Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!
EMD-61941
Cryo-EM structure of the DSO-5a-bound human BRS3-Gq complex
EMD-61941
Single-particle2.83 Å
Deposition: 15/10/2024Map released: 27/08/2025
Last modified: 05/11/2025
Sample Organism:
Homo sapiens,
Oplophorus gracilirostris,
Mus musculus,
Rattus norvegicus,
Bos taurus,
Lama glama
Sample: Cryo-EM structure of the DSO-5a-bound human BRS3-miniGq complex
Fitted models: 9k07
Deposition Authors: Li J, Li C, Zhou Q, Han W, Fang M, Xu Y, Mai Y, Cui J
,
Xu H,
Zhang Y,
Yin W,
Wang M
Sample: Cryo-EM structure of the DSO-5a-bound human BRS3-miniGq complex
Fitted models: 9k07
Deposition Authors: Li J, Li C, Zhou Q, Han W, Fang M, Xu Y, Mai Y, Cui J
,
Xu H,
Zhang Y,
Yin W,
Wang M
Divergent activation patterns of BRS3 revealed by two Chinese herb-derived agonists.
Li J,
Li C,
Zhou Q,
Han W,
Fang M,
Xu Y,
Mai Y,
Zhang Y,
Cui J
,
Xu HE,
Zhang Y,
Yin W,
Wang MW
(2025) Acta Pharm Sin B , 15 , 5231 - 5243
,
Xu HE,
Zhang Y,
Yin W,
Wang MW
(2025) Acta Pharm Sin B , 15 , 5231 - 5243
Grant Support:
- National Natural Science Foundation of China (NSFC): 82273961 (China)
- National Natural Science Foundation of China (NSFC): 82073904 (China)
- National Natural Science Foundation of China (NSFC): 81872915 (China)
- National Natural Science Foundation of China (NSFC): 32171189 (China)
- National Natural Science Foundation of China (NSFC): 32130022 (China)
- National Natural Science Foundation of China (NSFC): 82121005 (China)
- Other government: 2022YFA1302900 (China)
- Other government: 2022YFC2703105 (China)
- Other government: 2021278 (China)
- Other government: CXTD2023010 (China)
- Other government: 2019B090904008 (China)
- Other government: 2021B0909050003 (China)
- Other government: XDB37030103 (China)
- Other government: 2019SHZDZX02 (China)
- Other government: LG-GG-202204-01 (China)
- Other government: 2021ZD0203400 (China)
- Other government: ZDKJ2021028 (China)
