$VAR1 = undef;

Summary for peptidase S08.007: thermitase

Names
MEROPS Name	thermitase
Other names	thermophilic Streptomyces serine proteinase

Domain architecture

MEROPS Classification
Classification	Clan SB >> Subclan (none) >> Family S8 >> Subfamily A >> S08.007
Holotype	thermitase (Thermoactinomyces vulgaris), Uniprot accession P04072 (peptidase unit: 8-278), MERNUM MER0000333
History	Identifier created: Handbook of Proteolytic Enzymes (1998) Academic Press, London.

Activity
Catalytic type	Serine
Peplist	Included in the Peplist with identifier PL00344
NC-IUBMB	Subclass 3.4 (Peptidases) >> Sub-subclass 3.4.21 (Serine endopeptidases) >> Peptidase 3.4.21.66
Enzymology	BRENDA database
Proteolytic events	CutDB database (8 cleavages)
Cleavage site specificity	Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern	-/-/a/--/-/-/- (based on 13 cleavages)

Specificity matrix

Amino acid	P4	P3	P2	P1	P1'	P2'	P3'	P4'
Gly	2	2	2	0	1	0	1	1
Pro	1	0	1	0	0	1	1	1
Ala	0	4	4	3	1	0	1	1
Val	2	1	0	0	1	0	2	0
Leu	1	0	0	2	1	3	0	1
Ile	0	0	0	0	0	0	0	0
Met	0	0	0	0	0	0	0	0
Phe	1	1	2	3	1	1	1	0
Tyr	0	0	0	1	2	1	0	1
Trp	0	0	0	0	0	0	0	0
Ser	0	1	0	1	0	0	0	1
Thr	0	0	0	0	1	1	1	0
Cys	0	0	0	0	0	0	0	0
Asn	0	1	1	0	0	0	0	0
Gln	0	0	1	1	0	0	0	0
Asp	0	0	0	0	0	0	0	0
Glu	1	1	1	0	0	1	0	1
Lys	0	0	0	0	0	0	1	1
Arg	1	1	0	1	0	0	0	0
His	0	0	1	1	2	0	0	0