Literature for peptidase C25.002: gingipain K

Summary Alignment Sequences Sequence features Distribution Structure Literature Substrates

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    2020
  1. Arastu-Kapur,S., Nguyen,M., Raha,D., Ermini,F., Haditsch,U., Araujo,J., De Lannoy,I.A.M., Ryder,M.I., Dominy,S.S., Lynch,C. and Holsinger,L.J.
    Treatment of Porphyromonas gulae infection and downstream pathology in the aged dog by lysine-gingipain inhibitor COR388
    Pharmacol Res Perspect8, e00562-e00562. PubMed  Europe PubMed DOI  I
  2. 2019
  3. Guevara,T., Rodriguez-Banqueri,A., Lasica,A.M., Ksiazek,M., Potempa,B.A., Potempa,J. and Gomis-Ruth,F.X.
    Structural determinants of inhibition of Porphyromonas gingivalis gingipain K by KYT-36, a potent, selective, and bioavailable peptidase inhibitor
    Sci Rep9, 4935-4935. PubMed  Europe PubMed DOI  S  I
  4. 2017
  5. Kariu,T., Nakao,R., Ikeda,T., Nakashima,K., Potempa,J. and Imamura,T.
    Inhibition of gingipains and Porphyromonas gingivalis growth and biofilm formation by prenyl flavonoids
    J Periodontal Res52, 89-96. PubMed  Europe PubMed DOI  I
  6. 2014
  7. Haraguchi,A., Miura,M., Fujise,O., Hamachi,T. and Nishimura,F.
    Porphyromonas gingivalis gingipain is involved in the detachment and aggregation of Aggregatibacter actinomycetemcomitans biofilm
    Mol Oral Microbiol29, 131-143. PubMed  Europe PubMed DOI  I
  8. Kataoka,S., Baba,A., Suda,Y., Takii,R., Hashimoto,M., Kawakubo,T., Asao,T., Kadowaki,T. and Yamamoto,K.
    A novel, potent dual inhibitor of Arg-gingipains and Lys-gingipain as a promising agent for periodontal disease therapy
    FASEB J28, 3564-3578. PubMed  Europe PubMed DOI  I
  9. 2011
  10. Yongqing,T., Potempa,J., Pike,R.N. and Wijeyewickrema,L.C.
    The lysine-specific gingipain of Porphyromonas gingivalis: importance to pathogenicity and potential strategies for inhibition
    Adv Exp Med Biol712, 15-29. PubMed  Europe PubMed DOI  I
  11. 2007
  12. Smalley,J.W., Birss,A.J., Szmigielski,B. and Potempa,J.
    Sequential action of R- and K-specific gingipains of Porphyromonas gingivalis in the generation of the haem-containing pigment from oxyhaemoglobin
    Arch Biochem Biophys465, 44-49. PubMed  Europe PubMed DOI  I
  13. 2006
  14. [YEAR:9-3-2006]Bialas,A., Grembecka,J., Krowarsch,D., Otlewski,J., Potempa,J. and Mucha,A.
    Exploring the Sn binding pockets in gingipains by newly developed inhibitors: structure-based design, chemistry, and activity
    J Med Chem49, 1744-1753. PubMed  Europe PubMed DOI  I
  15. Cronan,C.A., Potempa,J., Travis,J. and Mayo,J.A.
    Inhibition of Porphyromonas gingivalis proteinases (gingipains) by chlorhexidine: synergistic effect of Zn(II)
    Oral Microbiol Immunol21, 212-217. PubMed  Europe PubMed DOI  I
  16. Matsushita,K., Imamura,T., Tancharoen,S., Tatsuyama,S., Tomikawa,M., Travis,J., Potempa,J., Torii,M. and Maruyama,I.
    Selective inhibition of Porphyromonas gingivalis growth by a factor Xa inhibitor, DX-9065a
    J Periodontal Res41, 171-176. PubMed  Europe PubMed DOI  I
  17. 2004
  18. [YEAR:10-9-2004]Kadowaki,T., Baba,A., Abe,N., Takii,R., Hashimoto,M., Tsukuba,T., Okazaki,S., Suda,Y., Asao,T. and Yamamoto,K.
    Suppression of pathogenicity of Porphyromonas gingivalis by newly developed gingipain inhibitors
    Mol Pharmacol66, 1599-1606. PubMed  Europe PubMed DOI  I
  19. Okamoto,M., Sugimoto,A., Leung,K.P., Nakayama,K., Kamaguchi,A. and Maeda,N.
    Inhibitory effect of green tea catechins on cysteine proteinases in Porphyromonas gingivalis
    Oral Microbiol Immunol19, 118-120. PubMed  Europe PubMed DOI  I
  20. 2002
  21. Curtis,M.A., Aduse Opoku,J., Rangarajan,M., Gallagher,A., Sterne,J.A., Reid,C.R., Evans,H.E. and Samuelsson,B.
    Attenuation of the virulence of Porphyromonas gingivalis by using a specific synthetic Kgp protease inhibitor
    Infect Immun70, 6968-6975. PubMed  Europe PubMed DOI  I
  22. Nassar,H., Chou,H.H., Khlgatian,M., Gibson,F.C., III, Van Dyke,T.E. and Genco,C.A.
    Role for fimbriae and lysine-specific cysteine proteinase gingipain K in expression of interleukin-8 and monocyte chemoattractant protein in Porphyromonas gingivalis-infected endothelial cells
    Infect Immun70, 268-276. PubMed  Europe PubMed DOI  I
  23. 2001
  24. Imamura,T., Matsushita,K., Travis,J. and Potempa,J.
    Inhibition of trypsin-like cysteine proteinases (gingipains) from Porphyromonas gingivalis by tetracycline and its analogues
    Antimicrobial Agents Chemother45, 2871-2876. PubMed  Europe PubMed DOI  I
  25. 1997
  26. Potempa,J., Pike,R. and Travis,J.
    Titration and mapping of the active site of cysteine proteinases from Porphyromonas gingivalis (Gingipains) using peptidyl chloromethanes
    Biol Chem378, 223-230. PubMed  Europe PubMed  I