Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

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grant_code:"ZDKJ2021028"

Filter By

Current Database

  • EMDB [29]

Current status

  • REL [29]

Sample type

  • Complex [29]
  • Protein [29]
  • Ligand [17]

Organism

  • Homo sapiens [29]
  • Bos taurus [14]
  • Synthetic construct [12]
  • Rattus norvegicus [3]
  • Oplophorus gracilirostris [2]
  • Lama glama [2]
  • Mus musculus [1]

EM Method

  • Single-particle [29]

Resolution

  • ≥ 2Å and < 3Å [16]
  • ≥ 3Å and < 4Å [13]

Model molecular weight

  • 100-250 kDa [29]

Release Date

  • 2025 [11]
  • 2024 [2]
  • 2023 [9]
  • 2022 [7]

Author by name

  • Wang MW [29]
  • Zhou Q [29]
  • Liu X [23]
  • Yang D [23]
  • Xu Y [15]
  • Chen Y [14]
  • Wang M-W [13]
  • Zhao FH [11]
  • Zhou QT [11]
  • Vogt PK [10]
  • Yang DH [10]
  • Yang S [10]
  • Cong ZT [8]
  • Feng W [8]
  • Feng WB [8]
  • Li H [8]
  • Li J [8]
  • Lin S [8]
  • Mai Y [8]
  • Xu YN [8]
  • Ye CY [8]
  • Hart JR [7]
  • Cai X [6]
  • Cai XQ [6]
  • Zhao F [6]
  • Han W [5]
  • Li C [5]
  • Xu HE [5]
  • Zheng C [5]
  • Hassanzadeh-ghassabeh G [4]
  • Liang A [4]
  • Pan C [4]
  • Quezada A [4]
  • Schoonooghe S [4]
  • Shui W [4]
  • Ueno L [4]
  • Xia T [4]
  • Zou X [4]
  • Bassi G [3]
  • Bathgate RAD [3]
  • Chen CW [3]
  • Chen X [3]
  • Chen XY [3]
  • Cong Z [3]
  • Dai A [3]
  • Dai AT [3]
  • Eric Xu H [3]
  • Favalli N [3]
  • Li CH [3]
  • Li W [3]
  • Liu H [3]
  • Neri D [3]
  • Shen C [3]
  • Wang J [3]
  • Wang Y [3]
  • Wang YB [3]
  • Xu YW [3]
  • Yan J [3]
  • Yan JH [3]
  • Ye C [3]
  • Zhu Q [3]
  • Cui J [2]
  • Fang M [2]
  • Li G [2]
  • Wang M [2]
  • Xu H [2]
  • Yin W [2]
  • Zhang Y [2]
  • Fan S [1]
  • Lin B [1]
  • Wu C [1]
  • Zhuang J [1]

Author by ORCID

  • Wang MW [27]
  • Yang D [23]
  • Zhou Q [16]
  • Vogt PK [10]
  • Hart JR [7]
  • Ueno L [4]
  • Zou X [4]
  • Bathgate RAD [3]
  • Xu Y [3]
  • Eric Xu H [3]
  • Liu H [3]
  • Cui J [2]
  • Wu C [1]

Journal

  • PNAS [10]
  • CELL DISCOV [6]
  • STRUCTURE [5]
  • ACTA PHARM SIN B [4]
  • NAT COMMUN [3]
  • J AM CHEM SOC [1]

Software

  • CRYOSPARC [3]
  • COOT [1]
  • PHENIX [1]

Microscope

  • FEI TITAN KRIOS [17]
  • TFS KRIOS [11]
  • FEI TECNAI 10 [1]

Electron Source

  • OTHER [25]
  • FIELD EMISSION GUN [4]

Film or detector model

  • GATAN K3 6K X 4K [29]

External links

  • AlphaFold DB [29]
  • Gene Ontology [29]
  • PDB [29]
  • PDBe-Kb [29]
  • Pfam [29]
  • UniProt [29]
  • InterPro [19]
  • Complex Portal [14]
  • ChEBI [12]
  • DrugBank [12]
  • ChEMBL [10]
Sort by: Download
Showing 1 - 10 of 29. Page 1 of 3
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EMD-63458
Download Map
3D View
Cryo-EM structure of PI3Kalpha H1047R in complex with compound UCL-TRO-1938
Release date: Oct. 15, 2025
Resolution: 2.94 Å
EM Method: Single-particle
Fitted PDBs: 9lws
Q-score: 0.431

Liu X, Zhou Q, Chen Y, Han W, Li J, Mai Y, Wang MW

Cell Discov (2025) 11 pp. 77-77 [ DOI: doi:10.1038/s41421-025-00833-w Pubmed: 40968123 ]

EMD-63456
Download Map
3D View
Cryo-EM structure of PI3Kalpha in complex with compound UCL-TRO-1938
Release date: Oct. 1, 2025
Resolution: 3.17 Å
EM Method: Single-particle
Fitted PDBs: 9lwq
Q-score: 0.497

Liu X, Zhou Q, Chen Y, Han W, Li J, Mai Y, Wang MW

Cell Discov (2025) 11 pp. 77-77 [ DOI: doi:10.1038/s41421-025-00833-w Pubmed: 40968123 ]

EMD-63457
Download Map
3D View
Cryo-EM structure of PI3Kalpha H1047R in complex with compound UCL-TRO-1938
Release date: Oct. 1, 2025
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 9lwr
Q-score: 0.437

Liu X, Zhou Q, Chen Y, Han W, Li J, Mai Y, Wang MW

Cell Discov (2025) 11 pp. 77-77 [ DOI: doi:10.1038/s41421-025-00833-w Pubmed: 40968123 ]

EMD-61941
Download Map
3D View
Cryo-EM structure of the DSO-5a-bound human BRS3-Gq complex
Release date: Aug. 27, 2025
Resolution: 2.83 Å
EM Method: Single-particle
Fitted PDBs: 9k07
Q-score: 0.547

Li J, Li C, Zhou Q, Han W, Fang M, Xu Y, Mai Y, Zhang Y, Cui J, Xu HE, Zhang Y, Yin W, Wang MW

Acta Pharm Sin B (2025) 15 pp. 5231-5243 [ DOI: doi:10.1016/j.apsb.2025.06.025 Pubmed: 41132856 ]

EMD-62014
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3D View
Cryo-EM structure of the unliganded human melanocortin receptor 3 MC3R -Gs complex
Release date: Aug. 6, 2025
Resolution: 2.75 Å
EM Method: Single-particle
Fitted PDBs: 9k3f

Feng W, Zhou Q, Zheng C, Yang D, Wang MW

Structure (2025) 33 pp. 1074-1087.e5 [ Pubmed: 40157361 DOI: doi:10.1016/j.str.2025.03.004 ]

EMD-62015
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3D View
Cryo-EM structure of the unliganded human melanocortin receptor 5 MC5R -Gs complex
Release date: Aug. 6, 2025
Resolution: 2.86 Å
EM Method: Single-particle
Fitted PDBs: 9k3h
Q-score: 0.472

Feng W, Zhou Q, Zheng C, Yang D, Wang MW

Structure (2025) 33 pp. 1074-1087.e5 [ Pubmed: 40157361 DOI: doi:10.1016/j.str.2025.03.004 ]

EMD-62017
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3D View
Cryo-EM structure of the unliganded human melanocortin receptor 4 MC4R -Gs complex
Release date: Aug. 6, 2025
Resolution: 3.12 Å
EM Method: Single-particle
Fitted PDBs: 9k3k

Feng W, Zhou Q, Zheng C, Yang D, Wang MW

Structure (2025) 33 pp. 1074-1087.e5 [ Pubmed: 40157361 DOI: doi:10.1016/j.str.2025.03.004 ]

EMD-62018
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3D View
Cryo-EM structure of the unliganded human melanocortin receptor 2 MC2R -Gs complex
Release date: Aug. 6, 2025
Resolution: 3.01 Å
EM Method: Single-particle
Fitted PDBs: 9k3l

Feng W, Zhou Q, Zheng C, Yang D, Wang MW

Structure (2025) 33 pp. 1074-1087.e5 [ Pubmed: 40157361 DOI: doi:10.1016/j.str.2025.03.004 ]

EMD-62024
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3D View
Cryo-EM structure of the unliganded human melanocortin receptor 1 MC1R -Gs complex
Release date: Aug. 6, 2025
Resolution: 2.98 Å
EM Method: Single-particle
Fitted PDBs: 9k3p

Feng W, Zhou Q, Zheng C, Yang D, Wang MW

Structure (2025) 33 pp. 1074-1087.e5 [ Pubmed: 40157361 DOI: doi:10.1016/j.str.2025.03.004 ]

EMD-63455
Download Map
3D View
Cryo-EM structure of the unliganded human BRS3-Gq complex
Release date: July 16, 2025
Resolution: 2.93 Å
EM Method: Single-particle
Fitted PDBs: 9lwp
Q-score: 0.485

Li J, Li C, Zhou Q, Han W, Fang M, Xu Y, Mai Y, Zhang Y, Cui J, Xu HE, Zhang Y, Yin W, Wang MW

Acta Pharm Sin B (2025) 15 pp. 5231-5243 [ DOI: doi:10.1016/j.apsb.2025.06.025 Pubmed: 41132856 ]

Sort by: Download
Showing 1 - 10 of 29. Page 1 of 3
Display:
Statistics
×

Download











































Preview first 10
Download

Filter By

Current Database

  • EMDB [29]

Current status

  • REL [29]

Sample type

  • Complex [29]
  • Protein [29]
  • Ligand [17]

Organism

  • Homo sapiens [29]
  • Bos taurus [14]
  • Synthetic construct [12]
  • Rattus norvegicus [3]
  • Oplophorus gracilirostris [2]
  • Lama glama [2]
  • Mus musculus [1]

EM Method

  • Single-particle [29]

Resolution

  • ≥ 2Å and < 3Å [16]
  • ≥ 3Å and < 4Å [13]

Model molecular weight

  • 100-250 kDa [29]

Release Date

  • 2025 [11]
  • 2024 [2]
  • 2023 [9]
  • 2022 [7]

Author by name

  • Wang MW [29]
  • Zhou Q [29]
  • Liu X [23]
  • Yang D [23]
  • Xu Y [15]
  • Chen Y [14]
  • Wang M-W [13]
  • Zhao FH [11]
  • Zhou QT [11]
  • Vogt PK [10]
  • Yang DH [10]
  • Yang S [10]
  • Cong ZT [8]
  • Feng W [8]
  • Feng WB [8]
  • Li H [8]
  • Li J [8]
  • Lin S [8]
  • Mai Y [8]
  • Xu YN [8]
  • Ye CY [8]
  • Hart JR [7]
  • Cai X [6]
  • Cai XQ [6]
  • Zhao F [6]
  • Han W [5]
  • Li C [5]
  • Xu HE [5]
  • Zheng C [5]
  • Hassanzadeh-ghassabeh G [4]
  • Liang A [4]
  • Pan C [4]
  • Quezada A [4]
  • Schoonooghe S [4]
  • Shui W [4]
  • Ueno L [4]
  • Xia T [4]
  • Zou X [4]
  • Bassi G [3]
  • Bathgate RAD [3]
  • Chen CW [3]
  • Chen X [3]
  • Chen XY [3]
  • Cong Z [3]
  • Dai A [3]
  • Dai AT [3]
  • Eric Xu H [3]
  • Favalli N [3]
  • Li CH [3]
  • Li W [3]
  • Liu H [3]
  • Neri D [3]
  • Shen C [3]
  • Wang J [3]
  • Wang Y [3]
  • Wang YB [3]
  • Xu YW [3]
  • Yan J [3]
  • Yan JH [3]
  • Ye C [3]
  • Zhu Q [3]
  • Cui J [2]
  • Fang M [2]
  • Li G [2]
  • Wang M [2]
  • Xu H [2]
  • Yin W [2]
  • Zhang Y [2]
  • Fan S [1]
  • Lin B [1]
  • Wu C [1]
  • Zhuang J [1]

Author by ORCID

  • Wang MW [27]
  • Yang D [23]
  • Zhou Q [16]
  • Vogt PK [10]
  • Hart JR [7]
  • Ueno L [4]
  • Zou X [4]
  • Bathgate RAD [3]
  • Xu Y [3]
  • Eric Xu H [3]
  • Liu H [3]
  • Cui J [2]
  • Wu C [1]

Journal

  • PNAS [10]
  • CELL DISCOV [6]
  • STRUCTURE [5]
  • ACTA PHARM SIN B [4]
  • NAT COMMUN [3]
  • J AM CHEM SOC [1]

Software

  • CRYOSPARC [3]
  • COOT [1]
  • PHENIX [1]

Microscope

  • FEI TITAN KRIOS [17]
  • TFS KRIOS [11]
  • FEI TECNAI 10 [1]

Electron Source

  • OTHER [25]
  • FIELD EMISSION GUN [4]

Film or detector model

  • GATAN K3 6K X 4K [29]

External links

  • AlphaFold DB [29]
  • Gene Ontology [29]
  • PDB [29]
  • PDBe-Kb [29]
  • Pfam [29]
  • UniProt [29]
  • InterPro [19]
  • Complex Portal [14]
  • ChEBI [12]
  • DrugBank [12]
  • ChEMBL [10]