$VAR1 = undef;

Summary for peptidase M72.001: peptidyl-Asp metallopeptidase

Summary Alignment Sequences Sequence features Distribution Literature Substrates

 

Names
MEROPS Namepeptidyl-Asp metallopeptidase
Other namesAspN, endoproteinase Asp-N, Mep72 peptidase, PA2783 g.p. (Pseudomonas aeruginosa)
Domain architecture
MEROPS Classification
Classification Clan MA >> Subclan MA(M) >> Family M72 >> Subfamily (none) >> M72.001
Holotypepeptidyl-Asp metallopeptidase (Pseudomonas aeruginosa) (peptidase unit: 27-267), MERNUM MER0022935
History Identifier created: MEROPS 6.3 (23 June 2003)
Activity
Catalytic typeMetallo
NC-IUBMBSubclass 3.4 (Peptidases) >> Sub-subclass 3.4.24 (Metalloendopeptidases) >> Peptidase 3.4.24.33
EnzymologyBRENDA database
Proteolytic eventsCutDB database (3 cleavages)
BiotechnologyReagent in protein sequencing.
Other databases PANTHERhttp://www.pantherdb.org/panther/familyList.do?searchType=basic&fieldName=all&listType=6&fieldValue=PTHR31490:SF1
Cleavage site specificity Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern-/-/-/-Scissile bondD/-/-/- (based on 21 cleavages)
weblogo
Specificity matrix
 
Amino acid P4 P3 P2 P1 P1' P2' P3' P4'
Gly 0 1 3 0 0 3 1 2
Pro 0 1 0 1 0 1 0 0
Ala 2 0 1 2 0 0 2 2
Val 0 1 1 0 0 2 1 0
Leu 2 1 0 3 0 0 0 0
Ile 0 3 0 0 0 1 0 1
Met 1 0 0 0 0 1 0 0
Phe 0 2 1 0 0 1 0 0
Tyr 0 0 1 0 0 2 3 0
Trp 1 1 0 0 0 0 0 0
Ser 3 1 2 3 0 2 2 0
Thr 1 0 1 3 0 1 1 2
Cys 1 1 2 1 0 0 0 1
Asn 1 0 2 1 0 3 1 0
Gln 1 0 0 1 0 0 2 1
Asp 1 1 0 0 20 0 0 0
Glu 1 0 2 1 0 1 1 4
Lys 2 2 2 2 0 0 0 3
Arg 2 2 0 1 0 1 4 2
His 0 2 1 0 0 0 1 1