$VAR1 = undef;

Summary for peptidase A02.010: mouse mammary tumor virus retropepsin

Names
MEROPS Name	mouse mammary tumor virus retropepsin
Other names	retropepsin (mouse mammary tumor virus)

Domain architecture

MEROPS Classification
Classification	Clan AA >> Subclan (none) >> Family A2 >> Subfamily A >> A02.010
Holotype	mouse mammary tumor virus retropepsin, Uniprot accession P10271 (peptidase unit: 165-266), MERNUM MER0000970
History	Identifier created: Handbook of Proteolytic Enzymes (1998) Academic Press, London.

Activity
Catalytic type	Aspartic
NC-IUBMB	Not yet included in IUBMB recommendations.
Proteolytic events	CutDB database (2 cleavages)
Physiology	Processing of viral polyprotein.
Cleavage site specificity	Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern	S/qfkl/N/yflmP/I/V/Q (based on 13 cleavages)

Specificity matrix

Amino acid	P4	P3	P2	P1	P1'	P2'	P3'	P4'
Gly	0	0	0	0	0	0	0	0
Pro	0	0	0	0	12	0	0	0
Ala	0	0	1	0	0	1	0	0
Val	0	1	0	0	0	2	11	0
Leu	0	2	0	2	1	0	0	0
Ile	0	0	1	0	0	10	0	0
Met	0	0	0	2	0	0	0	0
Phe	0	2	0	3	0	0	0	1
Tyr	0	0	0	6	0	0	0	0
Trp	0	0	0	0	0	0	0	0
Ser	11	0	0	0	0	0	0	0
Thr	1	0	1	0	0	0	1	0
Cys	0	0	0	0	0	0	0	0
Asn	0	0	10	0	0	0	0	0
Gln	0	6	0	0	0	0	0	10
Asp	0	0	0	0	0	0	0	1
Glu	1	0	0	0	0	0	0	0
Lys	0	2	0	0	0	0	1	0
Arg	0	0	0	0	0	0	0	1
His	0	0	0	0	0	0	0	0