$VAR1 = undef;

Summary for peptidase C56.002: DJ-1 putative peptidase

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

 

Names
MEROPS NameDJ-1 putative peptidase
Other namescontraception-associated protein 1 (Rattus norvegicus), CAP1 (Rattus norvegicus), oncoprotein DJ-1, PARK7, RS protein (Homo sapiens), DJ-1
Domain architecture
MEROPS Classification
Classification Clan PC >> Subclan PC(C) >> Family C56 >> Subfamily (none) >> C56.002
HolotypeDJ-1 putative peptidase (Rattus norvegicus), Uniprot accession O88767 (peptidase unit: 30-147), MERNUM MER0010992
History Identifier created: MEROPS 5.4 (23 March 2001)
Activity
Catalytic typeCysteine
NC-IUBMBNot yet included in IUBMB recommendations.
Activity statushuman: putative
mouse: putative
Pharmaceutical relevancePARK7, an autosomal recessive form of early-onset parkinsonism caused by mutations in the DJ-1 gene
Pathways KEGGParkinson's disease
Other databases TREEFAMhttp://www.treefam.org/family/TF300119
Human genetics
Gene symbol Locus Megabases Ensembl Entrez gene Gene Cards OMIM
PARK7 1p36.2-p36.3 ENSG00000116288 11315 PARK7 602533
Mouse genetics
Gene symbol Position Megabases Ensembl Entrez gene MGI
Park7 4:E1 ENSMUSG00000028964 57320 MGI:2135637