Literature for peptidase C01.032: cathepsin L

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2024
1. Bestle,D., Bittel,L., Werner,A.D., Kamper,L., Dolnik,O., Krahling,V., Steinmetzer,T. and Bottcher-Friebertshauser,E.
   Novel proteolytic activation of Ebolavirus glycoprotein GP by TMPRSS2 and cathepsin L at an uncharted position can compensate for furin cleavage
   Virus Res347, 199430-199430. PubMed  Europe PubMed DOI  K
2. Zhang,K., Xu,R., Zheng,L., Zhang,H., Qian,Z., Li,C., Xue,M., He,Z., Ma,J., Li,Z., Chen,L., Ma,R. and Yao,B.
   Elevated N-glycosylated cathepsin L impairs oocyte function and contributes to oocyte senescence during reproductive aging
   Aging Celle14397-e14397. PubMed  Europe PubMed DOI  K
2022
3. Mondal,S., Chen,Y., Lockbaum,G.J., Sen,S., Chaudhuri,S., Reyes,A.C., Lee,J.M., Kaur,A.N., Sultana,N., Cameron,M.D., Shaffer,S.A., Schiffer,C.A., Fitzgerald,K.A. and Thompson,P.R.
   Dual Inhibitors of Main Protease (M(Pro)) and Cathepsin L as Potent Antivirals against SARS-CoV2
   J Am Chem Soc144, 21035-21045. PubMed  Europe PubMed DOI  K  I
2021
4. Zhao,M.M., Yang,W.L., Yang,F.Y., Zhang,L., Huang,W.J., Hou,W., Fan,C.F., Jin,R.H., Feng,Y.M., Wang,Y.C. and Yang,J.K.
   Cathepsin L plays a key role in SARS-CoV-2 infection in humans and humanized mice and is a promising target for new drug development
   Signal Transduct Target Ther6, 134-134. PubMed  Europe PubMed DOI  K
2020
5. Parigiani,M.A., Ketscher,A., Timme,S., Bronsert,P., Schlimpert,M., Kammerer,B., Jacquel,A., Chaintreuil,P. and Reinheckel,T.
   Conditional Gene Targeting Reveals Cell Type-Specific Roles of the Lysosomal Protease Cathepsin L in Mammary Tumor Progression
   Cancers (Basel)12, PubMed  Europe PubMed DOI  K
2016
6. Zhang,H., Zhang,L., Wei,L., Gao,X., Tang,L., Gong,W., Min,N., Zhang,L. and Yuan,Y.
   Knockdown of cathepsin L sensitizes ovarian cancer cells to chemotherapy
   Oncol Lett11, 4235-4239. PubMed  Europe PubMed DOI  K
2015
7. Brindle,N.R., Joyce,J.A., Rostker,F., Lawlor,E.R., Swigart-Brown,L., Evan,G., Hanahan,D. and Shchors,K.
   Deficiency for the cysteine protease cathepsin L impairs myc-induced tumorigenesis in a mouse model of pancreatic neuroendocrine cancer
   PLoS ONE10, e0120348- PubMed  Europe PubMed DOI  K
2014
8. Tholen,S., Biniossek,M.L., Gansz,M., Ahrens,T.D., Schlimpert,M., Kizhakkedathu,J.N., Reinheckel,T. and Schilling,O.
   Double deficiency of cathepsins B and L results in massive secretome alterations and suggests a degradative cathepsin-MMP axis
   Cell Mol Life Sci71, 899-916. PubMed  Europe PubMed DOI  K
2013
9. Tholen,S., Biniossek,M.L., Gansz,M., Gomez-Auli,A., Bengsch,F., Noel,A., Kizhakkedathu,J.N., Boerries,M., Busch,H., Reinheckel,T. and Schilling,O.
   Deletion of cysteine cathepsins B or L yields differential impacts on murine skin proteome and degradome
   Mol Cell Proteomics12, 611-625. PubMed  Europe PubMed DOI  K
2011
10. Sun,J., Sukhova,G.K., Zhang,J., Chen,H., Sjoberg,S., Libby,P., Xiang,M., Wang,J., Peters,C., Reinheckel,T. and Shi,G.P.
    Cathepsin L activity is essential to elastase perfusion-induced abdominal aortic aneurysms in mice
    Arterioscler Thromb Vasc Biol31, 2500-2508. PubMed  Europe PubMed DOI  K
11. Sun,M., Chen,M., Liu,Y., Fukuoka,M., Zhou,K., Li,G., Dawood,F., Gramolini,A. and Liu,P.P.
    Cathepsin-L contributes to cardiac repair and remodelling post-infarction
    Cardiovasc Res89, 374-383. PubMed  Europe PubMed DOI  K
12. Tholen,S., Biniossek,M.L., Gessler,A.L., Muller,S., Weisser,J., Kizhakkedathu,J.N., Reinheckel,T. and Schilling,O.
    Contribution of cathepsin L to secretome composition and cleavage pattern of mouse embryonic fibroblasts
    Biol Chem392, 961-971. PubMed  Europe PubMed DOI  K
2010
13. Dennemarker,J., Lohmuller,T., Muller,S., Aguilar,S.V., Tobin,D.J., Peters,C. and Reinheckel,T.
    Impaired turnover of autophagolysosomes in cathepsin L deficiency
    Biol Chem391, 913-922. PubMed  Europe PubMed DOI  K
14. Dennemarker,J., Lohmuller,T., Mayerle,J., Tacke,M., Lerch,M.M., Coussens,L.M., Peters,C. and Reinheckel,T.
    Deficiency for the cysteine protease cathepsin L promotes tumor progression in mouse epidermis
    Oncogene29, 1611-1621. PubMed  Europe PubMed DOI  K
15. Minokadeh,A., Funkelstein,L., Toneff,T., Hwang,S.R., Beinfeld,M., Reinheckel,T., Peters,C., Zadina,J. and Hook,V.
    Cathepsin L participates in dynorphin production in brain cortex, illustrated by protease gene knockout and expression
    Mol Cell Neurosci43, 98-107. PubMed  Europe PubMed DOI  K
16. Zeeuwen,P.L., van Vlijmen-Willems,I.M., Cheng,T., Rodijk-Olthuis,D., Hitomi,K., Hara-Nishimura,I., John,S., Smyth,N., Reinheckel,T., Hendriks,W.J. and Schalkwijk,J.
    The cystatin M/E-cathepsin L balance is essential for tissue homeostasis in epidermis, hair follicles, and cornea
    FASEB J24, 3744-3755. PubMed  Europe PubMed DOI  K
2009
17. Beinfeld,M.C., Funkelstein,L., Foulon,T., Cadel,S., Kitagawa,K., Toneff,T., Reinheckel,T., Peters,C. and Hook,V.
    Cathepsin L plays a major role in cholecystokinin production in mouse brain cortex and in pituitary AtT-20 cells: protease gene knockout and inhibitor studies
    Peptides30, 1882-1891. PubMed  Europe PubMed DOI  K  I
18. Luft,F.C.
    From furless to heartless - unraveling the diverse functions of cathepsin L
    J Mol Med (Berl)87, 225-227. PubMed  Europe PubMed DOI  K
2008
19. Funkelstein,L., Toneff,T., Hwang,S.R., Reinheckel,T., Peters,C. and Hook,V.
    Cathepsin L participates in the production of neuropeptide Y in secretory vesicles, demonstrated by protease gene knockout and expression
    J Neurochem106, 384-391. PubMed  Europe PubMed DOI  K
2007
20. Boudreau,F., Lussier,C.R., Mongrain,S., Darsigny,M., Drouin,J.L., Doyon,G., Suh,E.R., Beaulieu,J.F., Rivard,N. and Perreault,N.
    Loss of cathepsin L activity promotes claudin-1 overexpression and intestinal neoplasia
    FASEB J21, 3853-3865. PubMed  Europe PubMed DOI  K
21. Stahl,S., Reinders,Y., Asan,E., Mothes,W., Conzelmann,E., Sickmann,A. and Felbor,U.
    Proteomic analysis of cathepsin B- and L-deficient mouse brain lysosomes
    Biochim Biophys Acta1774, 1237-1246. PubMed  Europe PubMed DOI  K
22. Yang,M., Zhang,Y., Pan,J., Sun,J., Liu,J., Libby,P., Sukhova,G.K., Doria,A., Katunuma,N., Peroni,O.D., Guerre-Millo,M., Kahn,B.B., Clement,K. and Shi,G.P.
    Cathepsin L activity controls adipogenesis and glucose tolerance
    Nat Cell Biol9, 970-977. PubMed  Europe PubMed DOI  K  I
2006
23. Petermann,I., Mayer,C., Stypmann,J., Biniossek,M.L., Tobin,D.J., Engelen,M.A., Dandekar,T., Grune,T., Schild,L., Peters,C. and Reinheckel,T.
    Lysosomal, cytoskeletal, and metabolic alterations in cardiomyopathy of cathepsin L knockout mice
    FASEB J20, 1266-1268. PubMed  Europe PubMed DOI  K
24. Sevenich,L., Pennacchio,L.A., Peters,C. and Reinheckel,T.
    Human cathepsin L rescues the neurodegeneration and lethality in cathepsin B/L double-deficient mice
    Biol Chem387, 885-891. PubMed  Europe PubMed DOI  K
2005
25. Koike,M., Shibata,M., Waguri,S., Yoshimura,K., Tanida,I., Kominami,E., Gotow,T., Peters,C., von Figura,K., Mizushima,N., Saftig,P. and Uchiyama,Y.
    Participation of autophagy in storage of lysosomes in neurons from mouse models of neuronal ceroid-lipofuscinoses (Batten disease)
    Am J Pathol167, 1713-1728. PubMed  Europe PubMed DOI  K
2003
26. Levicar,N., Dewey,R.A., Daley,E., Bates,T.E., Davies,D., Kos,J., Pilkington,G.J. and Lah,T.T.
    Selective suppression of cathepsin L by antisense cDNA impairs human brain tumor cell invasion in vitro and promotes apoptosis
    Cancer Gene Ther10, 141-151. PubMed  Europe PubMed DOI  K
2002
27. Benavides,F., Starost,M.F., Flores,M., Gimenez-Conti,I.B., Guenet,J.L. and Conti,C.J.
    Impaired hair follicle morphogenesis and cycling with abnormal epidermal differentiation in nackt mice, a cathepsin L-deficient mutation
    Am J Pathol161, 693-703. PubMed  Europe PubMed DOI  K  M
28. [YEAR:11-6-2002]Felbor,U., Kessler,B., Mothes,W., Goebel,H.H., Ploegh,H.L., Bronson,R.T. and Olsen,B.R.
    Neuronal loss and brain atrophy in mice lacking cathepsins B and L
    Proc Natl Acad Sci U S A99, 7883-7888. PubMed  Europe PubMed DOI  K
29. [YEAR:30-4-2002]Stypmann,J., Glaser,K., Roth,W., Tobin,D.J., Petermann,I., Matthias,R., Monnig,G., Haverkamp,W., Breithardt,G., Schmahl,W., Peters,C. and Reinheckel,T.
    Dilated cardiomyopathy in mice deficient for the lysosomal cysteine peptidase cathepsin L
    Proc Natl Acad Sci U S A99, 6234-6239. PubMed  Europe PubMed DOI  K
2001
30. [YEAR:22-6-2001]Honey,K., Duff,M., Beers,C., Brissette,W.H., Elliott,E.A., Peters,C., Maric,M., Cresswell,P. and Rudensky,A.
    Cathepsin S regulates the expression of cathepsin L and the turnover of gamma-interferon-inducible lysosomal thiol reductase in B lymphocytes
    J Biol Chem276, 22573-22578. PubMed  Europe PubMed DOI  K
31. Reinheckel,T., Deussing,J., Roth,W. and Peters,C.
    Towards specific functions of lysosomal cysteine peptidases: phenotypes of mice deficient for cathepsin B or cathepsin L
    Biol Chem382, 735-741. PubMed  Europe PubMed DOI  K
2000
32. Roth,W., Deussing,J., Botchkarev,V.A., Pauly-Evers,M., Saftig,P., Hafner,A., Schmidt,P., Schmahl,W., Scherer,J., Anton-Lamprecht,I., von Figura,K., Paus,R. and Peters,C.
    Cathepsin L deficiency as molecular defect of furless: hyperproliferation of keratinocytes and pertubation of hair follicle cycling
    FASEB J14, 2075-2086. PubMed  Europe PubMed DOI  K  M