$VAR1 = undef;

Summary for peptidase S14.003: peptidase Clp (type 3)

Names
MEROPS Name	peptidase Clp (type 3)
Other names	CLPP g.p. (Homo sapiens), Clpp g.p. (Mus musculus)

Domain architecture

MEROPS Classification
Classification	Clan SK >> Subclan (none) >> Family S14 >> Subfamily (none) >> S14.003
Holotype	peptidase Clp (type 3) (Homo sapiens), Uniprot accession Q16740 (peptidase unit: 43-249), MERNUM MER0002211
History	Identifier created: MEROPS 3.02 (25 June 1998)

Activity
Catalytic type	Serine
NC-IUBMB	Not yet included in IUBMB recommendations.
Activity status	human: active (Adam et al., 2004) mouse: active (by similarity to human)
Other databases	TREEFAM	http://www.treefam.org/family/TF105002
Cleavage site specificity	Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern	A/pel/-/mgla/L/Vl/pv (based on 10 cleavages)

Specificity matrix

Amino acid	P4	P3	P2	P1	P1'	P2'	P3'	P4'
Gly	1	0	0	2	0	0	1	0
Pro	0	4	0	0	0	0	0	5
Ala	6	0	1	1	5	0	0	0
Val	1	1	0	0	1	0	6	2
Leu	1	2	0	2	1	6	2	0
Ile	0	1	1	0	0	0	0	0
Met	0	0	0	5	0	0	0	0
Phe	0	0	0	0	1	1	0	0
Tyr	0	0	1	0	1	1	1	0
Trp	0	0	0	0	0	0	0	0
Ser	0	0	1	0	1	0	0	0
Thr	0	0	0	0	0	0	0	1
Cys	0	0	0	0	0	0	0	0
Asn	0	0	0	0	0	0	0	0
Gln	0	0	0	0	0	0	0	0
Asp	0	0	0	0	0	0	0	0
Glu	0	2	2	0	0	0	0	1
Lys	0	0	0	0	0	0	0	0
Arg	0	0	1	0	0	0	0	0
His	1	0	2	0	0	1	0	0