$VAR1 = undef;
Summary for peptidase M12.142: atrolysin A
| Names | |
|---|---|
| MEROPS Name | atrolysin A |
| Other names | Crotalus atrox venom metalloendopeptidase a |
| Domain architecture |
|---|
| MEROPS Classification | |
|---|---|
| Classification | Clan MA >> Subclan MA(M) >> Family M12 >> Subfamily B >> M12.142 |
| Holotype | atrolysin A (Crotalus atrox), Uniprot accession Q92043 (peptidase unit: 1-202), MERNUM MER0002419 |
| History | Identifier created: Handbook of Proteolytic Enzymes (1998) Academic Press, London. |
| Activity | |||
|---|---|---|---|
| Catalytic type | Metallo | ||
| Peplist | Included in the Peplist with identifier PL00183 | ||
| NC-IUBMB | Subclass 3.4 (Peptidases) >> Sub-subclass 3.4.24 (Metalloendopeptidases) >> Peptidase 3.4.24.1 | ||
| Enzymology | BRENDA database | ||
| Proteolytic events | CutDB database (2 cleavages) | ||
| Physiology | Likely role in snake venom toxicity. Potent hemorrhagic toxin, degrading vascular basement membrane. | ||
