EMD-62671
Cryo-EM structure of the HCV IRES-dependently initiated CMV-stalled 80S ribosome (non-rotated state) in complexed with eIF3
EMD-62671
Single-particle3.0 Å
Deposition: 11/12/2024Map released: 03/12/2025
Last modified: 17/12/2025
Sample Organism:
Homo sapiens,
Hepacivirus hominis
Sample: HCV IRES-dependently initiated CMV-stalled 80S ribosome (non-rotated state) in complexed with eIF3
Fitted models: 9kzu
Deposition Authors: Iwasaki W
,
Kashiwagi K ,
Sakamoto A ,
Nishimoto M,
Takahashi M,
Machida K ,
Imataka H,
Matsumoto A ,
Shichino Y ,
Iwasaki S ,
Imami K,
Ito T
Sample: HCV IRES-dependently initiated CMV-stalled 80S ribosome (non-rotated state) in complexed with eIF3
Fitted models: 9kzu
Deposition Authors: Iwasaki W
,
Kashiwagi K ,
Sakamoto A ,
Nishimoto M,
Takahashi M,
Machida K ,
Imataka H,
Matsumoto A ,
Shichino Y ,
Iwasaki S ,
Imami K,
Ito T
Structural insights into the role of eIF3 in translation mediated by the HCV IRES.
Iwasaki W ,
Kashiwagi K ,
Sakamoto A ,
Nishimoto M,
Takahashi M,
Machida K ,
Imataka H,
Matsumoto A ,
Shichino Y ,
Iwasaki S ,
Imami K,
Ito T
(2025) PNAS , 122 , e2505538122 - e2505538122
,
Kashiwagi K ,
Sakamoto A ,
Nishimoto M,
Takahashi M,
Machida K ,
Imataka H,
Matsumoto A ,
Shichino Y ,
Iwasaki S ,
Imami K,
Ito T
(2025) PNAS , 122 , e2505538122 - e2505538122
Grant Support: