$VAR1 = undef;

Summary for peptidase S32.002: porcine reproductive and respiratory syndrome virus nsp4 peptidase

Names
MEROPS Name	porcine reproductive and respiratory syndrome virus nsp4 peptidase
Other names	PRRSV 3CL protease, PRRSV 3C-like peptidase, PRRSV nsp4 peptidase

Domain architecture

MEROPS Classification
Classification	Clan PA >> Subclan PA(S) >> Family S32 >> Subfamily (none) >> S32.002
Holotype	porcine reproductive and respiratory syndrome virus nsp4 peptidase, Uniprot accession Q04561 (peptidase unit: 1694-1896), MERNUM MER0001868
History	Identifier created: MEROPS 8.5 (24 August 2009)

Activity
Catalytic type	Serine
NC-IUBMB	Not yet included in IUBMB recommendations.
Cleavage site specificity	Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern	-/-/ln/EGsa/-/-/- (based on 10 cleavages)

Specificity matrix

Amino acid	P4	P3	P2	P1	P1'	P2'	P3'	P4'
Gly	0	1	0	1	7	1	0	0
Pro	1	0	0	0	0	0	0	0
Ala	1	0	1	0	1	3	0	1
Val	1	1	1	0	0	0	0	1
Leu	0	1	5	0	0	2	2	1
Ile	0	0	0	0	0	0	0	0
Met	1	0	0	0	0	0	0	1
Phe	1	1	0	0	0	0	1	1
Tyr	1	0	0	0	0	0	0	1
Trp	0	0	0	0	0	0	0	1
Ser	2	1	0	0	2	1	1	1
Thr	0	1	1	0	0	0	2	0
Cys	0	1	0	0	0	0	1	0
Asn	1	1	2	0	0	1	0	0
Gln	0	1	0	0	0	0	0	0
Asp	0	0	0	0	0	0	0	0
Glu	0	0	0	9	0	1	1	0
Lys	1	0	0	0	0	1	2	0
Arg	0	0	0	0	0	0	0	2
His	0	1	0	0	0	0	0	0