EMD-62454

Single-particle
3.3 Å
EMD-62454
3D View Gallery
Deposition: 18/11/2024
Map released: 03/12/2025
Last modified: 17/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-62454
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9kn6 summary report (pdf.gz) Map and 9kn6 FULL report (pdf.gz)
EMICSS annotations (xml)

Structure of the HCV IRES-dependent pre-48S translation initiation complex with eIF1A, eIF5B, and eIF3

EMD-62454

Single-particle
3.3 Å
EMD-62454
3D View Gallery
Deposition: 18/11/2024
Map released: 03/12/2025
Last modified: 17/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Hepacivirus hominis
Sample: HCV IRES-dependent pre-48S translation initiation complex with eIF1A, eIF5B, and eIF3
Fitted models: 9kn6

Deposition Authors: Iwasaki W, Kashiwagi K, Sakamoto A, Nishimoto M, Takahashi M, Machida K, Imataka H, Matsumoto A, Shichino Y, Iwasaki S, Imami K, Ito T
Structural insights into the role of eIF3 in translation mediated by the HCV IRES.
Iwasaki W, Kashiwagi K, Sakamoto A, Nishimoto M, Takahashi M, Machida K, Imataka H, Matsumoto A, Shichino Y, Iwasaki S, Imami K, Ito T
(2025) PNAS , 122 , e2505538122 - e2505538122
PUBMED: 41337487
DOI: doi:10.1073/pnas.2505538122
ISSN: 1091-6490
ASTM: PNASA6