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L5A7 Fab bound to Indonesia2005 Hemagglutinin
Olia AS, Prabhakaran M, McDermott AB, Kwong PD
To Be Published
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- L5a7 fab heavy chain (24 kDa, Protein from Homo sapiens)
- L5a7 fab light chain (22 kDa, Protein from Homo sapiens)
- Complex of l5a7 fab and indonesia2005 ha (Complex from Homo sapiens)
- Hemagglutinin ha2 chain (19 kDa, Protein from Influenza A virus)
- Hemagglutinin ha1 chain (36 kDa, Protein from Influenza A virus)
S1V2-72 Fab bound to EHA2 from influenza B/Malaysia/2506/2004
Resolution: 4.98 Å
EM Method: Single-particle
Fitted PDBs: 8udg
Q-score: 0.202
Finney J, Moseman AP, Kong S, Watanabe A, Song S, Walsh Jr RM, Kuraoka M, Kotaki R, Moseman EA, McCarthy KR, Liao D, Liang X, Nie X, Lavidor O, Abbott R, Harrison SC, Kelsoe G
PNAS (2024) 121 pp. e2316964120-e2316964120 [ Pubmed: 38147556 DOI: doi:10.1073/pnas.2316964120 ]
- S1v2-72 heavy chain (24 kDa, Protein from Homo sapiens)
- S1v2-72 light chain (22 kDa, Protein from Homo sapiens)
- Complex of two s1v2-72 fabs with postfusion ha2 (Complex from Influenza B virus (B/Malaysia/2506/2004))
- Hemagglutinin (17 kDa, Protein from Influenza B virus (B/Malaysia/2506/2004))
Resolution: 3.96 Å
EM Method: Single-particle
Fitted PDBs: 8d21
Q-score: 0.395
Andrews SF, Cominsky LY, Shimberg GD, Gillespie RA, Gorman J, Raab JE, Brand J, Creanga A, Gajjala SR, Narpala S, Cheung CSF, Harris DR, Zhou T, Gordon I, Holman L, Mendoza F, Houser KV, Chen GL, Mascola JR, Graham BS, Kwong PD, Widge A, Dropulic LK, Ledgerwood JE, Kanekiyo M, McDermott AB
Sci Transl Med (2023) 15 pp. eade4976-eade4976 [ DOI: doi:10.1126/scitranslmed.ade4976 Pubmed: 37075126 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- 1b06 fab with nc99 ha trimer (Complex from Influenza A virus)
- Hemagglutinin ha1 chain (36 kDa, Protein from Influenza A virus)
- 1b06 light chain (11 kDa, Protein from Homo sapiens)
- Cryo-em structure of the vrc321 clinical trial, vaccine-elicited, human antibody 1b06 in complex with a stabilized nc99 ha trimer (Complex)
- 1b06 heavy chain (13 kDa, Protein from Homo sapiens)
- Hemagglutinin ha2 chain (25 kDa, Protein from Influenza A virus)
Cryo-EM structure of the canine distemper virus tetrameric attachment glycoprotein
Resolution: 3.26 Å
EM Method: Single-particle
Fitted PDBs: 7zny
Q-score: 0.425
Kalbermatter D, Jeckelmann JM, Wyss M, Shrestha N, Pliatsika D, Riedl R, Lemmin T, Plattet P, Fotiadis D
PNAS (2023) 120 pp. e2208866120-e2208866120 [ Pubmed: 36716368 DOI: doi:10.1073/pnas.2208866120 ]
- Canine morbillivirus (272 kDa, Virus from Canine morbillivirus)
- Hemagglutinin glycoprotein (68 kDa, Protein from Canine morbillivirus)
Resolution: 3.14 Å
EM Method: Single-particle
Fitted PDBs: 7yhk
Q-score: 0.556
Li T, Chen J, Zheng Q, Xue W, Zhang L, Rong R, Zhang S, Wang Q, Hong M, Zhang Y, Cui L, He M, Lu Z, Zhang Z, Chi X, Li J, Huang Y, Wang H, Tang J, Ying D, Zhou L, Wang Y, Yu H, Zhang J, Gu Y, Chen Y, Li S, Xia N
Nat Commun (2022) 13 pp. 5182-5182 [ Pubmed: 36056024 DOI: doi:10.1038/s41467-022-32926-5 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Ha trimer of a/beijing/262/1995(h1n1) (Complex from Influenza A virus (A/Beijing/262/1995(H1N1)))
- 12h5 light chain (12 kDa, Protein from Mus musculus)
- Neutralizing antibody 12h5 (Complex from Mus musculus)
- Hemagglutinin (62 kDa, Protein from Influenza A virus (A/Beijing/262/1995(H1N1)))
- Cryo-em structure of the ha trimer of a/beijing/262/1995(h1n1) in complex with neutralizing antibody 12h5 (Complex)
- 12h5 heavy chain (12 kDa, Protein from Mus musculus)
Resolution: 2.85 Å
EM Method: Single-particle
Fitted PDBs: 7l0l
Q-score: 0.555
Andrews SF, Raab JE, Gorman J, Gillespie RA, Cheung CSF, Rawi R, Cominsky LY, Boyington JC, Creanga A, Shen CH, Harris DR, Olia AS, Nazzari AF, Zhou T, Houser KV, Chen GL, Mascola JR, Graham BS, Kanekiyo M, Ledgerwood JE, Kwong PD, McDermott AB
Nat Med (2022) 28 pp. 373-382 [ Pubmed: 35115707 DOI: doi:10.1038/s41591-021-01636-8 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- 316-310-1b11 light chain (23 kDa, Protein from Homo sapiens)
- Hemagglutinin ha1 chain (38 kDa, Protein from Influenza A virus (A/Canada/720/2005(H2N2)))
- 316-310-1b11 heavy chain (25 kDa, Protein from Homo sapiens)
- Hemagglutinin ha2 chain (25 kDa, Protein from Influenza A virus (A/Canada/720/2005(H2N2)))
- 316-310-1b11 fab in complex with an h2 can05 ha trimer (Complex from Influenza A virus)
Resolution: 2.76 Å
EM Method: Single-particle
Fitted PDBs: 6wxl
Q-score: 0.594
Cheung CS, Gorman J, Andrews SF, Rawi R, Reveiz M, Shen CH, Wang Y, Harris DR, Nazzari AF, Olia AS, Raab J, Teng IT, Verardi R, Wang S, Yang Y, Chuang GY, McDermott AB, Zhou T, Kwong PD
Structure (2022) [ Pubmed: 35489332 DOI: doi:10.1016/j.str.2022.04.003 ]
- 1d12 in complex with an h7 sh13 ha trimer (Complex)
- Hemagglutinin ha1 chain (35 kDa, Protein from Influenza A virus (A/Shanghai/JS01/2013(H7N9)))
- 1d12 light chain (23 kDa, Protein from Homo sapiens)
- 1d21 heavy chain (25 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- H7 sh13 ha trimer (Complex from Influenza A virus)
- 1d12 fab (Complex from Homo sapiens)
- Hemagglutinin ha2 chain (25 kDa, Protein from Influenza A virus (A/Shanghai/JS01/2013(H7N9)))
CryoEM structure of influenza hemagglutinin A/Victoria/361/2011 in complex with cyno antibody 3B10
Resolution: 4.7 Å
EM Method: Single-particle
Fitted PDBs: 6wzt
Q-score: 0.315
Darricarrere N, Qiu Y, Kanekiyo M, Creanga A, Gillespie RA, Moin SM, Saleh J, Sancho J, Chou TH, Zhou Y, Zhang R, Dai S, Moody A, Saunders KO, Crank MC, Mascola JR, Graham BS, Wei CJ, Nabel GJ
Sci Transl Med (2021) 13 [ Pubmed: 33658355 DOI: doi:10.1126/scitranslmed.abe5449 ]
- Cyno antibody light chain (23 kDa, Protein from Macaca fascicularis)
- Cyno antibody heavy chain (24 kDa, Protein from Macaca fascicularis)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Hemagglutinin (56 kDa, Protein from Influenza A virus)
- Influenza hemagglutinin a/victoria/361/2011 in complex with 3b10 fab (336 kDa, Complex from Influenza A virus)
- Cyno antibody (Complex)
- Hemagglutinin (Complex from Macaca fascicularis)