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Resolution: 3.96 Å
EM Method: Single-particle
Fitted PDBs: 8d21
Q-score: 0.395
Andrews SF, Cominsky LY, Shimberg GD, Gillespie RA, Gorman J, Raab JE, Brand J, Creanga A, Gajjala SR, Narpala S, Cheung CSF, Harris DR, Zhou T, Gordon I, Holman L, Mendoza F, Houser KV, Chen GL, Mascola JR, Graham BS, Kwong PD, Widge A, Dropulic LK, Ledgerwood JE, Kanekiyo M, McDermott AB
Sci Transl Med (2023) 15 pp. eade4976-eade4976 [ DOI: doi:10.1126/scitranslmed.ade4976 Pubmed: 37075126 ]
- 1b06 light chain (11 kDa, Protein from Homo sapiens)
- Cryo-em structure of the vrc321 clinical trial, vaccine-elicited, human antibody 1b06 in complex with a stabilized nc99 ha trimer (Complex)
- 1b06 heavy chain (13 kDa, Protein from Homo sapiens)
- Hemagglutinin ha2 chain (25 kDa, Protein from Influenza A virus)
- 1b06 fab with nc99 ha trimer (Complex from Influenza A virus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Hemagglutinin ha1 chain (36 kDa, Protein from Influenza A virus)
Resolution: 2.85 Å
EM Method: Single-particle
Fitted PDBs: 7l0l
Q-score: 0.555
Andrews SF, Raab JE, Gorman J, Gillespie RA, Cheung CSF, Rawi R, Cominsky LY, Boyington JC, Creanga A, Shen CH, Harris DR, Olia AS, Nazzari AF, Zhou T, Houser KV, Chen GL, Mascola JR, Graham BS, Kanekiyo M, Ledgerwood JE, Kwong PD, McDermott AB
Nat Med (2022) 28 pp. 373-382 [ DOI: doi:10.1038/s41591-021-01636-8 Pubmed: 35115707 ]
- Hemagglutinin ha1 chain (38 kDa, Protein from Influenza A virus (A/Canada/720/2005(H2N2)))
- 316-310-1b11 fab in complex with an h2 can05 ha trimer (Complex from Influenza A virus)
- Hemagglutinin ha2 chain (25 kDa, Protein from Influenza A virus (A/Canada/720/2005(H2N2)))
- 316-310-1b11 heavy chain (25 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- 316-310-1b11 light chain (23 kDa, Protein from Homo sapiens)
CryoEM structure of influenza hemagglutinin A/Victoria/361/2011 in complex with cyno antibody 3B10
Resolution: 4.7 Å
EM Method: Single-particle
Fitted PDBs: 6wzt
Q-score: 0.315
Darricarrere N, Qiu Y, Kanekiyo M, Creanga A, Gillespie RA, Moin SM, Saleh J, Sancho J, Chou TH, Zhou Y, Zhang R, Dai S, Moody A, Saunders KO, Crank MC, Mascola JR, Graham BS, Wei CJ, Nabel GJ
Sci Transl Med (2021) 13 [ Pubmed: 33658355 DOI: doi:10.1126/scitranslmed.abe5449 ]
- Cyno antibody light chain (23 kDa, Protein from Macaca fascicularis)
- Cyno antibody (Complex)
- Cyno antibody heavy chain (24 kDa, Protein from Macaca fascicularis)
- Hemagglutinin (56 kDa, Protein from Influenza A virus)
- Influenza hemagglutinin a/victoria/361/2011 in complex with 3b10 fab (336 kDa, Complex from Influenza A virus)
- Hemagglutinin (Complex from Macaca fascicularis)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)