$VAR1 = undef;

Summary for peptidase C50.002: separase (Homo sapiens-type)

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Literature Substrates

 

Names
MEROPS Nameseparase (Homo sapiens-type)
Other namesESPL1 g.p. (Homo sapiens), extra spindle pole bodies like 1, ESPL1
Domain architecture
MEROPS Classification
Classification Clan CD >> Subclan (none) >> Family C50 >> Subfamily (none) >> C50.002
Holotypeseparase (Homo sapiens-type), Uniprot accession Q14674 (peptidase unit: 1612-2120), MERNUM MER0011775
History Identifier created: MEROPS 8.2 (4 August 2008)
Activity
Catalytic typeCysteine
NC-IUBMBNot yet included in IUBMB recommendations.
Pathways KEGGCell cycle
KEGGOocyte meiosis
Other databases TREEFAMhttp://www.treefam.org/family/TF101169
Human genetics
Gene symbol Locus Megabases Ensembl Entrez gene Gene Cards OMIM
ESPL1 8 ENSG00000135476 9700 ESPL1
Mouse genetics
Gene symbol Position Megabases Ensembl Entrez gene MGI
Espl1 15 ENSMUSG00000058290 105988 MGI:2146156