Literature for peptidase M04.005: pseudolysin

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

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    2024
  1. Metelkina,O., Konstantinovic,J., Klein,A., Shafiei,R., Fares,M., Alhayek,A., Yahiaoui,S., Elgaher,W.A.M., Haupenthal,J., Titz,A. and Hirsch,A.K.H.
    Dual inhibitors of Pseudomonas aeruginosa virulence factors M04.005 and LasB
    Chem Sci15, 13333-13342. PubMed  Europe PubMed DOI  I
  2. 2021
  3. Leiris,S., Davies,D.T., Sprynski,N., Castandet,J., Beyria,L., Bodnarchuk,M.S., Sutton,J.M., Mullins,T.M.G., Jones,M.W., Forrest,A.K., Pallin,T.D., Karunakar,P., Martha,S.K., Parusharamulu,B., Ramula,R., Kotha,V., Pottabathini,N., Pothukanuri,S., Lemonnier,M. and Everett,M.
    Virtual Screening Approach to Identifying a Novel and Tractable Series of Pseudomonas aeruginosa Elastase Inhibitors
    ACS Med Chem Lett12, 217-227. PubMed  Europe PubMed DOI  I
  4. 2020
  5. Ezawa,T., Saito,R., Suzuki,S., Sugiyama,S., Sylte,I. and Kurita,N.
    Protonation states of central amino acids in a zinc metalloprotease complexed with inhibitor: molecular mechanics optimizations and ab initio molecular orbital calculations
    Biophys Chem261, 106368-106368. PubMed  Europe PubMed DOI  S  I
  6. 2018
  7. Kany,A.M., Sikandar,A., Yahiaoui,S., Haupenthal,J., Walter,I., Empting,M., Kohnke,J. and Hartmann,R.W.
    Tackling Pseudomonas aeruginosa virulence by a hydroxamic acid-based LasB inhibitor
    ACS Chem Biol13, 2449-2455. PubMed  Europe PubMed DOI  I
  8. Kany,A.M., Sikandar,A., Haupenthal,J., Yahiaoui,S., Maurer,C.K., Proschak,E., Kohnke,J. and Hartmann,R.W.
    Binding mode characterization and early in vivo evaluation of fragment-like thiols as inhibitors of the virulence factor LasB from Pseudomonas aeruginosa
    ACS Infect Dis4, 988-997. PubMed  Europe PubMed DOI  I
  9. 2017
  10. Ara,A., Kadoya,R., Ishimura,H., Shimamura,K., Sylte,I. and Kurita,N.
    Specific interactions between zinc metalloproteinase and its inhibitors: Ab initio fragment molecular orbital calculations
    J Mol Graph Model75, 277-286. PubMed  Europe PubMed DOI  I
  11. 2016
  12. Sjoli,S., Nuti,E., Camodeca,C., Bilto,I., Rossello,A., Winberg,J.O., Sylte,I. and Adekoya,O.A.
    Synthesis, experimental evaluation and molecular modelling of hydroxamate derivatives as zinc metalloproteinase inhibitors
    Eur J Med Chem108, 141-153. PubMed  Europe PubMed DOI  I
  13. Szamosvari,D., Reichle,V.F., Jureschi,M. and Bottcher,T.
    Synthetic quinolone signal analogues inhibiting the virulence factor elastase of Pseudomonas aeruginosa
    Chem Commun (Camb)52, 13440-13443. PubMed  Europe PubMed DOI  I
  14. 2015
  15. Adekoya,O.A., Sjoli,S., Wuxiuer,Y., Bilto,I., Marques,S.M., Santos,M.A., Nuti,E., Cercignani,G., Rossello,A., Winberg,J.-O. and Sylte,I.
    Inhibition of pseudolysin and thermolysin by hydroxamate-based MMP inhibitors
    Eur J Med Chem89, 340-348. PubMed  Europe PubMed DOI  I
  16. 2013
  17. Fullagar,J.L., Garner,A.L., Struss,A.K., Day,J.A., Martin,D.P., Yu,J., Cai,X., Janda,K.D. and Cohen,S.M.
    Antagonism of a zinc metalloprotease using a unique metal-chelating scaffold: tropolones as inhibitors of P. aeruginosa elastase
    Chem Commun (Camb)49, 3197-3199. PubMed  Europe PubMed DOI  I
  18. 2012
  19. Carson,L., Cathcart,G.R., Ceri,H., Walker,B. and Gilmore,B.F.
    Comparison of the binding specificity of two bacterial metalloproteases, LasB of Pseudomonas aeruginosa and ZapA of Proteus mirabilis, using N-alpha mercaptoamide template-based inhibitor analogues
    Biochem Biophys Res Commun422, 316-320. PubMed  Europe PubMed DOI  I
  20. 2011
  21. Cathcart,G.R., Quinn,D., Greer,B., Harriott,P., Lynas,J.F., Gilmore,B.F. and Walker,B.
    Novel inhibitors of the Pseudomonas aeruginosa virulence factor LasB: a potential therapeutic approach for the attenuation of virulence mechanisms in pseudomonal infection
    Antimicrob Agents Chemother55, 2670-2678. PubMed  Europe PubMed DOI  I
  22. 2009
  23. Cathcart,G.R., Gilmore,B.F., Greer,B., Harriott,P. and Walker,B.
    Inhibitor profiling of the Pseudomonas aeruginosa virulence factor LasB using N-alpha mercaptoamide template-based inhibitors
    Bioorg Med Chem Lett19, 6230-6232. PubMed  Europe PubMed DOI  I
  24. 1997
  25. Louis,D., Kohlmann,M. and Wallach,J.
    Spectrophotometric assay for amidolytic activity of alkaline protease from Pseudomonas aeruginosa
    Anal Chim Acta345, 219-225.  A  I
  26. 1996
  27. Barletta,J.P., Angella,G., Balch,K.C., Dimova,H.G., Stern,G.A., Moser,M.T., van Setten,G.B. and Schultz,G.S.
    Inhibition of pseudomonal ulceration in rabbit corneas by a synthetic matrix metalloproteinase inhibitor
    Invest Ophthalmol Vis Sci37, 20-28. PubMed  Europe PubMed  I
  28. 1992
  29. [YEAR:1-6-1992]Yokota,S., Ohtsuka,H. and Noguchi,H.
    Monoclonal antibodies against Pseudomonas aeruginosa elastase: a neutralizing antibody which recognizes a conformational epitope related to an active site of elastase
    Eur J Biochem206, 587-593. PubMed  Europe PubMed DOI  I
  30. 1984
  31. [YEAR:5-6-1984]Poncz,L., Gerken,T.A., Dearborn,D.G., Grobelny,D. and Galardy,R.E.
    Inhibition of the elastase of Pseudomonas aeruginosa by N alpha-phosphoryl dipeptides and kinetics of spontaneous hydrolysis of the inhibitors
    Biochemistry23, 2766-2772. PubMed  Europe PubMed  I
  32. 1982
  33. Kessler,E., Israel,M., Landshman,N., Chechick,A. and Blumberg,S.
    In vitro inhibition of Pseudomonas aeruginosa elastase by metal-chelating peptide derivatives
    Infect Immun38, 716-723. PubMed  Europe PubMed  I
  34. 1980
  35. Nishino,N. and Powers,J.C.
    Pseudomonas aeruginosa elastase. Development of a new substrate, inhibitors, and an affinity ligand
    J Biol Chem255, 3482-3486. PubMed  Europe PubMed  I
  36. 1978
  37. Morihara,K. and Tsuzuki,H.
    Phosphoramidon as an inhibitor of elastase from Pseudomonas aeruginosa
    Jpn J Exp Med48, 81-84. PubMed  Europe PubMed  I