Literature for peptidase C19.017: ubiquitin-specific peptidase 9X

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2025
1. Oak,S., Karajgikar,O., Gadewal,N., Sulkshane,P., Verma,T., Gupta,S. and Teni,T.
   The deubiquitinase inhibitor WP1130 drives nuclear aggregation and reactivation of mutant p53 for selective cancer cell targeting
   FEBS J PubMed  Europe PubMed DOI  I
2023
2. Song,N., Deng,L., Zeng,L., He,L., Liu,C., Liu,L. and Fu,R.
   USP9X deubiquitinates and stabilizes CDC123 to promote breast carcinogenesis through regulating cell cycle
   Mol Carcinog62, 1487-1503. PubMed  Europe PubMed DOI  I
3. Wang,S., Huo,X., Yang,Y., Mo,Y., Kollipara,R.K. and Kittler,R.
   Ablation of EWS-FLI1 by USP9X inhibition suppresses cancer cell growth in Ewing sarcoma
   Cancer Lett552, 215984-215984. PubMed  Europe PubMed DOI  I
2022
4. Sheng,L., Chen,J., Tong,Y., Zhang,Y., Feng,Q. and Tang,Z.
   USP9x promotes CD8 (+) T-cell dysfunction in association with autophagy inhibition in septic liver injury
   Acta Biochim Biophys Sin (Shanghai)54, 1-10. PubMed  Europe PubMed DOI  I
2021
5. Barban do Patrocinio,A., Cabral,F.J., de Paiva,T.H., Magalhaes,L.G., Paula,L.A.L., Brigato,O.M., Guerra-Sa,R. and Rodrigues,V.
   Deubiquitinating enzymes as possible drug targets for schistosomiasis
   Acta Trop217, 105856-105856. PubMed  Europe PubMed DOI  I
2019
6. Akiyama,H., Umezawa,Y., Ishida,S., Okada,K., Nogami,A. and Miura,O.
   Inhibition of USP9X induces apoptosis in FLT3-ITD-positive AML cells cooperatively by inhibiting the mutant kinase through aggresomal translocation and inducing oxidative stress
   Cancer Lett453, 84-94. PubMed  Europe PubMed DOI  I
7. Lu,Q., Zhang,F.L., Lu,D.Y., Shao,Z.M. and Li,D.Q.
   USP9X stabilizes BRCA1 and confers resistance to DNA-damaging agents in human cancer cells
   Cancer Med8, 6730-6740. PubMed  Europe PubMed DOI  M  I
2018
8. Ma,T., Chen,W., Zhi,X., Liu,H., Zhou,Y., Chen,B.W., Hu,L., Shen,J., Zheng,X., Zhang,S., Zhang,B., Li,H. and Liang,T.
   USP9X inhibition improves gemcitabine sensitivity in pancreatic cancer by inhibiting autophagy
   Cancer Lett436, 129-138. PubMed  Europe PubMed DOI  I
2016
9. Karpel-Massler,G., Banu,M.A., Shu,C., Halatsch,M.E., Westhoff,M.A., Bruce,J.N., Canoll,P. and Siegelin,M.D.
   Inhibition of deubiquitinases primes glioblastoma cells to apoptosis in vitro and in vivo
   Oncotarget7, 12791-12805. PubMed  Europe PubMed DOI  I
2015
10. Kushwaha,D., O'Leary,C., Cron,K.R., Deraska,P., Zhu,K., D'Andrea,A.D. and Kozono,D.
    USP9X inhibition promotes radiation-induced apoptosis in non-small cell lung cancer cells expressing mid-to-high MCL1
    Cancer Biol Ther16, 392-401. PubMed  Europe PubMed DOI  I
11. Lawson,A.P., Long,M.J., Coffey,R.T., Qian,Y., Weerapana,E., El Oualid,F. and Hedstrom,L.
    Naturally occurring isothiocyanates exert anticancer effects by inhibiting deubiquitinating enzymes
    Cancer Res75, 5130-5142. PubMed  Europe PubMed DOI  I
12. Peterson,L.F., Sun,H., Liu,Y., Potu,H., Kandarpa,M., Ermann,M., Courtney,S.M., Young,M., Showalter,H.D., Sun,D., Jakubowiak,A., Malek,S.N., Talpaz,M. and Donato,N.J.
    Targeting deubiquitinase activity with a novel small-molecule inhibitor as therapy for B-cell malignancies
    Blood125, 3588-3597. PubMed  Europe PubMed DOI  I
2014
13. Peng,Z., Maxwell,D.S., Sun,D., Bhanu Prasad,B.A., Schuber,P.T., Jr., Pal,A., Ying,Y., Han,D., Gao,L., Wang,S., Levitzki,A., Kapuria,V., Talpaz,M., Young,M., Showalter,H.D., Donato,N.J. and Bornmann,W.G.
    Degrasyn-like symmetrical compounds: possible therapeutic agents for multiple myeloma (MM-I)
    Bioorg Med Chem22, 1450-1458. PubMed  Europe PubMed DOI  I
14. Wang,S., Kollipara,R.K., Srivastava,N., Li,R., Ravindranathan,P., Hernandez,E., Freeman,E., Humphries,C.G., Kapur,P., Lotan,Y., Fazli,L., Gleave,M.E., Plymate,S.R., Raj,G.V., Hsieh,J.T. and Kittler,R.
    Ablation of the oncogenic transcription factor ERG by deubiquitinase inhibition in prostate cancer
    Proc Natl Acad Sci U S A111, 4251-4256. PubMed  Europe PubMed DOI  I