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Literature for peptidase S08.090: tripeptidyl-peptidase II

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

(References are filtered for relevance to Inhibitor. To remove the filter click here. See explanation.)

    2019
  1. Bialy,L.P., Kuckelkorn,U., Henklein,P., Fayet,J., Wilczynski,G.M., Kaminski,A. and Mlynarczuk-Bialy,I.
    Changes in spatio-temporal localization of tripeptidyl peptidase II (TPPII) in murine colon adenocarcinoma cells during aggresome formation: a microscopy study based on a novel fluorescent proteasome inhibitor
    Histol Histopathol34, 359-372. PubMed  Europe PubMed DOI  I
    2. 2018
  2. Bialy,L.P., Fayet,J., Wilczynski,G.M. and Mlynarczuk-Bialy,I.
    Semispecific TPPII inhibitor Ala-Ala-Phe-chloromethylketone (AAF-cmk) displays cytotoxic activity by induction of apoptosis, autophagy and protein aggregation in U937 cells
    Folia Histochem Cytobiol56, 185-194. PubMed  Europe PubMed DOI  I
  3. Vigneron,N., Ferrari,V., Van den Eynde,B.J., Cresswell,P. and Leonhardt,R.M.
    Cytosolic processing governs TAP-independent presentation of a critical melanoma antigen
    J Immunol201, 1875-1888. PubMed  Europe PubMed DOI  I
    4. 2015
  4. Wiemhoefer,A., Stargardt,A., van der Linden,W.A., Renner,M.C., van Kesteren,R.E., Stap,J., Raspe,M.A., Tomkinson,B., Kessels,H.W., Ovaa,H., Overkleeft,H.S., Florea,B. and Reits,E.A.
    Tripeptidyl peptidase II mediates levels of nuclear phosphorylated ERK1 and ERK2
    Mol Cell Proteomics14, 2177-2193. PubMed  Europe PubMed DOI  I
    5. 2010
  5. Villasevil,E.M., Guil,S., Lopez-Ferreras,L., Sanchez,C., Del Val,M. and Anton,L.C.
    Accumulation of polyubiquitylated proteins in response to Ala-Ala-Phe-chloromethylketone is independent of the inhibition of tripeptidyl peptidase II
    Biochim Biophys Acta1803, 1094-1105. PubMed  Europe PubMed DOI  I
    6. 2008
  6. Marcilla,M., Villasevil,E.M. and de Castro,J.A.
    Tripeptidyl peptidase II is dispensable for the generation of both proteasome-dependent and proteasome-independent ligands of HLA-B27 and other class I molecules
    Eur J Immunol38, 631-639. PubMed  Europe PubMed DOI  I
    7. 2005
  7. [YEAR:20-5-2005]Book,A.J., Yang,P., Scalf,M., Smith,L.M. and Vierstra,R.D.
    Tripeptidyl peptidase II. An oligomeric protease complex from Arabidopsis
    Plant Physiol138, 1046-1057. PubMed  Europe PubMed DOI  I
  8. [YEAR:17-11-2005]Ganellin,C.R., Bishop,P.B., Bambal,R.B., Chan,S.M., Leblond,B., Moore,A.N., Zhao,L., Bourgeat,P., Rose,C., Vargas,F. and Schwartz,J.C.
    Inhibitors of tripeptidyl peptidase II. 3. Derivation of butabindide by successive structure optimizations leading to a potential general approach to designing exopeptidase inhibitors
    J Med Chem48, 7333-7342. PubMed  Europe PubMed DOI  I
    9. 2003
  9. [YEAR:15-12-2003]Breslin,H.J., Miskowski,T.A., Kukla,M.J., De Winter,H.L., Somers,M.V., Roevens,P.W. and Kavash,R.W.
    Tripeptidyl-peptidase II (TPP II) inhibitory activity of (S)-2,3-dihydro-2-(1H-imidazol-2-yl)-1H-indoles, a systematic SAR evaluation. Part 2
    Bioorg Med Chem Lett13, 4467-4471. PubMed  Europe PubMed DOI  I
    10. 2002
  10. [YEAR:21-11-2002]Breslin,H.J., Miskowski,T.A., Kukla,M.J., Leister,W.H., De Winter,H.L., Gauthier,D.A., Somers,M.V., Peeters,D.C. and Roevens,P.W.
    Design, synthesis, and tripeptidyl peptidase II inhibitory activity of a novel series of (S)-2,3-dihydro-2-(4-alkyl-1H-imidazol-2-yl)-1H-indoles
    J Med Chem45, 5303-5310. PubMed  Europe PubMed DOI  I
    11. 2001
  11. Bury,M., Mlynarczuk,I., Pleban,E., Hoser,G., Kawiak,J. and Wojcik,C.
    Effects of an inhibitor of tripeptidyl peptidase II (Ala-Ala-Phe-chloromethylketone) and its combination with an inhibitor of the chymotrypsin-like activity of the proteasome (PSI) on apoptosis, cell cycle and proteasome activity in U937 cells
    Folia Histochem Cytobiol39, 131-132. PubMed  Europe PubMed  I
    12. 2000
  12. [YEAR:24-2-2000]Ganellin,C.R., Bishop,P.B., Bambal,R.B., Chan,S.M., Law,J.K., Marabout,B., Luthra,P.M., Moore,A.N., Peschard,O., Bourgeat,P., Rose,C., Vargas,F. and Schwartz,J.C.
    Inhibitors of tripeptidyl peptidase II. 2. Generation of the first novel lead inhibitor of cholecystokinin-8-inactivating peptidase: a strategy for the design of peptidase inhibitors
    J Med Chem43, 664-674. PubMed  Europe PubMed DOI  I
  13. Hilbi,H., Puro,R.J. and Zychlinsky,A.
    Tripeptidyl peptidase II promotes maturation of caspase-1 in Shigella flexneri-induced macrophage apoptosis
    Infect Immun68, 5502-5508. PubMed  Europe PubMed DOI  I
    14. 1996
  14. Rose,C., Vargas,F., Facchinetti,P., Bourgeat,P., Bambal,R.B., Bishop,P.B., Chan,S.M., Moore,A.N., Ganellin,C.R. and Schwartz,J.C.
    Characterization and inhibition of a cholecystokinin-inactivating serine peptidase
    Nature380, 403-409. PubMed  Europe PubMed DOI  I
    15. 1994
  15. [YEAR:1-11-1994]Tomkinson,B., Grehn,L., Fransson,B. and Zetterqvist,O.
    Use of a dehydroalanine-containing peptide as an efficient inhibitor of tripeptidyl peptidase II
    Arch Biochem Biophys314, 276-279. PubMed  Europe PubMed DOI  I

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