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natural_source_ncbi_code:"3052230"

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Current Database

  • EMDB [8]

Current status

  • REL [8]

Sample type

  • Complex [8]
  • Ligand [8]
  • Protein [8]
  • RNA [6]

Organism

  • Hepacivirus hominis [8]
  • Homo sapiens [6]

EM Method

  • Single-particle [8]

Resolution

  • ≥ 3Å and < 4Å [8]

Model molecular weight

  • 100-250 kDa [2]

Release Date

  • 2025 [6]
  • 2024 [2]

Author by name

  • Imami K [6]
  • Imataka H [6]
  • Ito T [6]
  • Iwasaki S [6]
  • Iwasaki W [6]
  • Kashiwagi K [6]
  • Machida K [6]
  • Matsumoto A [6]
  • Nishimoto M [6]
  • Sakamoto A [6]
  • Shichino Y [6]
  • Takahashi M [6]
  • Augestad EH [2]
  • Bukh J [2]
  • Fanalista M [2]
  • Gourdon P [2]
  • Groenberg C [2]
  • Gronberg C [2]
  • Holmboe Olesen C [2]
  • Olesen CH [2]
  • Prentoe J [2]
  • Soerensen A [2]
  • Velazquez-moctezuma R [2]
  • Wang K [2]

Author by ORCID

  • Holmboe Olesen C [2]
  • Wang K [2]
  • Bukh J [2]
  • Gourdon P [2]
  • Augestad EH [2]
  • Prentoe J [2]
  • Soerensen A [2]

Journal

  • PNAS [6]
  • NATURE [2]

Software

  • CRYOSPARC [2]

Microscope

  • TFS KRIOS [6]
  • FEI TITAN KRIOS [2]

Electron Source

  • FIELD EMISSION GUN [8]

Film or detector model

  • GATAN K3 6K X 4K [8]

External links

  • ChEBI [2]
  • ChEMBL [2]
  • Gene Ontology [2]
  • InterPro [2]
  • PDB [2]
  • PDBe-Kb [2]
  • Pfam [2]
  • UniProt [2]
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EMD-62386
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Structure of the human 40S ribosome complexed with HCV IRES and eIF3
Release date: Dec. 3, 2025
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 9kkf

Iwasaki W, Kashiwagi K, Sakamoto A, Nishimoto M, Takahashi M, Machida K, Imataka H, Matsumoto A, Shichino Y, Iwasaki S, Imami K, Ito T

PNAS (2025) [ DOI: doi:10.1073/pnas.2505538122 ]

EMD-62453
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Structure of the human 40S ribosome complexed with HCV IRES, eIF1A and eIF3
Release date: Dec. 3, 2025
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 9kn5

Iwasaki W, Kashiwagi K, Sakamoto A, Nishimoto M, Takahashi M, Machida K, Imataka H, Matsumoto A, Shichino Y, Iwasaki S, Imami K, Ito T

PNAS (2025) [ DOI: doi:10.1073/pnas.2505538122 ]

EMD-62454
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Structure of the HCV IRES-dependent pre-48S translation initiation complex with eIF1A, eIF5B, and eIF3
Release date: Dec. 3, 2025
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 9kn6

Iwasaki W, Kashiwagi K, Sakamoto A, Nishimoto M, Takahashi M, Machida K, Imataka H, Matsumoto A, Shichino Y, Iwasaki S, Imami K, Ito T

PNAS (2025) [ DOI: doi:10.1073/pnas.2505538122 ]

EMD-62535
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Structure of the HCV IRES-dependent 48S translation initiation complex with eIF5B and eIF3
Release date: Dec. 3, 2025
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 9krp

Iwasaki W, Kashiwagi K, Sakamoto A, Nishimoto M, Takahashi M, Machida K, Imataka H, Matsumoto A, Shichino Y, Iwasaki S, Imami K, Ito T

PNAS (2025) [ DOI: doi:10.1073/pnas.2505538122 ]

EMD-62671
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Cryo-EM structure of the HCV IRES-dependently initiated CMV-stalled 80S ribosome non-rotated state in complexed with eIF3
Release date: Dec. 3, 2025
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 9kzu

Iwasaki W, Kashiwagi K, Sakamoto A, Nishimoto M, Takahashi M, Machida K, Imataka H, Matsumoto A, Shichino Y, Iwasaki S, Imami K, Ito T

PNAS (2025) [ DOI: doi:10.1073/pnas.2505538122 ]

EMD-62679
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3D View
Cryo-EM structure of the HCV IRES-dependently initiated CMV-stalled 80S ribosome rotated state in complexed with eIF3
Release date: Dec. 3, 2025
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 9kzx

Iwasaki W, Kashiwagi K, Sakamoto A, Nishimoto M, Takahashi M, Machida K, Imataka H, Matsumoto A, Shichino Y, Iwasaki S, Imami K, Ito T

PNAS (2025) [ DOI: doi:10.1073/pnas.2505538122 ]

EMD-19243
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HCV E1/E2 homodimer complex
Release date: Sept. 4, 2024
Resolution: 3.55 Å
EM Method: Single-particle
Fitted PDBs: 8rjj
Q-score: 0.363

Augestad EH, Holmboe Olesen C, Gronberg C, Soerensen A, Velazquez-Moctezuma R, Fanalista M, Bukh J, Wang K, Gourdon P, Prentoe J

Nature (2024) 633 pp. 704-709 [ Pubmed: 39232163 DOI: doi:10.1038/s41586-024-07783-5 ]

EMD-19254
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HCV E1/E2 homodimer complex, ectodomain
Release date: Sept. 4, 2024
Resolution: 3.38 Å
EM Method: Single-particle
Fitted PDBs: 8rk0
Q-score: 0.366

Augestad EH, Holmboe Olesen C, Gronberg C, Soerensen A, Velazquez-Moctezuma R, Fanalista M, Bukh J, Wang K, Gourdon P, Prentoe J

Nature (2024) 633 pp. 704-709 [ Pubmed: 39232163 DOI: doi:10.1038/s41586-024-07783-5 ]

Sort by: Download
Showing 1 - 8 of 8. Page 1 of 1
Display:
Statistics
×

Download











































Preview first 10
Download

Filter By

Current Database

  • EMDB [8]

Current status

  • REL [8]

Sample type

  • Complex [8]
  • Ligand [8]
  • Protein [8]
  • RNA [6]

Organism

  • Hepacivirus hominis [8]
  • Homo sapiens [6]

EM Method

  • Single-particle [8]

Resolution

  • ≥ 3Å and < 4Å [8]

Model molecular weight

  • 100-250 kDa [2]

Release Date

  • 2025 [6]
  • 2024 [2]

Author by name

  • Imami K [6]
  • Imataka H [6]
  • Ito T [6]
  • Iwasaki S [6]
  • Iwasaki W [6]
  • Kashiwagi K [6]
  • Machida K [6]
  • Matsumoto A [6]
  • Nishimoto M [6]
  • Sakamoto A [6]
  • Shichino Y [6]
  • Takahashi M [6]
  • Augestad EH [2]
  • Bukh J [2]
  • Fanalista M [2]
  • Gourdon P [2]
  • Groenberg C [2]
  • Gronberg C [2]
  • Holmboe Olesen C [2]
  • Olesen CH [2]
  • Prentoe J [2]
  • Soerensen A [2]
  • Velazquez-moctezuma R [2]
  • Wang K [2]

Author by ORCID

  • Holmboe Olesen C [2]
  • Wang K [2]
  • Bukh J [2]
  • Gourdon P [2]
  • Augestad EH [2]
  • Prentoe J [2]
  • Soerensen A [2]

Journal

  • PNAS [6]
  • NATURE [2]

Software

  • CRYOSPARC [2]

Microscope

  • TFS KRIOS [6]
  • FEI TITAN KRIOS [2]

Electron Source

  • FIELD EMISSION GUN [8]

Film or detector model

  • GATAN K3 6K X 4K [8]

External links

  • ChEBI [2]
  • ChEMBL [2]
  • Gene Ontology [2]
  • InterPro [2]
  • PDB [2]
  • PDBe-Kb [2]
  • Pfam [2]
  • UniProt [2]