Summary for peptidase homologue T01.986: proteasome subunit beta 1

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Pharma

 

Names
MEROPS Nameproteasome subunit beta 1
Other namesproteasome subunit C5 (Homo sapiens), PRS3 g.p. (Saccharomyces cerevisiae), PSMB1 g.p. (Homo sapiens)
Domain architecture
MEROPS Classification
Classification Clan PB >> Subclan PB(T) >> Family T1 >> Subfamily A >> T01.986
Holotypeproteasome subunit beta 1 (Homo sapiens), Uniprot accession P20618 (peptidase unit: 39-230), MERNUM MER0000551
History Identifier created: MEROPS 3.02 (25 June 1998)
Activity
Catalytic typeNon-peptidase homologue
NC-IUBMBSubclass 3.4 (Peptidases) >> Sub-subclass 3.4.25 (Threonine-type endopeptidases) >> Peptidase 3.4.25.1
EnzymologyBRENDA database
Activity statushuman: inactive
mouse: inactive
PhysiologyOne of the non-peptidase subunits of the 20 S proteasome, but homolgous with the catalytically-active beta subunits.
Pathways KEGGProteasome
Other databases TREEFAMhttp://www.treefam.org/family/TF106218
PANTHERhttp://www.pantherdb.org/panther/familyList.do?searchType=basic&fieldName=all&listType=6&fieldValue=PTHR11599:SF59
Human genetics
Gene symbol Locus Megabases Ensembl Entrez gene Gene Cards OMIM
PSMB1 7p12-p13 ENSG00000008018 5689 PSMB1 602017