$VAR1 = undef;

Summary for peptidase C14.043: metacaspase Ld (Leishmania-type)

Names
MEROPS Name	metacaspase Ld (Leishmania-type)
Other names	LdMC1, LdMC2, LmjMCA, TbMCA5 (Trypanosoma brucei)

Domain architecture

MEROPS Classification
Classification	Clan CD >> Subclan (none) >> Family C14 >> Subfamily B >> C14.043
Holotype	metacaspase Ld (Leishmania-type) (Leishmania donovani) (peptidase unit: 27-316), MERNUM MER0071798
History	Identifier created: MEROPS 8.0 (8 January 2008)

Activity
Catalytic type	Cysteine
NC-IUBMB	Not yet included in IUBMB recommendations.
Cleavage site specificity	Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern	gkn/dgkr/vgl/Rpv/gqlm/vdlf/pvgi (based on 27 cleavages)

Specificity matrix

Amino acid	P4	P3	P2	P1	P1'	P2'	P3'	P4'
Gly	7	6	6	0	2	5	0	3
Pro	0	0	2	0	5	0	0	5
Ala	0	3	0	0	3	2	0	0
Val	2	0	9	0	4	0	6	5
Leu	0	0	4	0	2	3	5	0
Ile	0	0	0	0	0	0	1	3
Met	0	0	1	0	0	3	0	0
Phe	0	0	1	0	0	0	3	0
Tyr	0	0	0	0	0	0	0	0
Trp	0	0	0	0	0	0	0	0
Ser	1	0	0	0	1	0	0	0
Thr	2	0	1	0	1	0	0	0
Cys	0	0	0	0	0	2	0	0
Asn	5	2	0	0	2	0	0	2
Gln	0	0	0	0	0	5	0	0
Asp	0	6	0	0	0	0	5	0
Glu	0	0	0	0	0	0	0	0
Lys	5	5	1	1	0	0	0	0
Arg	0	5	2	26	0	0	0	2
His	0	0	0	0	0	0	0	0