$VAR1 = undef;
Summary for peptidase M14.010: carboxypeptidase A3
| Names | |
|---|---|
| MEROPS Name | carboxypeptidase A3 |
| Other names | mast cell carboxypeptidase A, tissue carboxypeptidase A |
| Domain architecture |
|---|
| MEROPS Classification | |
|---|---|
| Classification | Clan MC >> Subclan (none) >> Family M14 >> Subfamily A >> M14.010 |
| Holotype | carboxypeptidase A3 (Rattus norvegicus), Uniprot accession P21961 (peptidase unit: 108-417), MERNUM MER0001189 |
| History | Identifier created: Handbook of Proteolytic Enzymes (1998) Academic Press, London. |
| Activity | |||
|---|---|---|---|
| Catalytic type | Metallo | ||
| Peplist | Included in the Peplist with identifier PL00214 | ||
| NC-IUBMB | Not yet included in IUBMB recommendations. | ||
| Proteolytic events | CutDB database (1 cleavage) | ||
| Activity status | human: active (Springman, 2004) mouse: active (Reynolds et al., 1989) | ||
| Pathways | KEGG | Pancreatic secretion | |
| KEGG | Protein digestion and absorption | ||
| KEGG | Renin-angiotensin system | ||
| Other databases | TREEFAM | http://www.treefam.org/family/TF317197 | |
| Human genetics | ||||||
|---|---|---|---|---|---|---|
| Gene symbol | Locus | Megabases | Ensembl | Entrez gene | Gene Cards | OMIM |
| CPA3 | 3q21-q25 | ENSG00000163751 | 1359 | CPA3 | 114851 | |
| Mouse genetics | ||||||
| Gene symbol | Position | Megabases | Ensembl | Entrez gene | MGI | |
| Cpa3 | 3:A2 | ENSMUSG00000001865 | 12873 | MGI:88479 | ||
