Literature for peptidase A01.075: plasmepsin-5 (Plasmodium sp.)

(References are filtered for relevance to Inhibitor. To remove the filter click here. See explanation.)

2024
1. Das,A., Rajkhowa,S., Sinha,S. and Zaki,M.E.A.
   Unveiling potential repurposed drug candidates for Plasmodium falciparum through in silico evaluation: A synergy of structure-based approaches, structure prediction, and molecular dynamics simulations
   Comput Biol Chem110, 108048-108048. PubMed  Europe PubMed DOI  I
2023
2. Sulyman,A.O., Aje,O.O., Ajani,E.O., Abdulsalam,R.A., Balogun,F.O. and Sabiu,S.
   Bioprospection of Selected Plant Secondary Metabolites as Modulators of the Proteolytic Activity of Plasmodium falciparum Plasmepsin V
   Biomed Res Int2023, 6229503-6229503. PubMed  Europe PubMed DOI  I
2019
3. Meissner,K.A., Kronenberger,T., Maltarollo,V.G., Trossini,G.H.G. and Wrenger,C.
   Targeting the Plasmodium falciparum plasmepsin V by ligand-based virtual screening
   Chem Biol Drug Des93, 300-312. PubMed  Europe PubMed DOI  I
2018
4. Nguyen,W., Hodder,A.N., de Lezongard,R.B., Czabotar,P.E., Jarman,K.E., O'Neill,M.T., Thompson,J.K., Jousset Sabroux,H., Cowman,A.F., Boddey,J.A. and Sleebs,B.E.
   Enhanced antimalarial activity of plasmepsin V inhibitors by modification of the P2 position of PEXEL peptidomimetics
   Eur J Med Chem154, 182-198. PubMed  Europe PubMed DOI  I
5. Sittikul,P., Songtawee,N., Kongkathip,N. and Boonyalai,N.
   In vitro and in silico studies of naphthoquinones and peptidomimetics toward Plasmodium falciparum plasmepsin V
   Biochimie152, 159-173. PubMed  Europe PubMed DOI  I
2016
6. Bedi,R.K., Patel,C., Mishra,V., Xiao,H., Yada,R.Y. and Bhaumik,P.
   Understanding the structural basis of substrate recognition by Plasmodium falciparum plasmepsin V to aid in the design of potent inhibitors
   Sci Rep6, 31420-31420. PubMed  Europe PubMed DOI  I
7. Gazdik,M., Jarman,K.E., O'Neill,M.T., Hodder,A.N., Lowes,K.N., Jousset Sabroux,H., Cowman,A.F., Boddey,J.A. and Sleebs,B.E.
   Exploration of the P3 region of PEXEL peptidomimetics leads to a potent inhibitor of the Plasmodium protease, plasmepsin V
   Bioorg Med Chem24, 1993-2010. PubMed  Europe PubMed DOI  I
8. L,M. and Soliman,M.E.
   The binding landscape of plasmepsin V and the implications for flap dynamics
   Mol Biosyst12, 1457-1467. PubMed  Europe PubMed DOI  I
2015
9. Gambini,L., Rizzi,L., Pedretti,A., Taglialatela-Scafati,O., Carucci,M., Pancotti,A., Galli,C., Read,M., Giurisato,E., Romeo,S. and Russo,I.
   Picomolar inhibition of plasmepsin V, an essential malaria protease, achieved exploiting the prime region
   PLoS ONE10, e0142509-e0142509. PubMed  Europe PubMed DOI  I
10. Gazdik,M., O'Neill,M.T., Lopaticki,S., Lowes,K.N., Smith,B.J., Cowman,A.F., Boddey,J.A. and Sleebs,B.E.
    The effect of N-methylation on transition state mimetic inhibitors of the Plasmodium protease, plasmepsin V
    MedChemComm6, 437-443. DOI  I
11. Goldberg,D.E.
    Plasmepsin V shows its carnivorous side
    Nat Struct Mol Biol22, 647-648. PubMed  Europe PubMed DOI  P  I
12. Hodder,A.N., Sleebs,B.E., Czabotar,P.E., Gazdik,M., Xu,Y., O'Neill,M.T., Lopaticki,S., Nebl,T., Triglia,T., Smith,B.J., Lowes,K., Boddey,J.A. and Cowman,A.F.
    Structural basis for plasmepsin V inhibition that blocks export of malaria proteins to human erythrocytes
    Nat Struct Mol Biol22, 590-596. PubMed  Europe PubMed DOI  S  I
2014
13. Sedwick,C.
    Plasmepsin V, a secret weapon against malaria
    PLoS Biol12, e1001898-e1001898. PubMed  Europe PubMed DOI  I
14. Sleebs,B.E., Gazdik,M., O'Neill,M.T., Rajasekaran,P., Lopaticki,S., Lackovic,K., Lowes,K., Smith,B.J., Cowman,A.F. and Boddey,J.A.
    Transition state mimetics of the Plasmodium export element are potent inhibitors of plasmepsin V from P. falciparum and P. vivax
    J Med Chem57, 7644-7662. PubMed  Europe PubMed DOI  T  I
15. Sleebs,B.E., Lopaticki,S., Marapana,D.S., O'Neill,M.T., Rajasekaran,P., Gazdik,M., Gunther,S., Whitehead,L.W., Lowes,K.N., Barfod,L., Hviid,L., Shaw,P.J., Hodder,A.N., Smith,B.J., Cowman,A.F. and Boddey,J.A.
    Inhibition of Plasmepsin V Activity Demonstrates Its Essential Role in Protein Export, PfEMP1 Display, and Survival of Malaria Parasites
    PLoS Biol12, e1001897-e1001897. PubMed  Europe PubMed DOI  I
2012
16. Meyers,M.J. and Goldberg,D.E.
    Recent advances in plasmepsin medicinal chemistry and implications for future antimalarial drug discovery efforts
    Curr Top Med Chem12, 445-455. PubMed  Europe PubMed DOI  I
2002
17. Nezami,A. and Freire,E.
    The integration of genomic and structural information in the development of high affinity plasmepsin inhibitors
    Int J Parasitol32, 1669-1676. PubMed  Europe PubMed DOI  I