Structure of divisome complex FtsWIQLB
Yang L, Chen Y, Chang S, Shen C, Wang X, Zhang C, Zhang Z, Ding BS, Su Z, Dong H, Tang X
Cell Discov (2024) 10 pp. 2-2 [ Pubmed: 38172099 DOI: doi:10.1038/s41421-023-00629-w ]
- Cell division protein ftsb (10 kDa, Protein from Escherichia coli K-12)
- Cell division protein ftsl (11 kDa, Protein from Escherichia coli K-12)
- Peptidoglycan d,d-transpeptidase ftsi (62 kDa, Protein from Escherichia coli K-12)
- Probable peptidoglycan glycosyltransferase ftsw (43 kDa, Protein from Escherichia coli K-12)
- Cell division protein ftsq (32 kDa, Protein from Escherichia coli K-12)
- Divisome complex ftswiqlb (Complex from Escherichia coli K-12)
Cryo-EM Structure of OmpC3-MlaA Complex in MSP2N2 Nanodiscs
Resolution: 2.93 Å
EM Method: Single-particle
Fitted PDBs: 8i8r
Q-score: 0.477
Nat Commun (2023) 14 pp. 8285-8285 [ DOI: doi:10.1038/s41467-023-44144-8 Pubmed: 38092770 ]
- Outer membrane porin c (Complex from Escherichia coli)
- (2~{r},4~{r},5~{r},6~{r})-6-[(1~{r})-1,2-bis(oxidanyl)ethyl]-2-[(2~{r},4~{r},5~{r},6~{r})-6-[(1~{r})-1,2-bis(oxidanyl)ethyl]-2-carboxy-2-[[(2~{r},3~{s},4~{r},5~{r},6~{r})-5-[[(3~{r})-3-dodecanoyloxytetradecanoyl]amino]-6-[[(2~{r},3~{s},4~{r},5~{r},6~{r})-3-oxidanyl-5-[[(3~{r})-3-oxidanyltetradecanoyl]amino]-4-[(3~{r})-3-oxidanyltetradecanoyl]oxy-6-phosphonooxy-oxan-2-yl]methoxy]-3-phosphonooxy-4-[(3~{r})-3-tetradecanoyloxytetradecanoyl]oxy-oxan-2-yl]methoxy]-5-oxidanyl-oxan-4-yl]oxy-4,5-bis(oxidanyl)oxane-2-carboxylic acid (2 kDa, Ligand)
- Outer membrane complex of ompc-mlaa with periplasmic mlac reconstituted in msp2n2 nanodiscs (28 kDa, Complex from Escherichia coli)
- Intermembrane phospholipid transport system lipoprotein mlaa (26 kDa, Protein from Escherichia coli K-12)
- Outer membrane porin c (38 kDa, Protein from Escherichia coli K-12)
- Intermembrane phospholipid transport system lipoprotein mlaa (Complex)
Cryo-EM Structure of OmpC3-MlaA-MlaC Complex in MSP2N2 Nanodiscs
Resolution: 3.25 Å
EM Method: Single-particle
Fitted PDBs: 8i8x
Q-score: 0.421
Nat Commun (2023) 14 pp. 8285-8285 [ DOI: doi:10.1038/s41467-023-44144-8 Pubmed: 38092770 ]
- Outer membrane porin c (Complex from Escherichia coli)
- (2~{r},4~{r},5~{r},6~{r})-6-[(1~{r})-1,2-bis(oxidanyl)ethyl]-2-[(2~{r},4~{r},5~{r},6~{r})-6-[(1~{r})-1,2-bis(oxidanyl)ethyl]-2-carboxy-2-[[(2~{r},3~{s},4~{r},5~{r},6~{r})-5-[[(3~{r})-3-dodecanoyloxytetradecanoyl]amino]-6-[[(2~{r},3~{s},4~{r},5~{r},6~{r})-3-oxidanyl-5-[[(3~{r})-3-oxidanyltetradecanoyl]amino]-4-[(3~{r})-3-oxidanyltetradecanoyl]oxy-6-phosphonooxy-oxan-2-yl]methoxy]-3-phosphonooxy-4-[(3~{r})-3-tetradecanoyloxytetradecanoyl]oxy-oxan-2-yl]methoxy]-5-oxidanyl-oxan-4-yl]oxy-4,5-bis(oxidanyl)oxane-2-carboxylic acid (2 kDa, Ligand)
- Intermembrane phospholipid transport system lipoprotein mlaa (26 kDa, Protein from Escherichia coli K-12)
- Intermembrane phospholipid transport system binding protein mlac (22 kDa, Protein from Escherichia coli K-12)
- Outer membrane porin c (38 kDa, Protein from Escherichia coli K-12)
- Ompc3-mlaa complex in msp2n2 nanodiscs disulfide-bonded to mlac (52 kDa, Complex from Escherichia coli)
- Complex of mlaa disulfide trapped with mlac (Complex from Escherichia coli)
Cell divisome sPG hydrolysis machinery FtsEX-EnvC
Resolution: 3.11 Å
EM Method: Single-particle
Fitted PDBs: 8hd0
Q-score: 0.385
To Be Published
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Cell division protein ftsx (38 kDa, Protein from Escherichia coli (strain K12))
- Murein hydrolase activator envc (46 kDa, Protein from Escherichia coli (strain K12))
- Bacterial divisom spg hydrolysis machinery ftsex-envc (126 kDa, Complex from Escherichia coli)
- Cell division atp-binding protein ftse (24 kDa, Protein from Escherichia coli (strain K12))
Structure of TolQR complex from E.coli
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 8odt
Q-score: 0.198
Williams-Jones DP, Webby MN, Press CE, Gradon JM, Armstrong SR, Szczepaniak J, Kleanthous C
PNAS (2023) 120 pp. e2306707120-e2306707120 [ DOI: doi:10.1073/pnas.2306707120 Pubmed: 37972066 ]
- Tolq-tolr 5:2 complex (170 kDa, Complex from Escherichia coli)
- Tol-pal system protein tolq (25 kDa, Protein from Escherichia coli K-12)
- Tol-pal system protein tolr (20 kDa, Protein from Escherichia coli K-12)
Cryo-EM structure of biparatopic antibody Bp109-92 in complex with TNFR2
Resolution: 3.63 Å
EM Method: Single-particle
Fitted PDBs: 8hlb
Q-score: 0.446
Akiba H, Fujita J, Ise T, Nishiyama K, Miyata T, Kato T, Namba K, Ohno H, Kamada H, Nagata S, Tsumoto K
Commun Biol (2023) 6 pp. 987-987 [ Pubmed: 37758868 DOI: doi:10.1038/s42003-023-05326-8 ]
- Tr92 heavy chain (25 kDa, Protein from Homo sapiens)
- Tr109 heavy chain (25 kDa, Protein from Homo sapiens)
- Cryo-em structure of biparatopic antibody bp109-92 in complex with tnfr2 (Complex from Homo sapiens)
- Tumor necrosis factor receptor superfamily member 1b,maltose/maltodextrin-binding periplasmic protein (60 kDa, Protein from Escherichia coli (strain K12))
- Tr92 light chain (23 kDa, Protein from Homo sapiens)
- Tr109 light chain (23 kDa, Protein from Homo sapiens)
Cryo-EM structure of Escherichia coli cytochrome bo3 in DDM detergent
Resolution: 3.09 Å
EM Method: Single-particle
Fitted PDBs: 8go3
Q-score: 0.553
To Be Published
- Protoporphyrin ix containing fe (616 Da, Ligand)
- Ubiquinone-8 (727 Da, Ligand)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Cytochrome bo(3) ubiquinol oxidase subunit 1 (74 kDa, Protein from Escherichia coli K-12)
- Ubiquinol oxidase (22 kDa, Protein from Escherichia coli K-12)
- Heme o (838 Da, Ligand)
- Purified escherichia coli cytochrome bo3 (Complex from Escherichia coli K-12)
- Copper (ii) ion (63 Da, Ligand)
- Cytochrome bo(3) ubiquinol oxidase subunit 2 (34 kDa, Protein from Escherichia coli K-12)
- Cytochrome bo(3) ubiquinol oxidase subunit 4 (12 kDa, Protein from Escherichia coli K-12)
YES Complex - E. coli MraY, Protein E ID21, E. coli SlyD
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8g01
Q-score: 0.338
Orta AK, Riera N, Li YE, Tanaka S, Yun HG, Klaic L, Clemons Jr WM
Science (2023) 381 pp. eadg9091-eadg9091 [ Pubmed: 37440661 DOI: doi:10.1126/science.adg9091 ]
- Slyd (20 kDa, Complex from Escherichia coli K-12)
- Yes complex (140 kDa, Complex)
- Phospho-n-acetylmuramoyl-pentapeptide-transferase (39 kDa, Protein from Escherichia coli K-12)
- Lysis protein e (8 kDa, Complex from Escherichia phage ID21)
- Fkbp-type peptidyl-prolyl cis-trans isomerase slyd (16 kDa, Protein from Escherichia coli K-12)
- Dimeric structure of mray (39 kDa, Complex from Escherichia coli K-12)
- Gpe (9 kDa, Protein from Escherichia phage ID21)
YES Complex - E. coli MraY, Protein E ID21, E. coli SlyD
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 8g02
Q-score: 0.304
Orta AK, Riera N, Li YE, Tanaka S, Yun HG, Klaic L, Clemons Jr WM
Science (2023) 381 pp. eadg9091-eadg9091 [ Pubmed: 37440661 DOI: doi:10.1126/science.adg9091 ]
- Lysis protein e (11 kDa, Complex from Escherichia phage phiX174)
- Slyd (20 kDa, Complex from Escherichia coli K-12)
- Yes complex (140 kDa, Complex)
- Phospho-n-acetylmuramoyl-pentapeptide-transferase (39 kDa, Protein from Escherichia coli K-12)
- Lysis protein e (11 kDa, Protein from Escherichia phage phiX174)
- Peptidyl-prolyl cis-trans isomerase (16 kDa, Protein from Escherichia coli K-12)
- Dimeric structure of mray (39 kDa, Complex from Escherichia coli K-12)
Molecular mechanism of nucleotide inhibition of human uncoupling protein 1
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 8g8w
Q-score: 0.465
Jones SA, Gogoi P, Ruprecht JJ, King MS, Lee Y, Zogg T, Pardon E, Chand D, Steimle S, Copeman DM, Cotrim CA, Steyaert J, Crichton PG, Moiseenkova-Bell V, Kunji ERS
Sci Adv (2023) 9 pp. eadh4251-eadh4251 [ DOI: doi:10.1126/sciadv.adh4251 Pubmed: 37256948 ]
- Pro-macrobody 65, maltose/maltodextrin-binding periplasmic protein chimera (54 kDa, Protein from Escherichia coli (strain K12))
- Pro-macrobody 71, maltose/maltodextrin-binding periplasmic protein chimera (53 kDa, Protein from Escherichia coli (strain K12))
- Cardiolipin (1 kDa, Ligand)
- Complex of human uncoupling protein 1 with two promacrobodies (Complex from Homo sapiens)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Mitochondrial brown fat uncoupling protein 1 (33 kDa, Protein from Homo sapiens)