$VAR1 = undef;

Summary for peptidase M24.028: mitochondrial methionyl aminopeptidase

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Literature Substrates

 

Names
MEROPS Namemitochondrial methionyl aminopeptidase
Other nameshomologue M24Mm1 (Mus musculus), Mername-AA160 peptidase, Mername-AA021 peptidase
Domain architecture
MEROPS Classification
Classification Clan MG >> Subclan (none) >> Family M24 >> Subfamily A >> M24.028
Holotypemitochondrial methionyl aminopeptidase (Mus musculus), Uniprot accession Q9CPW9 (peptidase unit: 84-335), MERNUM MER0013929
History Identifier created: MEROPS 5.4 (23 March 2001)
Activity
Catalytic typeMetallo
NC-IUBMBNot yet included in IUBMB recommendations.
Activity statushuman: putative
mouse: putative
Other databases TREEFAMhttp://www.treefam.org/family/TF325318
Cleavage site specificity Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern-/-/-/MScissile bondGastv/d/v/ea (based on 131 cleavages)
weblogo
Specificity matrix
 
Amino acid P4 P3 P2 P1 P1' P2' P3' P4'
Gly 0 0 0 0 52 12 6 1
Pro 0 0 0 0 10 9 18 10
Ala 0 0 0 0 25 10 13 26
Val 0 0 0 0 11 11 34 15
Leu 0 0 0 0 0 3 5 4
Ile 0 0 0 0 0 3 9 4
Met 0 0 0 131 1 0 0 0
Phe 0 0 0 0 0 6 4 2
Tyr 0 0 0 0 0 3 4 1
Trp 0 0 0 0 0 0 1 2
Ser 0 0 0 0 19 5 3 3
Thr 0 0 0 0 13 2 7 6
Cys 0 0 0 0 0 0 0 2
Asn 0 0 0 0 0 3 1 3
Gln 0 0 0 0 0 1 10 2
Asp 0 0 0 0 0 44 1 3
Glu 0 0 0 0 0 9 3 39
Lys 0 0 0 0 0 1 8 4
Arg 0 0 0 0 0 4 3 3
His 0 0 0 0 0 5 1 1
Human genetics
Gene symbol Locus Megabases Ensembl Entrez gene Gene Cards OMIM
2q31.1 ENSG00000172878 254042
Mouse genetics
Gene symbol Position Megabases Ensembl Entrez gene MGI
Metapl1 2:C3 ENSMUSG00000041921 66559 MGI:1913809