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EMD-29857
Molecular mechanism of nucleotide inhibition of human uncoupling protein 1
EMD-29857
Single-particle3.8 Å
Deposition: 20/02/2023Map released: 07/06/2023
Last modified: 06/11/2024
Sample Organism:
Homo sapiens,
Escherichia coli (strain K12)
Sample: Complex of human uncoupling protein 1 with two promacrobodies
Fitted models: 8g8w
Deposition Authors: Gogoi P
,
Jones SA
,
Ruprecht JJ
,
King MS
,
Lee Y
,
Zogg T
,
Pardon E
,
Chand D
,
Steimle S
,
Copeman D,
Cotrim CA
,
Steyaert J
,
Crichton PG
,
Moiseenkova-Bell V,
Kunji ERS
Sample: Complex of human uncoupling protein 1 with two promacrobodies
Fitted models: 8g8w
Deposition Authors: Gogoi P
,
Jones SA
,
Ruprecht JJ
,
King MS
,
Lee Y
,
Zogg T
,
Pardon E
,
Chand D
,
Steimle S
,
Copeman D,
Cotrim CA
,
Steyaert J
,
Crichton PG
,
Moiseenkova-Bell V,
Kunji ERS
Structural basis of purine nucleotide inhibition of human uncoupling protein 1.
Jones SA
,
Gogoi P
,
Ruprecht JJ
,
King MS
,
Lee Y
,
Zogg T
,
Pardon E
,
Chand D
,
Steimle S
,
Copeman DM
,
Cotrim CA
,
Steyaert J
,
Crichton PG
,
Moiseenkova-Bell V,
Kunji ERS
(2023) Sci Adv , 9 , eadh4251 - eadh4251
,
Gogoi P
,
Ruprecht JJ
,
King MS
,
Lee Y
,
Zogg T
,
Pardon E
,
Chand D
,
Steimle S
,
Copeman DM
,
Cotrim CA
,
Steyaert J
,
Crichton PG
,
Moiseenkova-Bell V,
Kunji ERS
(2023) Sci Adv , 9 , eadh4251 - eadh4251
Grant Support:
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): GM144120 (United States)
- Medical Research Council (MRC, United Kingdom): MC_UU_00028/2 (United Kingdom)
- Medical Research Council (MRC, United Kingdom): MC_UU_00015/1 (United Kingdom)
- Biotechnology and Biological Sciences Research Council (BBSRC): BB/S00940X/1 (United Kingdom)
- European Union (EU): Instruct-ERIC/ESFRI (European Union)
- Research Foundation - Flanders (FWO): (Belgium)
