$VAR1 = undef;

Summary for peptidase M13.014: neprilysin-4 (Drosophila melanogaster)

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Literature Substrates

 

Names
MEROPS Nameneprilysin-4 (Drosophila melanogaster)
Other namesCG4058 g.p. (Drosophila melanogaster), Nep4
Domain architecture
MEROPS Classification
Classification Clan MA >> Subclan MA(E) >> Family M13 >> Subfamily (none) >> M13.014
Holotypeneprilysin-4 (Drosophila melanogaster) (peptidase unit: 390-1040), MERNUM MER0019831
History Identifier created: MEROPS 9.1 (28 January 2010)
Activity
Catalytic typeMetallo
NC-IUBMBNot yet included in IUBMB recommendations.
Other databases PANTHERhttp://www.pantherdb.org/panther/familyList.do?searchType=basic&fieldName=all&listType=6&fieldValue=PTHR11733:SF184
Cleavage site specificity Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern-/-/-/gScissile bondfl/-/-/- (based on 32 cleavages)
weblogo
Specificity matrix
 
Amino acid P4 P3 P2 P1 P1' P2' P3' P4'
Gly 3 0 0 11 3 3 5 2
Pro 2 4 0 3 0 0 1 1
Ala 3 2 3 1 0 2 1 1
Val 1 0 2 0 1 1 0 1
Leu 2 2 3 2 7 4 2 1
Ile 0 0 1 0 0 1 0 0
Met 0 0 3 0 2 1 1 2
Phe 1 5 7 4 12 2 3 0
Tyr 3 2 0 0 2 0 1 1
Trp 0 0 0 0 2 1 0 1
Ser 3 2 1 2 1 3 2 1
Thr 0 1 0 2 1 1 0 1
Cys 0 0 0 0 0 0 0 0
Asn 0 2 2 1 0 1 1 0
Gln 4 2 4 1 0 1 0 0
Asp 0 1 1 0 0 1 1 1
Glu 0 0 0 0 0 0 0 0
Lys 1 1 0 0 0 0 0 0
Arg 3 3 4 4 1 3 0 1
His 1 2 1 1 0 1 0 0