$VAR1 = undef;
Summary for peptidase C53.001: pestivirus Npro peptidase
| Names | |
|---|---|
| MEROPS Name | pestivirus Npro peptidase |
| Other names | autoprotease p20, autoprotease p23, border disease virus (BDV) Npro endopeptidase, bovine viral diarrhea virus (BVDV) Npro endopeptidase, classical swine fever virus (CSFV) Npro endopeptidase, hog cholera virus Npro endopeptidase, N-terminal protease, pestivirus leader protease |
| Domain architecture |
|---|
| MEROPS Classification | |
|---|---|
| Classification | Clan CQ >> Subclan (none) >> Family C53 >> Subfamily (none) >> C53.001 |
| Holotype | pestivirus Npro peptidase (classical swine fever virus), Uniprot accession P19712 (peptidase unit: 1-168), MERNUM MER0002219 |
| History | Identifier created: MEROPS 5.3 (4 December 2000) |
| Activity | |||
|---|---|---|---|
| Catalytic type | Cysteine | ||
| NC-IUBMB | Not yet included in IUBMB recommendations. | ||
| Proteolytic events | CutDB database (1 cleavage) | ||
| Physiology | Pestiviruses are the only members of the Flaviviridae that encode a nonstructural protease at the N terminus of their polyproteins. This N-terminal protease (Npro) cleaves itself from the nascent polyprotein autocatalytically and thereby generates the N terminus of the adjacent viral capsid protein C (Rumenapf et al., 1998). | ||
