$VAR1 = undef;

Summary for peptidase M05.001: mycolysin

Names
MEROPS Name	mycolysin
Other names	neutral endopeptidase (Streptomyces cacaoi)

Domain architecture

MEROPS Classification
Classification	Clan MA >> Subclan MA(E) >> Family M5 >> Subfamily (none) >> M05.001
Holotype	mycolysin (Streptomyces cacaoi), Uniprot accession P20910 (peptidase unit: 206-550), MERNUM MER0001049
History	Identifier created: Handbook of Proteolytic Enzymes (1998) Academic Press, London.

Activity
Catalytic type	Metallo
Peplist	Included in the Peplist with identifier PL00149
NC-IUBMB	Subclass 3.4 (Peptidases) >> Sub-subclass 3.4.24 (Metalloendopeptidases) >> Peptidase 3.4.24.31
Enzymology	BRENDA database
Physiology	Bacterial nutrition.
Cleavage site specificity	Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern	-/-/-/fglfv/-/-/- (based on 12 cleavages)

Specificity matrix

Amino acid	P4	P3	P2	P1	P1'	P2'	P3'	P4'
Gly	1	2	1	3	0	0	2	1
Pro	0	0	0	0	0	0	1	1
Ala	1	1	0	1	0	0	0	1
Val	1	1	0	0	2	2	0	1
Leu	1	1	1	1	5	1	1	0
Ile	0	0	0	0	0	0	0	0
Met	0	0	0	0	0	0	0	0
Phe	0	0	1	4	3	1	0	0
Tyr	0	0	1	1	1	2	1	0
Trp	0	0	0	0	1	0	0	0
Ser	0	0	1	0	0	0	0	1
Thr	0	0	0	0	0	1	1	1
Cys	0	0	0	0	0	0	0	0
Asn	0	1	0	0	0	1	0	0
Gln	0	0	1	0	0	0	1	0
Asp	0	0	0	0	0	0	0	0
Glu	2	1	1	0	0	0	1	1
Lys	0	0	0	0	0	0	0	1
Arg	1	1	1	0	0	0	0	0
His	0	0	0	2	0	0	0	1