$VAR1 = undef;

Summary for peptidase M12.032: LAST peptidase (Limulus-type)

Summary Alignment Tree Sequences Sequence features Distribution Literature Substrates

 

Names
MEROPS NameLAST peptidase (Limulus-type)
Other namesLimulus astacin
Domain architecture
MEROPS Classification
Classification Clan MA >> Subclan MA(M) >> Family M12 >> Subfamily A >> M12.032
HolotypeLAST peptidase (Limulus-type) (Limulus polyphemus) (peptidase unit: 53-237), MERNUM MER0140388
History Identifier created: MEROPS 8.3 (22 December 2008)
Activity
Catalytic typeMetallo
NC-IUBMBNot yet included in IUBMB recommendations.
Cleavage site specificity Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern-/-/a/-Scissile bondag/p/-/- (based on 78 cleavages)
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Specificity matrix
 
Amino acid P4 P3 P2 P1 P1' P2' P3' P4'
Gly 8 5 5 5 15 1 7 14
Pro 8 8 6 1 3 35 18 4
Ala 6 13 23 20 32 9 10 15
Val 7 10 2 0 2 4 9 4
Leu 3 5 7 1 3 2 3 4
Ile 3 6 6 0 2 1 2 2
Met 3 2 2 2 0 0 2 0
Phe 5 1 0 6 0 2 2 5
Tyr 0 1 1 3 2 1 1 1
Trp 0 1 1 0 0 1 0 2
Ser 6 4 3 7 1 2 2 3
Thr 2 4 4 1 4 2 6 2
Cys 1 0 4 1 0 1 0 0
Asn 2 1 1 3 2 0 2 4
Gln 3 5 3 2 0 2 0 3
Asp 4 5 2 4 7 3 3 3
Glu 4 1 6 3 0 7 4 4
Lys 3 4 2 8 1 1 3 2
Arg 6 1 0 6 0 0 0 1
His 4 1 0 5 4 4 4 5