$VAR1 = undef;

Summary for peptidase C48.002: SENP1 peptidase

Names
MEROPS Name	SENP1 peptidase
Other names	Axam protein, Axin-associating molecule, sentrin-specific peptidase 1, SUMO-1 peptidase, SuPr-1

Domain architecture

MEROPS Classification
Classification	Clan CE >> Subclan (none) >> Family C48 >> Subfamily (none) >> C48.002
Holotype	SENP1 peptidase (Homo sapiens), Uniprot accession Q9P0U3 (peptidase unit: 456-614), MERNUM MER0011012
History	Identifier created: MEROPS 5.0 (17 April 2000)

Activity
Catalytic type	Cysteine
NC-IUBMB	Not yet included in IUBMB recommendations.
Proteolytic events	CutDB database (1 cleavage)
Activity status	human: active (Gong et al., 2000) mouse: active (Gong et al., 2000)
Other databases	TREEFAM	http://www.treefam.org/family/TF316289
Cleavage site specificity	Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern	Q/T/G/GK/-/E/p (based on 32 cleavages)

Specificity matrix

Amino acid	P4	P3	P2	P1	P1'	P2'	P3'	P4'
Gly	0	0	32	32	0	0	0	0
Pro	0	0	0	0	0	1	0	7
Ala	0	0	0	0	0	0	2	0
Val	0	0	0	0	2	2	0	2
Leu	0	0	0	0	0	3	0	0
Ile	0	0	0	0	0	3	1	1
Met	0	0	0	0	0	1	0	1
Phe	0	0	0	0	0	1	1	0
Tyr	0	3	0	0	0	1	0	2
Trp	0	0	0	0	0	0	0	0
Ser	0	0	0	0	1	2	1	1
Thr	0	29	0	0	0	2	1	0
Cys	0	0	0	0	0	0	0	0
Asn	0	0	0	0	0	0	1	1
Gln	32	0	0	0	0	4	1	4
Asp	0	0	0	0	0	0	1	2
Glu	0	0	0	0	0	3	15	2
Lys	0	0	0	0	23	3	0	1
Arg	0	0	0	0	0	0	0	0
His	0	0	0	0	1	0	0	0