$VAR1 = undef;

Summary for peptidase S01.020: kallikrein-related peptidase 12

Names
MEROPS Name	kallikrein-related peptidase 12
Other names	kallikrein 12, KLK-L5 [obs.] g.p. (Homo sapiens), kallikrein-like protein 5, KLK12 g.p. (Homo sapiens)

Domain architecture

MEROPS Classification
Classification	Clan PA >> Subclan PA(S) >> Family S1 >> Subfamily A >> S01.020
Holotype	kallikrein-related peptidase 12 (Homo sapiens), Uniprot accession Q9UKR0 (peptidase unit: 22-235), MERNUM MER0006038
History	Identifier created: MEROPS 4.0 (27 January 2000)

Activity
Catalytic type	Serine
NC-IUBMB	Not yet included in IUBMB recommendations.
Activity status	human: putative mouse: putative
Other databases	WIKIPEDIA	http://en.wikipedia.org/wiki/KLK12
Cleavage site specificity	Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern	-/-/std/KRilv/ilv/g/G (based on 20 cleavages)

Specificity matrix

Amino acid	P4	P3	P2	P1	P1'	P2'	P3'	P4'
Gly	0	2	0	0	1	0	6	11
Pro	0	0	2	0	0	0	3	0
Ala	2	2	0	0	1	0	0	1
Val	0	0	0	0	3	5	0	1
Leu	0	1	2	0	3	5	0	0
Ile	3	0	0	0	9	6	0	0
Met	2	0	0	0	0	0	1	1
Phe	0	1	0	0	0	1	0	0
Tyr	0	0	0	0	0	0	1	0
Trp	0	0	0	0	0	0	0	0
Ser	3	3	6	0	0	2	0	0
Thr	2	1	5	0	0	0	0	1
Cys	0	0	0	0	0	0	1	0
Asn	1	0	2	0	1	0	4	1
Gln	2	3	0	0	0	0	0	1
Asp	2	2	3	0	0	1	1	0
Glu	2	4	0	0	0	0	1	2
Lys	0	1	0	11	1	0	1	0
Arg	0	0	0	9	1	0	0	1
His	0	0	0	0	0	0	1	0