$VAR1 = undef;
Summary for peptidase A01.053: necepsin-1
| Names | |
|---|---|
| MEROPS Name | necepsin-1 |
| Other names | asp-1 g.p. (Caenorhabditis elegans), Mername-AA046 peptidase, Na-APR-2 g.p. (Necator americanus), nemepsin-3, Sc-ASP110 (Steinernema carpocapsae), Sc-ASP155 (Steinernema carpocapsae) |
| Domain architecture |
|---|
| MEROPS Classification | |
|---|---|
| Classification | Clan AA >> Subclan (none) >> Family A1 >> Subfamily A >> A01.053 |
| Holotype | necepsin-1 (Caenorhabditis elegans) (peptidase unit: 54-391), MERNUM MER0004851 |
| History | Identifier created: MEROPS 5.3 (4 December 2000) |
| Activity | |||
|---|---|---|---|
| Catalytic type | Aspartic | ||
| NC-IUBMB | Not yet included in IUBMB recommendations. | ||
| Proteolytic events | CutDB database (78 cleavages) | ||
| Physiology | In Caenorhabditis elegans, the asp-1 gene is exclusively transcribed in the intestinal cells, with the highest levels of expression observed at late embryonic and early larval stages of development. Transcription is not observed in the adult nematodes or mature larvae (Tcherepanova et al., 2000). | ||
| Other databases | PANTHER | http://www.pantherdb.org/panther/familyList.do?searchType=basic&fieldName=all&listType=6&fieldValue=PTHR13683:SF244 | |
| Cleavage site specificity | Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here. | ||
| Cleavage pattern | -/-/-/- -/-/-/- (based on 133 cleavages) | ||
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| Specificity matrix | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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