Literature for peptidase C01.149: TgCPL peptidase (Toxoplasma-type)

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

(References are filtered for relevance to Inhibitor. To remove the filter click here. See explanation.)

    2020
  1. Zwicker,J.D., Smith,D., Guerra,A.J., Hitchens,J.R., Haug,N., Vander Roest,S., Lee,P., Wen,B., Sun,D., Wang,L., Keep,R., Xiang,J., Carruthers,V.B. and Larsen,S.D.
    Discovery and optimization of triazine nitrile inhibitors of Toxoplasma gondii cathepsin L for the potential treatment of chronic toxoplasmosis in the CNS
    ACS Chem Neurosci11, 2450-2463. PubMed  Europe PubMed DOI  I
  2. 2018
  3. Zwicker,J.D., Diaz,N.A., Guerra,A.J., Kirchhoff,P.D., Wen,B., Sun,D., Carruthers,V.B. and Larsen,S.D.
    Optimization of dipeptidic inhibitors of cathepsin L for improved Toxoplasma gondii selectivity and CNS permeability
    Bioorg Med Chem Lett28, 1972-1980. PubMed  Europe PubMed DOI  I
  4. 2011
  5. Dou,Z. and Carruthers,V.B.
    Cathepsin proteases in Toxoplasma gondii
    Adv Exp Med Biol712, 49-61. PubMed  Europe PubMed DOI  I
  6. 2009
  7. Larson,E.T., Parussini,F., Huynh,M.H., Giebel,J.D., Kelley,A.M., Zhang,L., Bogyo,M., Merritt,E.A. and Carruthers,V.B.
    Toxoplasma gondii cathepsin L is the primary target of the invasion-inhibitory compound morpholinurea-leucyl-homophenyl-vinyl sulfone phenyl
    J Biol Chem284, 26839-26850. PubMed  Europe PubMed DOI  I