced model using wild-type and DPP4-deficient rats
    J Endocrinol200, 53-61. PubMed  Europe PubMed DOI  K
  25. Klemann,C., Schade,J., Pabst,R., Leitner,S., Stiller,J., von Horsten,S. and Stephan,M.
    CD26/dipeptidyl peptidase 4-deficiency alters thymic emigration patterns and leukocyte subsets in F344-rats age-dependently
    Clin Exp Immunol155, 357-365. PubMed  Europe PubMed DOI  K
  26. 2003
  27. [YEAR:27-5-2003]Conarello,S.L., Li,Z., Ronan,J., Roy,R.S., Zhu,L., Jiang,G., Liu,F., Woods,J., Zycband,E., Moller,D.E., Thornberry,N.A. and Zhang,B.B.
    Mice lacking dipeptidyl peptidase IV are protected against obesity and insulin resistance
    Proc Natl Acad Sci U S A100, 6825-6830. PubMed  Europe PubMed DOI  K
  28. 2000
  29. [YEAR:6-6-2000]Marguet,D., Baggio,L., Kobayashi,T., Bernard,A.M., Pierres,M., Nielsen,P.F., Ribel,U., Watanabe,T., Drucker,D.J. and Wagtmann,N.
    Enhanced insulin secretion and improved glucose tolerance in mice lacking CD26
    Proc Natl Acad Sci U S A97, 6874-6879. PubMed  Europe PubMed DOI  K
  30. 1999
  31. Cheng,H.C., Abdel-Ghany,M., Zhang,S. and Pauli,B.U.
    Is the Fischer 344/CRJ rat a protein-knock-out model for dipeptidyl peptidase IV-mediated lung metastasis of breast cancer?
    Clin Exp Metastasis17, 609-615. PubMed  Europe PubMed DOI  K
  32. 1996
  33. Pederson,R.A., Kieffer,T.J., Pauly,R., Kofod,H., Kwong,J. and McIntosh,C.H.
    The enteroinsular axis in dipeptidyl peptidase IV-negative rats
    Metabolism45, 1335-1341. PubMed  Europe PubMed DOI  K
  34. 1992
  35. [YEAR:1-12-1992]Tsuji,E., Misumi,Y., Fujiwara,T., Takami,N., Ogata,S. and Ikehara,Y.
    An active-site mutation (Gly633 - >Arg) of dipeptidyl peptidase IV causes its retention and rapid degradation in the endoplasmic reticulum
    Biochemistry31, 11921-11927. PubMed  Europe PubMed DOI  K
  36. 1990
  37. [YEAR:5-2-1990]Tiruppathi,C., Ganapathy,V. and Leibach,F.H.
    Evidence for tripeptide-proton symport in renal brush border membrane vesicles. Studies in a novel rat strain with a genetic absence of dipeptidyl peptidase IV
    J Biol Chem265, 2048-2053. PubMed  Europe PubMed  K